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Dive into the research topics where Douglas Crawford-Brown is active.

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Featured researches published by Douglas Crawford-Brown.


Nature | 2015

Reduced carbon emission estimates from fossil fuel combustion and cement production in China

Zhu Liu; Dabo Guan; Wei Wei; Steven J. Davis; Philippe Ciais; Jin Bai; Shushi Peng; Qiang Zhang; Klaus Hubacek; Gregg Marland; Robert Joseph Andres; Douglas Crawford-Brown; Jintai Lin; Hongyan Zhao; Chaopeng Hong; Thomas A Boden; Kuishuang Feng; Glen P. Peters; Fengming Xi; Junguo Liu; Yuan Li; Yu Zhao; Ning Zeng; Kebin He

Nearly three-quarters of the growth in global carbon emissions from the burning of fossil fuels and cement production between 2010 and 2012 occurred in China. Yet estimates of Chinese emissions remain subject to large uncertainty; inventories of China’s total fossil fuel carbon emissions in 2008 differ by 0.3 gigatonnes of carbon, or 15 per cent. The primary sources of this uncertainty are conflicting estimates of energy consumption and emission factors, the latter being uncertain because of very few actual measurements representative of the mix of Chinese fuels. Here we re-evaluate China’s carbon emissions using updated and harmonized energy consumption and clinker production data and two new and comprehensive sets of measured emission factors for Chinese coal. We find that total energy consumption in China was 10 per cent higher in 2000–2012 than the value reported by China’s national statistics, that emission factors for Chinese coal are on average 40 per cent lower than the default values recommended by the Intergovernmental Panel on Climate Change, and that emissions from China’s cement production are 45 per cent less than recent estimates. Altogether, our revised estimate of China’s CO2 emissions from fossil fuel combustion and cement production is 2.49 gigatonnes of carbon (2 standard deviations = ±7.3 per cent) in 2013, which is 14 per cent lower than the emissions reported by other prominent inventories. Over the full period 2000 to 2013, our revised estimates are 2.9 gigatonnes of carbon less than previous estimates of China’s cumulative carbon emissions. Our findings suggest that overestimation of China’s emissions in 2000–2013 may be larger than China’s estimated total forest sink in 1990–2007 (2.66 gigatonnes of carbon) or China’s land carbon sink in 2000–2009 (2.6 gigatonnes of carbon).


Nature | 2013

Energy policy: A low-carbon road map for China

Zhu Liu; Dabo Guan; Douglas Crawford-Brown; Qiang Zhang; Kebin He; Jianguo Liu

Recycling, renewables and a reinvigorated domestic energy market will allow China to lead the world in low-carbon development, say Zhu Liu and colleagues.


Environmental Science & Technology | 2011

Mapping flows of embodied emissions in the global production system.

Andrew Skelton; Dabo Guan; Glen P. Peters; Douglas Crawford-Brown

Environmentally extended multiregional input-output (MRIO) analysis can be used to investigate final production and consumption attributions of emissions. As the distinction between the two attributions has been brought to the attention of policy-makers, there is an ever greater need to understand how and why they differ, by analyzing the connections between production and consumption activities. Seeking to meet this need, we present an approach for mapping flows of embodied emissions through a Leontief production system. The approach, seen as an extension of Structural Path Analysis (SPA), provides an exhaustive map of supply chain linkages between final production and consumption attributions of emissions. Whereas SPA is traditionally used to extract and rank individual supply chains according to the emissions occurring at the end of each chain, the mapping approach considers emissions embodied in the flows of intermediate products linking different economic sectors along supply chains. Illustrative results are presented from a global MRIO model and CO(2) emissions for 2004. The emissions embodied in a sectors total output of products is also of interest: a method for calculating this is presented and shown to provide further insight into where in the production system a sectors overall emissions impact is concentrated.


Science of The Total Environment | 2009

The built environment and health: impacts of pedestrian-friendly designs on air pollution exposure.

Audrey de Nazelle; Daniel A. Rodriguez; Douglas Crawford-Brown

In the wake of the growing popularity of pedestrian-oriented community designs, it is timely to assess potential risk trade-offs of such urban planning strategies. Pedestrian-friendly designs are currently being called for and implemented in the US to tackle in particular problems associated with insufficient physical activity in the population. Unintended consequences may emerge, however, especially due to potential increases in the inhalation of pollutants as the population walking or cycling in polluted environments increases. A risk assessment of such built environment transformations was undertaken to evaluate quantitatively the competing risks and benefits of community design changes in active travel. A simulation model, built incorporating research from the fields of transportation, environmental sciences and exposure analysis, is applied to a case study area that undergoes hypothetical urban transformations. We find that the simulated population experiences roughly the same number of days in a year with decreases as number of days with increases in energy expenditure or inhalation of pollutants. In the 5% of days with greatest shifts, PM(10) inhalation was shown to increase by 175% or more, while the 5% of days of greatest decreases exhibited reductions of 45% or more (with similar results for ozone). Of particular concern, some individuals are shown to double their intake of the pollutants on high pollution days. However, uncertainty in the estimates is high. In particular, interpretations are very different according to the approach used to characterize year-long activity patterns. This innovative risk assessment uncovers critical gaps in the literature that must be further researched to allow essential comprehensive analyses of planning decisions.


