E. Araujo Junior

Intrauterine Zika virus infection and microcephaly: correlation of perinatal imaging and three-dimensional virtual physical models.

*Department of Radiology, Clı́nica de Diagnóstico por Imagem (CPDI), Rio de Janeiro, Brazil; †Department of Arts and Design, Pontifı́cia Universidade Católica (PUC Rio), Rio de Janeiro, Brazil; ‡Department of Obstetrics and Gynecology, Guastalla Civil Hospital, AUSL Reggio Emilia, Reggio Emilia, Italy; §Create Health Clinic, London, UK; ¶Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil

The cross-sectional area of umbilical cord components in normal pregnancy

Objective: To determine the normal cross‐sectional areas of the umbilical vein, umbilical artery, and Wharton jelly in healthy pregnancies, and correlate the obtained values with fetal anthropometric parameters. Methods: A cross‐sectional study was performed with 312 women between the 24th and 39th weeks of a normal pregnancy. The cross‐sectional areas of umbilical cord vessels were measured at the junction of the cord and fetal abdomen, and the values were subtracted from the total cord cross‐sectional area to assess the cross‐sectional area of the Wharton jelly. The anthropometric parameters analyzed were biparietal diameter, head circumference, femur length, and estimated fetal weight, and the Spearman correlation was used to assess the correlation between the cross‐sectional areas of umbilical cord components and fetal anthropometric parameters. A polynomial regression analysis was performed to identify the curves that best adjusted to mean and standard deviation according to gestational age. Results: A statistically significant correlation was observed between the cross‐sectional areas of cord components and fetal anthropometric parameters (P < 0.001) as well as gestational age (P < 0.001). Conclusions: Reference measurements of the cross‐sectional areas of umbilical cord components are important tools in the assessment of fetal growth.

Assessing repeatability of 3D Doppler indices obtained by static 3D and STIC power Doppler: a combinedin-vivo/in-vitroflow phantom study: Static 3D and STIC power Doppler indices

To compare the variability in vascularization flow index (VFI) seen in serial acquisitions obtained using spatiotemporal image correlation (STIC) and using conventional static three‐dimensional (3D) power Doppler (PD), for both in‐vitro and in‐vivo models, and to evaluate whether the curves formed by VFI values obtained from successive ‘frames’ in a STIC dataset are consistent and resemble the waveforms obtained by spectral Doppler analysis.

Effectiveness of vesicoamniotic shunt in fetuses with congenital lower urinary tract obstruction: an updated systematic review and meta-analysis

To evaluate the effect on perinatal and postnatal survival of vesicoamniotic shunt (VAS) as treatment for fetal lower urinary tract obstruction (LUTO).

Reproducibility of first‐ and second‐trimester uterine artery pulsatility index measured by transvaginal and transabdominal ultrasound

To examine and compare the reproducibility of measurement of first‐ and second‐trimester uterine artery pulsatility index (UtA‐PI) using transabdominal (TAS) and transvaginal (TVS) ultrasound.

Congenital heart disease and adverse perinatal outcome in fetuses with confirmed isolated single functioning umbilical artery

Abstract To examine the association between isolated single umbilical artery (SUA) and congenital heart disease/adverse perinatal outcome in an Australian tertiary centre. The study population was comprised of fetuses diagnosed with SUA at the mid-trimester scan between May 2003 and March 2009 during detailed ultrasound examination at The Royal Womens Hospital Melbourne, Australia. Colour Doppler was used to visualise the umbilical arteries adjacent to the fetal bladder and in a section of a free loop of cord. The diagnosis of SUA was confirmed on histopathology examination of the placenta and umbilical cord. Monochorionic twins, fetuses with chromosomal abnormalities or concurrent extracardiac anomalies were excluded from the study. A total of 261 fetuses with SUA were identified in the study period and 146 (59%) cases were isolated; no chromosomal or extracardiac abnormalities were present. Complete data were available in 104/146 pregnancies (71.2%). The mean gestational age at diagnosis was 21 weeks. A cardiac anomaly was detected in 19 of these fetuses (13.0%): six hypoplastic left heart syndromes; three coarctations of the aorta; two tetralogies of Fallot; two hypoplastic right heart syndromes; two pulmonary atresia/stenosis; one absent ductus venosus with cardiomegaly; one left isomerism; one right isomerism and one transposition of the great arteries. Fetal growth restriction was present in 9.8% (10) and preterm delivery before 34 weeks occurred in nine cases (8.7%). Our study has shown that isolated SUA is associated with cardiac anomalies, but is not associated with increased frequency of FGR and preterm delivery before 34 weeks.

Cervical length as a predictor for spontaneous preterm birth in high-risk singleton pregnancy: current knowledge.

†The University of Melbourne, Department of Obstetrics and Gynaecology, The Royal Women’s Hospital, Locked Bag 300, Parkville, Victoria 3052, Australia; ‡Pregnancy Research Centre, Department of Maternal-Fetal Medicine, The Royal Women’s Hospital, Parkville, Victoria, Australia; §Department of Obstetrics, Paulista School of Medicine Federal University of São Paulo, São Paulo, Brazil *Correspondence. (e-mail: Fabricio.Costa@thewomens.org.au)

Perinatal outcomes and intrauterine complications following fetal intervention for congenital heart disease: systematic review and meta-analysis of observational studies.

To assess perinatal outcomes and intrauterine complications following fetal intervention for congenital heart disease (CHD).

Monochorionic diamniotic quadruplet pregnancy: physical models from prenatal three‐dimensional ultrasound and magnetic resonance imaging data

H. WERNER1, P. CASTRO1, P. DALTRO1, J. LOPES DOS SANTOS2, G. RIBEIRO2, G. TONNI3, S. CAMPBELL4 and E. ARAUJO JÚNIOR5 1Department of Radiology, Clı́nica de Diagnóstico por Imagem (CDPI), Rio de Janeiro, Brazil; 2Department of Arts and Design, Pontifı́cia Universidade Católica (PUC Rio), Rio de Janeiro, Brazil; 3Department of Obstetrics and Gynecology, Guastalla Civil Hospital, AUSL Reggio Emilia, Italy; 4Create Health Clinic, London, UK; 5Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil

P09.15: Three‐dimensional sonographic volumetry of phantom objects: comparing rotational method Virtual Organ Computer‐aided AnaLysis (VOCAL) to multi slice method Extended Imaging (XI) VOCAL

obtain the values of EV: XI VOCAL method. Using a sequential section, the contour of each gestational embryo was drawn manually in the fifteen different rotation planes to obtain the 3D volume measurement. To evaluate the relation between EV and gestational age (GA), Person’s correlation coefficient (r) was used. The paired Student’s t-test (P) and ANOVA were used to compare the methods. Results: The study showed there was correlation between EV and GA (r = 0.83 for VOCAL 30 degrees, r = 0.83 for XI VOCAL and r = 0.80 for multiplanar). There was a strong correlation between EV measured by the XI VOCAL e multiplanar methods (RICC = 0,941) and XI VOCAL and VOCAL methods (RICC= 0,965). There weren’t difference statistics between EV measured by the VOCAL, XI VOCAL and the multiplanar by the paired Student’s t-test, but ANOVA showed differences between all methods (p < 0.001). Conclusion: We have demonstrated a strong correlation with the age gestational and embryo volume measurements obtained using the XI VOCAL, VOCAL and multiplanar methods in first trimester gestational. The methods were concordant, but there were differences statistics.