Dushin Jeong
Soonchunhyang University
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Featured researches published by Dushin Jeong.
Journal of the Neurological Sciences | 2008
Yoon Ho Hong; Seok Beom Kwon; Byung Jo Kim; Byoung Joon Kim; Seung Hyun Kim; Jong Kuk Kim; Kyung Seok Park; Ki Jong Park; Jung Joon Sung; Eun Hee Sohn; Yeong-Bae Lee; Dushin Jeong; In Soo Joo; Byung Ok Choi; Young Chul Choi
OBJECTIVES The aims of this study were to obtain data on the frequency with which Korean patients with autoimmune myasthenia gravis (MG) present solely with ocular disturbances and progress to develop generalized disease and to identify the prognostic factors associated with secondary generalization. METHODS We conducted a retrospective multicenter survey in which a total of 376 adult patients who were newly diagnosed with MG from 2000 through 2005 were reviewed for analysis. Patients with ocular MG at the time of symptom presentation (n=202, 53.7%) were divided into two subgroups according to their prognosis: the patients whose disease remained ocular throughout the follow-ups were placed in the OMG-R group, and the patients who progressed to develop generalized disease were placed in the OMG-G group. Clinical characteristics and laboratory findings were compared between the two subgroups. RESULTS Secondary generalization developed in 47 (23.3%) of the 202 study subjects, mostly within the first 6 months after symptom presentation, while the disease remained ocular throughout the follow-up duration (median 11.8 months) in the remaining 155 patients (76.7%). AChR antibody, abnormal repetitive nerve stimulation tests (RNST) and thymoma were more frequently observed in the patients in the OMG-G group than in those in the OMG-R group (p<0.01 in all). In seropositive cases, the titers of AChR antibody were also significantly higher in the OMG-G group than in the OMG-R group (median, 3.8 nM vs. 6.4 nM; p<0.05). Cox proportional hazards regression analyses showed that early oral prednisolone treatment significantly reduced the risk of secondary generalization (HR, 0.24; 95% CI, 0.11-0.56), whereas abnormal AChR antibody (HR, 5.34; 95% CI, 1.60-17.8) and thymoma (HR, 2.32; 95% CI, 1.21-4.45) were predictive of the development of secondary generalization. CONCLUSIONS Our findings suggest that several factors, including the AChR antibody, thymoma, early corticosteroid treatment, and possibly latent neuromuscular abnormality revealed by RNST, may have an impact on the risk of developing generalized disease in Korean patients presenting with ocular myasthenia.
Journal of the Korean neurological association | 2012
Dong Joo Yun; Jee-Young Oh; Byung Jo Kim; Jeong Geun Lim; Jong Seok Bae; Dushin Jeong; In Soo Joo; Min Su Park; Byoung Joon Kim
Soonchunhyang Medical Science | 2016
Dae-seop Shin; Dushin Jeong; Kwang Ik Yang; Hyung Kook Park; Hyung Geun Oh
Soonchunhyang Medical Science | 2016
Seung Cheol Lee; Dushin Jeong; Kwang Ik Yang; Hyung Kook Park; Hyung Geun Oh
Soonchunhyang Medical Science | 2016
Dae-Seop Shin; Seung Cheol Lee; Doh-Eui Kim; Dushin Jeong
Journal of the Korean neurological association | 2015
Jee Hun Baek; Se Won Oh; Won Kyong Bae; Jai-Joon Shim; Dae Seop Shin; Seung-Chul Lee; Dushin Jeong; Hyung Kook Park; Hyung-Geun Oh
Journal of Korean Sleep Research Society | 2013
Il-Kyo Seo; Yun-Im Choi; Dushin Jeong; Hyung Kook Park; Young Hwangbo; Kwang Ik Yang
T200903781.pdf | 2009
오승헌; 강대룡; 최영철; 최병옥; 김대성; 정두신; 박경석; 문기태; 김승민; 김병준; 임정근; 주인수; 조정희; 김진호; 손은희; 노학재; 김종국; 이영배; 김남희; 서범천; 대한신경근육질환학회; Seung-Hun Oh; Dae-Ryong Kang; Young-Chul Choi; Byung-Ok Choi; Dae-Seong Kim; Dushin Jeong; Kyung-Seok Park; Ki-Tae Moon; Seung Min Kim
Journal of the Korean neurological association | 2008
Ji-Yun Park; Tae-Woong Kim; Hyung-Geun Oh; Kwang-Ik Yang; Hyung-Kook Park; Hakjae Roh; Dushin Jeong
Journal of the Korean neurological association | 2007
Hyung-Geun Oh; Kwang-Ik Yang; Jeong-Ho Park; Kyung-Bok Lee; Dushin Jeong; Hyung-Kook Park