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Dive into the research topics where Donald Leake is active.

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Featured researches published by Donald Leake.


Journal of Oral and Maxillofacial Surgery | 1987

Evaluation of autologous cancellous bone grafting of mandibular discontinuity defects in dogs using a Dacron-urethane prosthesis.

Harry C. Schwartz; Donald Leake; A. Pizzoferrato

Reconstruction of 2 cm discontinuity defects using autologous cancellous bone chips and a Dacron-urethane prosthesis was evaluated in four canine mandibles. Histologic studies were performed on specimens taken six and 12 months after bone grafting. All four grafts were completely incorporated, producing a reconstruction that conformed precisely to the desired shape. Remodeling resulted in a trabecular pattern similar to that of the normal mandible. The prosthesis was well tolerated and did not elicit an inflammatory response.


Journal of Prosthetic Dentistry | 1979

Carbon-coated subperiosteal dental implants for fixed and movable prostheses

Donald Leake; Omer K. Reed; Jack Armitage; Jack C. Bokros; Axel D. Haubold

Subperiosteal dental implants are not intended to replace conventional dentistry but provide an alternative method of treatment for the patient who cannot otherwise tolerate a dental prosthesis. Success can be achieved in the maxillae and in the mandible without the risk of serious complications. There are good prospects for a long-term favorable prognosis when appropriate surgical and prosthodontic criteria are observed.


Annals of Plastic Surgery | 1979

Use of a craniotome for obtaining cancellous bone and marrow from the ilium.

Harry C. Schwartz; Donald Leake

The ilium is a rich source of cancellous bone and marrow for grafting. Grafts can be harvested very rapidly with a standard craniotome. The clutch mechanism prevents inadvertent soft tissue injury if both cortical plates are perforated. The surgical approach is similar to that used in other techniques. No complications have been encountered.


Journal of Prosthetic Dentistry | 1979

Vapor-deposited carbon-coated tooth root implants: preliminary evaluation of a stylized tooth implant system in dogs.

Silvano Michieli; Donald Leake; Scott Freeman; Jack C. Bokros; Axel D. Haubold; A. Pizzoferrato

The results of this preliminary evaluation of a tooth implant model combining a stylized tooth root design and a thin, highly biocompatible microporous carbon coating, although tentative, add support to the feasibility of developing a statisfactory system for the immediate replacement of selected teeth in healthy bone.


Artificial Cells, Blood Substitutes, and Biotechnology | 1979

Preliminary Histologic Evaluation of A Biocompatible Mesh for Tracheal Reconstruction

Arturo Pizzoferrato; Donald Leake; Silvano Michieli; Axel D. Haubold; Scott Freeman

The purpose of this study was to evaluate a porous Dacron - urethane mesh tracheal prosthesis in large dogs with surgically created discontinuous defects of the cervical trachea. Some protheses were carbon coated in an attempt to improve biocompatibility. Histology was performed on 2 dogs. The mucosa regenerated entirely covering the prosthesis. Respiratory epithelium was formed over a large central portion of the tracheas.


International Journal of Oral Surgery | 1981

A new arch bar for oral surgery

Akira Hasegawa; Donald Leake

A new universal arch bar for intermaxillary fixation has been developed. This arch bar was fabricated as a wave-shaped, thin metal plate with soldered buttons on the bucco-labial aspect. It is light and flexible, yet strong enough to provide excellent fixation in the treatment of fractures of the maxilla and/or mandible. It is a universal bar: the superior and inferior borders are identical. Clinical application has been broad including trauma and cases of orthognathic surgery.


Oral Surgery, Oral Medicine, Oral Pathology | 1980

Surgical lengthening of the mandible: A laboratory model

Silvano Michieli; Arturo Pizzoferrato; Scott Freeman; Donald Leake

Mandibular lengthening in mongrel dogs was evaluated in four animals. Extraoral approaches were used for mandibular exposure. Step osteotomies were performed on the buccal aspect and oblique osteotomies were performed on the lingual aspect of the mandible. The anterior fragment of the mandible was advanced 10 mm. A Dacron-urethane mesh tray, in the form of the mandible, was placed across the defect as a container of bone graft material and to help stabilize the segments. The bone graft material was harvested by aspirating the bone particles formed when the osteotomy cuts were made, thus creating a bone slurry which was placed within the implant. The results suggest that the use of the implant tray in conjunction with the bony slurry provided an appropriate physiologic setting for rapid new bone formation, restoring continuity to the defect.


Artificial Cells, Blood Substitutes, and Biotechnology | 1979

Design and Materials Evaluation for A Dental Implant System: Carbon Coated Tooth Replicas

Silvano Michieli; Donald Leake; A. Pizzoferrato; Axel D. Haubold; J. Bokros

32 carbon coated tooth replicas were implanted in the jaws of 8 mongrel dogs for periods ranging from 3 months to 2 years. Fourteen of 16 molor implants and 10 of 16 premolar implants had 0.5 min. of mobility or less. Histology of specimens from 4 dogs sacrificed at 3 months showed new bone directly in contact with the implant surface.


Archives of Otolaryngology-head & Neck Surgery | 1979

Interface Radiation Dosimetry in Mandibular Reconstruction

Harry C. Schwartz; Myron Wollin; Donald Leake; A. Robert Kagan


Oral Surgery, Oral Medicine, Oral Pathology | 1984

Histologic evaluation of carbon-coated subperiosteal dental implants in dogs

Silvano Michieli; Arturo Pizzoferrato; Donald Leake

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A. Robert Kagan

Cedars-Sinai Medical Center

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