Donald C. Brodie

Effect of Electrolytes on Arterial Muscle Contraction

The effect of specific electrolyte changes and of desoxycorticosterone on the responsiveness of vascular smooth muscle to epinephrine was studied using rabbit aortic strips. Low sodium increases, while high sodium decreases the epinephrine response. Conversely, low potassium decreases, while high potassium increases the epinephrine response. Desoxycorticosterone potentiates the epinephrine response in a manner qualitatively similar to that of high potassium, but different from that of low sodium potentiation.

The Evolution of the Clinical Pharmacy Concept

SOCIAL CHANGE TAKES PLACE in a variety of ways. It may come about as a result of long-identified needs which require a mandated social action at the highest level of authority. This type of change came about in the United States with the passage of the Social Security Act in 1933 and such amendments that have taken place subsequently, such as Titles 18 and 1Θ (Medicare and Medicaid, respectively). Another example of change of

The Pharmacy Service of Memorial Hospital Medical Center

This article identifies the scope of activities, needs and subjects of a clinical pharmacy service program in a progressive community hospital. Even after ten years of constant effort, a comprehensive hospital clinical pharmacy program still rquires continual review, changes, and improvements.