Environmental Science & Technology | 2014

Decoupling analysis and socioeconomic drivers of environmental pressure in China.

Sai Liang; Zhu Liu; Douglas Crawford-Brown; Yafei Wang; Ming Xu

Chinas unprecedented change offers a unique opportunity for uncovering relationships between economic growth and environmental pressure. Here we show the trajectories of Chinas environmental pressure and reveal underlying socioeconomic drivers during 1992-2010. Mining and manufacturing industries are the main contributors to increasing environmental pressure from the producer perspective. Changes in urban household consumption, fixed capital formation, and exports are the main drivers from the consumer perspective. While absolute decoupling is not realized, China has in general achieved relative decoupling between economic growth and environmental pressure. Chinas decoupling performance has four distinguishable periods, closely aligning with nation-wide major policy adjustments, which indicates significant impact of Chinas national socioeconomic policies on its environmental pressure. Material intensity change is the main contributor to the mitigation of environmental pressure, except for ammonia nitrogen, solid wastes, aquatic Cu, and aquatic Zn. Production structure change is the largest contributor to mitigate ammonia nitrogen emissions, and final demand structure change is the largest contributor to mitigate emissions of solid wastes, aquatic Cu, and aquatic Zn. We observe materialization trends for Chinas production structure and final demand structure during 2002-2007. Environmental sustainability can only be achieved by timely technology innovation and changes of production structure and consumption pattern.


International Journal of Radiation Biology | 2002

Explanation of protective effects of low doses of γ -radiation with a mechanistic radiobiological model

H. Schöllnberger; R. E. J. Mitchel; Edouard I. Azzam; Douglas Crawford-Brown; Werner Hofmann

Purpose : To test whether data that show protective effects of low doses against spontaneous neoplastic transformation of C3H 10T1/2 cells can be explained with a biomathematical model that includes radioprotective mechanisms. To link important features of the model to known biological processes. Materials and methods : The model simulates double-strand break formation in transcriptionally active and in bulk DNA, translocation of DNA segments, and the fixation of damage at mitosis; promotion is also included. The model equations were solved numerically using a stiff solver. Results : The data were successfully simulated by the model: cell transformation-reducing effects of low doses of γ-radiation delivered at low dose-rates are explained by radiation-inducible DNA repair and enzymatic scavenging. Conclusions : The model successfully simulates experimental data. The highly nonlinear features of the data point to a nonlinear dose-effect relationship at low doses and indicate that linear extrapolation from moderate (or high) to low doses and dose-rates may not be justified for in vitro studies of the cell line under consideration.


Radiation Research | 2007

Detrimental and Protective Bystander Effects: A Model Approach

H. Schöllnberger; R. E J. Mitchel; J. L. Redpath; Douglas Crawford-Brown; Werner Hofmann

Abstract Schöllnberger, H., Mitchel, R. E. J., Redpath, J. L., Crawford-Brown, D. J. and Hofmann, W. Detrimental and Protective Bystander Effects: A Model Approach. Radiat. Res. 168, 614–626 (2007). This work integrates two important cellular responses to low doses, detrimental bystander effects and apoptosis-mediated protective bystander effects, into a multistage model for chromosome aberrations and in vitro neoplastic transformation: the State-Vector Model. The new models were tested on representative data sets that show supralinear or U-shaped dose responses. The original model without the new low-dose features was also tested for consistency with LNT-shaped dose responses. Reductions of in vitro neoplastic transformation frequencies below the spontaneous level have been reported after exposure of cells to low doses of low-LET radiation. In the current study, this protective effect is explained with bystander-induced apoptosis. An important data set that shows a low-dose detrimental bystander effect for chromosome aberrations was successfully fitted by additional terms within the cell initiation stage. It was found that this approach is equivalent to bystander-induced clonal expansion of initiated cells. This study is an important step toward a comprehensive model that contains all essential biological mechanisms that can influence dose–response curves at low doses.


International Journal of Food Microbiology | 2002

Sensitivity analysis of Salmonella enteritidis levels in contaminated shell eggs using a biphasic growth model.

