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Dive into the research topics where Dorothy S. Slusarchyk is active.

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Featured researches published by Dorothy S. Slusarchyk.


Cellular and Molecular Life Sciences | 1982

Activity of sulfa drugs and dihydrofolate reductase inhibitors againstCandida albicans

Karen Bush; Joan S. Freudenberger; Dorothy S. Slusarchyk; Richard B. Sykes; Edward Meyers

Growth ofCandida albicans can be inhibited by sulfa drugs which prevent biosynthesis of folic acid. The dihydrofolate reductase (E.C. 1.5.1.3) inhibitors aminopterin and methotrexate also exhibit anticandidal activity, but trimethoprim does not. Kinetic evaluations withC. albicans dihydrofolate reductase indicate that methotrexate and aminopterin are tight-binding inhibitors whereas trimethoprim binds poorly.


The Journal of Antibiotics | 1984

Muraceins - Muramyl peptides produced by Nocardia orientalis as angiotensin-converting enzyme inhibitors I. Taxonomy, fermentation and biological properties.

Karen Bush; Paul R. Henry; Dorothy S. Slusarchyk


The Journal of Antibiotics | 1970

Isolation,characterization,and structure of rabelomycin,a new antibiotic

Wen-Chih Liu; William L. Parker; Dorothy S. Slusarchyk; Gail L. Greenwood; Susan F. Graham; Edward Meyers


The Journal of Antibiotics | 1978

IONOMYCIN, A NEW POLYETHER ANTIBIOTIC

Wen-Chin Liu; Dorothy S. Slusarchyk; Gail L. Astle; William H. Trejo; William E. Brown; Edward Meyers


The Journal of Antibiotics | 1987

XYLOCANDIN: A NEW COMPLEX OF ANTIFUNGAL PEPTIDES

Edward Meyers; G. S. Bisacchi; Loretta Dean; Wen-Chin Liu; B. Minassian; Dorothy S. Slusarchyk; Richard B. Sykes; S. K. Tanaka; William H. Trejo


The Journal of Antibiotics | 1984

Phenacein--an angiotensin-converting enzyme inhibitor produced by a streptomycete. I. Taxonomy, fermentation and biological properties.

Karen Bush; Paul R. Henry; Margaret Souser-Woehleke; William H. Trejo; Dorothy S. Slusarchyk


The Journal of Antibiotics | 1985

Catacandins, novel anticandidal antibiotics of bacterial origin

Dward Meyers; Raymond Cooper; Loretta Dean; Janice H. Johnson; Dorothy S. Slusarchyk; William H. Trejo; Pushpa D. Singh


The Journal of Antibiotics | 1970

Janiemycin,a new peptide antibiotic

Edward Meyers; Frank Lee Weisenborn; Felix Pansy; Dorothy S. Slusarchyk; Malcolm H. Von Saltza; Marlene L. Rathnum; William L. Parker


The Journal of Antibiotics | 1973

EM49, a new peptide antibiotic. 3. biological characterization in vitro and in vivo.

Edward Meyers; Felix Edward Pansy; Harold I. Basch; Ronald J. Mcripley; Dorothy S. Slusarchyk; Susan F. Graham; William H. Trejo


Archive | 1983

Phenazine ACE inhibitor produced from streptomyces species

Karen Bush; Dorothy S. Slusarchyk; Wen-Chih Liu

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