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Featured researches published by E. B. Hughes.


Nuclear Instruments and Methods in Physics Research | 1984

Computed tomography using synchrotron radiation

A.C. Thompson; J. Llacer; L. Campbell Finman; E. B. Hughes; J. N. Otis; S. Wilson; H. D. Zeman

Abstract X-ray computed tomography (CT) is a widely used method of obtaining cross sectional views of objects. The high intensity, natural collimation, monochromaticity and energy tunability of synchrotron X-ray sources could potentially be used to provide CT images of improved quality. The advantages of these systems would be that images could be produced more rapidly with better spatial resolution and reduced beam artifacts. In addition images, in some cases, could be acquired with elemental sensitivity. As a demonstration of the capability of such a system, CT images were obtained of four slices of an excised pig heart, in which the arteries and cardiac chambers were filled with an iodinated medium. Images were taken with incident X-rays tuned successively to energies just above and below the iodine K edge. Iodine specific images were obtained by logarithmically subtracting the low energy image data from the high energy data and then reconstructing the image. CT imaging using synchrotron radiation may become a convenient and non-destructive method of imaging samples difficult to study by other methods.


Nuclear Instruments and Methods | 1979

Inorganic scintillators: A review of techniques and applications

R.L. Heath; R. Hofstadter; E. B. Hughes

Abstract A review of techniques used in the production and operation of NaI(Tl) detectors is provided. The scintillation mechanism itself is summarized, and examples of the use of NaI(Tl) detectors is several areas of science and technology are given.


Conference on Digital Rdiography | 1981

Synchrotron Radiation And Its Application To Digital Subtraction Angiography

E. R ubenstein; E. B. Hughes; L. E. Campbell; R. Hofstadter; R. L. Kirk; T. J. Krolicki; J. P. Stone; S. Wilson; H. D. Zeman; W. R. Brody; A.C. Thompson

The intense synchrotron radiation produced at electron storage rings provides a new source of X-rays highly suited to iodine K-edge digital subtraction angiography. The high intensity and small angular divergence permit the radiation to be monochromatized by Bragg diffraction and made available in beams of small vertical size, of arbitrary horizontal width, and of tunable energy. The use of such beams provides maximum sensitivity to intra-arterial iodine and virtually eliminates image contrast due to non-vascular body structures. The sensitivity of this method to iodine offers the prospect of visualizing arteries by peripheral venous injection.


Physical Review Letters | 1986

Search for the decay micro+-->e+ gamma.

Richard D. Bolton; J. D. Bowman; Cooper; J. S. Frank; A.L. Hallin; P.A. Heusi; C. M. Hoffman; G. E. Hogan; F. G. Mariam; Howard S. Matis; R. E. Mischke; D. E. Nagle; Leo Piilonen; V. Sandberg; Gary H. Sanders; U. Sennhauser; R. Werbeck; Russell A. Williams; S.L. Wilson; R. Hofstadter; E. B. Hughes; M.W. Ritter; D. Grosnick; S.C. Wright; V.L. Highland; J. McDonough

This Letter reports a new experimental search for the family-number-nonconserving decay ..mu../sup +/ ..-->.. e/sup +/..gamma... There is no evidence for the presence of this decay mode. The upper limit for the branching ratio is GAMMA(..mu.. ..-->.. e..gamma..)/GAMMA(..mu.. ..-->.. enu anti nu) < 4.9 x 10/sup -11/ (90% C.L.). 13 refs., 3 figs.


Nuclear Instruments and Methods in Physics Research | 1983

The application of synchrotron radiation to non-invasive angiography☆

E. B. Hughes; H. D. Zeman; L. E. Campbell; R. Hofstadter; U. Meyer-Berkhout; J. N. Otis; J. Rolfe; J. P. Stone; S. Wilson; Edward Rubenstein; Donald C. Harrison; Robert S. Kernoff; A.C. Thompson; George Brown

Abstract Synchrotron radiation provides a new source of X-rays highly-suited to iodine K-edge Digital Subtraction Angiography (DSA). The use of such beams provides maximum sensitivity to intra-arterial iodine and virtually eliminates image contrast due to non-vascular body structures. The intensity of the beams permits short exposure times and allows images to be recorded, in line-scan fashion, in sharp focus despite arterial motions. The sensitivity of this method offers the prospect of visualizing arteries, and in particular the coronary arteries, by peripheral venous injection. The principles of DSA have been demonstrated using phantoms and excised animal hearts, and in vivo studies in animals have begun. The instrumentation developed for this purpose and the results obtained to date are summarized.