Heejeong K. Latimer; Lee-Ann Jaykus; Roberta A. Morales; Peter Cowen; Douglas Crawford-Brown

Salmonella enteritidis (SE) is a common foodbome pathogen, the transmission of which is primarily associated with the consumption of contaminated Grade A shell eggs. In order to estimate the level of SE present in raw shell eggs, it is necessary to consider the protective effects of the egg albumin, which effectively inhibits SE growth in a time- and temperature-dependent manner. In this study, a SE growth model was produced by combining two mathematical equations that described both the extended lag phase of SE growth (food component) and a SE growth model (pathogen component). This biphasic growth model was then applied to various egg handling scenarios based on the farm-to-table continuum, including in-line and off-line processing facilities with consideration of key events in production, processing, transportation, and storage. Seasonal effects were also studied. Monte Carlo simulation was used to characterize variability in temperature and time parameter values influencing the level of SE to which individuals are exposed. The total level of SE consumed was estimated under best, most likely, and time-temperature abusive handling scenarios. The model estimated that, in most cases, there was no SE growth in contaminated eggs handled under most likely practices, because 10-70% of the yolk membrane remained intact. Under abusive handling scenarios, complete loss of yolk membrane integrity frequently occurred by the time eggs reach the distribution phase, followed by subsequent SE growth, which was often quite rapid. In general, the effect of season and processing method (in-line vs. off-line) was minimal. Further sensitivity analysis demonstrated that the initial SE contamination level significantly influenced the final exposure levels only under no-abuse or mildly abusive conditions. The results of our study suggest that, for maximum reduction of SE exposure level, cooling strategies should not only focus on the on-farm or processing phases, but should emphasize the importance of cooling strategies at the distribution and consumer phases of the farm-to-fork continuum.


Health Physics | 2000

Modeling energy deposition and cellular radiation effects in human bronchial epithelium by radon progeny alpha particles.

Werner Hofmann; Margaret G. Ménache; Douglas Crawford-Brown; Randall S. Caswell; Lisa R. Karam

Energy deposition and cellular radiation effects arising from the interaction of single 218Po and 214Po alpha particles with basal and secretory cell nuclei were simulated for different target cell depths in the bronchial epithelium of human airway generations 2, 4, 6, and 10. To relate the random chord lengths of alpha particle tracks through spherical cell nuclei to the resulting biological endpoints, probabilities per unit track length for different cellular radiation effects as functions of LET were derived from in vitro experiments. The radiobiological data employed in the present study were inactivation and mutation (mutant frequency at the HPRT gene) in V79 Chinese hamster cells and inactivation and transformation in C3H 10T1/2 cells. Based on computed LET spectra and relative frequencies of target cells, probabilities for transformation, mutation, and cell killing in basal and secretory cells were computed for a lifetime exposure of 20 WLM. While predicted transformation probabilities were about two orders of magnitude higher than mutation probabilities, they were still about two orders of magnitude lower than inactivation probabilities. Furthermore transformation probabilities for basal cells are generally higher than those for secretory cells, and 214Po alpha particles are primarily responsible for transformations in bronchial target cells.


Risk Analysis | 2013

Modeling imbalanced economic recovery following a natural disaster using input-output analysis

Jun Li; Douglas Crawford-Brown; Mark Syddall; Dabo Guan

Input-output analysis is frequently used in studies of large-scale weather-related (e.g., Hurricanes and flooding) disruption of a regional economy. The economy after a sudden catastrophe shows a multitude of imbalances with respect to demand and production and may take months or years to recover. However, there is no consensus about how the economy recovers. This article presents a theoretical route map for imbalanced economic recovery called dynamic inequalities. Subsequently, it is applied to a hypothetical postdisaster economic scenario of flooding in London around the year 2020 to assess the influence of future shocks to a regional economy and suggest adaptation measures. Economic projections are produced by a macro econometric model and used as baseline conditions. The results suggest that Londons economy would recover over approximately 70 months by applying a proportional rationing scheme under the assumption of initial 50% labor loss (with full recovery in six months), 40% initial loss to service sectors, and 10-30% initial loss to other sectors. The results also suggest that imbalance will be the norm during the postdisaster period of economic recovery even though balance may occur temporarily. Model sensitivity analysis suggests that a proportional rationing scheme may be an effective strategy to apply during postdisaster economic reconstruction, and that policies in transportation recovery and in health care are essential for effective postdisaster economic recovery.

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Dabo Guan

University of East Anglia

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H. Schöllnberger

Lovelace Respiratory Research Institute

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Hwong-Wen Ma

National Taiwan University

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Zhu Liu

University of East Anglia

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Edward L. Frome

Oak Ridge National Laboratory

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Randall S. Caswell

National Institute of Standards and Technology

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Mark Syddall

University of Cambridge

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Terry Barker

University of Cambridge

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Carl M. Shy

University of North Carolina at Chapel Hill

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