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Experimental Biology and Medicine | 1942

Yeast-Growth-Promoting Effect of Diaminocarboxylic Acid Derived from Biotin.

Vincent du Vigneaud; Karl Dittmer; Klaus Hofmann; Donald B. Melville

Summary The diaminocarboxylie acid resulting from the hydrolysis of the urea ring of biotin is capable of stimulating the growth of yeast in a biotin-free medium. The compound possesses about 10% of the activity of biotin. The yeast-growth-promoting activity of the diaminocarboxylic acid is not inhibited by avidin.


Journal of Biological Chemistry | 1941

Characterization of the functional groups of biotin.

Klaus Hofmann; Donald B. Melville; V. Du Vigneaud


Journal of Biological Chemistry | 1947

A synthesis of methionine containing radiocarbon in the methyl group.

Donald B. Melville; Julian R. Rachele; Elizabeth B. Keller


Journal of Biological Chemistry | 1942

The structure of biotin: a study of desthiobiotin.

V. Du Vigneaud; Donald B. Melville; Karl Folkers; Donald E. Wolf; Ralph Mozingo; John C. Keresztesy; Stanton A. Harris


Journal of Biological Chemistry | 1956

Ergothioneine in microorganisms.

Donald B. Melville; Dorothy S. Genghof; Edward Inamine; Vladimir Kovalenko


Science | 1940

On the identity of vitamin H with biotin.

V. Du Vigneaud; Donald B. Melville; Paul György; Catharine S. Rose


Science | 1940

A Further Note on the Identity of Vitamin H with Biotin.

Paul György; Catharine S. Rose; Klaus Hofmann; Donald B. Melville; V. Du Vigneaud


Science | 1940

THE POSSIBLE IDENTITY OF VITAMIN H WITH BIOTIN AND COENZYME R

Paul György; Donald B. Melville; Dean Burk; Vincent du Vigneaud


Science | 1944

THE POSSIBLE SYNTHESIS OF BIOTIN FROM DESTHIOBIOTIN BY YEAST AND THE ANTI-BIOTIN EFFECT OF DESTHIOBIOTIN FOR L. CASEI

Karl Dittmer; Donald B. Melville; V. Du Vigneaud


Journal of Biological Chemistry | 1974

Participation of an Intermediate Sulfoxide in the Enzymatic Thiolation of the Imidazole Ring of Hercynine to Form Ergothioneine

Yoshinori Ishikawa; Sheila E. Israel; Donald B. Melville

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