Space Science Reviews | 1989

The project EGRET (energetic gamma-ray experiment telescope) on NASA's Gamma-Ray Observatory GRO

G. Kanbach; D. L. Bertsch; A. J. Favale; C. E. Fichtel; R. C. Hartman; R. Hofstadter; E. B. Hughes; Stanley D. Hunter; B.W. Hughlock; D. A. Kniffen; Y. C. Lin; H. A. Mayer-Hasselwander; P. L. Nolan; K. Pinkau; H. Rothermel; Edward J. Schneid; M. Sommer; D. J. Thompson

The Gamma Ray Observatory (GRO) is currently planned for a launch from the space shuttle in 1990. After the long hiatus in high-energy gamma-ray astronomy since the end of the COS-B mission in 1982, the Soviet missions Granat and Gamma-1 and the NASA mission GRO will resume observations in the energy range from below 100 keV and extending to above 10 GeV. GRO will carry four instruments designed to cover this range of over five decades in photon energy. It is planned to perform a complete sky survey above 1 MeV in the first year of the GRO mission. Data from this survey will be used to study galactic and extragalactic sources of gamma radiation as well as the galactic and extragalactic diffuse emissions. Additionally, measurements of gamma ray bursts will be performed. The angular and spectral resolution of the GRO instruments is significantly improved with respect to previous experiments. The sensitivity for point sources will be better by an order of magnitude, and the location of strong, high energy sources will be determined to about 0.1°–0.2°. After a brief description of the complement of GRO instruments, a detailed discussion of the high-energy telescope EGRET, its design and scientific objectives, is presented in this review.


IEEE Transactions on Nuclear Science | 1986

300-Element Silicon-Lithium Position-Sensitive Imaging Detector for Angiography

J.T. Walton; H. A. Sommer; A.C. Thompson; E. B. Hughes; H. D. Zeman

Silicon lithium-drifted [Si(Li)] detectors 150 mm long, 10 mm wide and 5 mm thick with 300 individual elements have been fabricated as imaging detectors for noninvasive studies of human coronary arteries using 33 keV x-rays from a synchrotron radiation beamline. This detector is an extension of earlier work on 30 mm long devices with initially 30 and later 60 elements. The detector fabrication details are discussed highlighting problems in uniform lithium-ion compensation. The device structure is examined and measurements on the interelement impedances presented. Finally an angiograph of the coronary arteries in an excised pigs heart obtained with this 300-element detector is presented.


Nuclear Instruments and Methods | 1969

On the design of NaI(Tl) total absorption detectors for strongly interacting particles at GeV energies

E. B. Hughes; R. Hofstadter; W.L. Lakin; I. Sick

Abstract The properties of a large NaI(Tl) detector as a total absorption detector for pions at GeV energies are reported. These observations are supplemented by measurements on the three-dimensional distribution of deposited energy in a large absorber of metallic tin by GeV pions. The latter data are compared with existing Monte Carlo calculations of the nucleon-meson cascade and their application to the design of total absorption detectors with large containment factors is discussed.


Nuclear Instruments and Methods | 1979

On the detection of 50 MeV γ-rays with a large modularized NaI(Tl) detector☆

R.L. Carrington; R.A. Eichler; R. Hofstadter; E. B. Hughes; J. Rolfe; T.P. McPharlin; J.D. Bowman; M.D. Cooper; M.E. Hamm; C. M. Hoffman; R.E. Mischke; D.E. Nagle; J.S. Sarracino; P.A. Thompson; H. L. Anderson; W.W. Kinnison; H.S. Matis; S.C. Wright

Abstract An array of 45 NaI(Tl) crystals modules, each in 20 in. in length and hexagonal in cross section with six 3 in. sides, has been operated as a detector of 50 MeV γ-rays in a search for the decay μ + →e + γ . The calibration procedure used for this detector and the resolutions achieved in γ-ray energy, time of detection and point of impact on the detector face are described.


IEEE Transactions on Nuclear Science | 1978

Design and Performance of a Modularized NaI(Tl) Detector (The Crystal Ball Prototype)

Y. Chan; R. A. Partridge; C. W. Peck; W. Kollman; M. Richardson; Karl Strauch; D. Aschman; D. G. Coyne; B. L. Beron; R. L. Carrington; R. Eichler; R. Hofstadter; E. B. Hughes; G. I. Kirkbride; A. Liberman; J. O'Reilly; R. Parks; J. Rolfe; J.W. Simpson; J. Tompkins; A. Baumgarten; J. Bernstein; Elliott D. Bloom; F. Bulos; J. Dillon; J. Gaiser; G. L. Godfrey; J. Hall; C. Kiesling; M. Oreglia

A prototye NaI(Tl) detector (the Cluster of 54) of spherical geometry subtending a solid angle of 7.5% of 4¿ at its center, has recently been assembled and tested. This detector consisted of 54 close-packed but optically isolated NaI(Tl) modules and the associated electronic circuitry. The Cluster of 54 is the predecessor of an almost complete spherical detector, the Crystal Ball, which will cover 94% of 4¿. The latter detector is now under construction and is especially designed for the study of ¿-rays produced in electron-positron collisions at colliding beam facilities. This article will outline the mechanical, optical, and electronic assembly of the prototype system. Cluster of 54 test data will be presented.

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C. M. Hoffman

Los Alamos National Laboratory

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R. E. Mischke

Los Alamos National Laboratory

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Howard S. Matis

United States Department of Energy

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A.C. Thompson

Lawrence Berkeley National Laboratory

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