E. Bruce Toby

Osteocutaneous radial forearm free flaps. The necessity of internal fixation of the donor-site defect to prevent pathological fracture.

Background: Osteocutaneous radial forearm free flaps have fallen from favor due to pathological fractures of the radius. The purposes of this study were to propose a means to decrease the rate of pathological fracture by prophylactic fixation of the donor-site defect and to evaluate this technique biomechanically. Methods: Two groups of ten matched pairs of fresh-frozen cadaveric radii were harvested. In Group 1, an eight-centimeter length of radius comprising 50 percent of the cross-sectional area of the bone was removed to simulate an osteocutaneous radial forearm donor-site defect. This defect was created in one member of each pair, with the other bone in the pair left intact. In Group 2, both members of the ten matched pairs of radii had identical defects created as previously described. However, one radius in each pair had a twelve-hole, 3.5-millimeter dynamic compression plate placed across the segmental defect. In each group, five matched pairs were tested to failure in torsion and five matched pairs were tested to failure in four-point bending. Results: In Group 1, the intact radius was a mean of 5.7 times stronger in torsion and 4.2 times stronger in four-point bending than the radius with the segmental resection. In Group 2, the radius that was ostectomized and fixed with a plate was a mean of 4.0 times stronger in torsion and 2.7 times stronger in four-point bending than the ostectomized radius. Conclusions: Removal of an eight-centimeter segment from the radius dramatically decreased both torsion and bending strength. Application of a plate over the defect in the radius significantly restored the strength of the radius (p = 0.01). Clinical Relevance: The segmental defect created in the radius when an osteocutaneous radial forearm free flap is harvested weakens the donor bone an unacceptable amount, resulting in a high risk of pathological fracture. We believe that prophylactic internal fixation of the donor-site defect with a plate restores strength to such a level that pathological fracture may be prevented, thus increasing the utility of the osteocutaneous radial forearm free flap.

Incidental Guyon's canal release during attempted endoscopic carpal tunnel release: An anatomical study and report of two cases

Two patients were found to have a partial release of Guyons canal after attempted endoscopic carpal tunnel release. This resulted in significant morbidity from ulnar nerve injury and required open neurolysis of the ulnar nerve and carpal tunnel release. In order to determine how this error could be made, we performed an endoscopic carpal tunnel release on two cadaveric specimens with subsequent dissection, and found that Guyons canal could be entered with relative ease through the standard portals. If, however, one is aware of this potential complication, uses the ulnar bursa overlying the flexor tendons as a guide, and makes a positive identification of the transverse fibers of the transverse carpal ligament, this mistake can be avoided.

Preoperative evaluation of the radial forearm free flap patient with the objective Allen's test

OBJECTIVE: The conventional subjective Allens test (SAT) can be problematic because of its subjective nature. The objective Allens test (OAT) was used before surgery to reliably and objectively assess forearm vascular flow in anticipation of harvesting a radial forearm free flap (RFFF) for use in head and neck reconstruction. STUDY DESIGN AND SETTING: Retrospective analysis of 65 patients undergoing both preoperative SAT and OAT was completed at the University of Kansas Medical Center between December 1994 and March 1998. RESULTS: The sensitivity and specificity of the SAT compared with the sensitivity and specificity of the OAT were only 65% and 76%, respectively. In 40 patients with at least 1 forearm with a positive SAT, only 1 (2.5%) patient was found by OAT to have vasculature that would not have allowed safe RFFF harvest in either forearm. In contrast, of the 25 patients with equivocal or negative SAT results in both arms, 18 (72%) were found by OAT to be safe candidates for RFFF harvests. CONCLUSIONS: The OAT is an objective measure of forearm vascular flow and is superior to conventional SAT in RFFF donor-site selection.

Fracture-Dislocation of the Humerus with Intrathoracic Displacement of the Humeral Head. A Case Report*

Of the glenohumeral fracture-dislocations that have been described in the orthopaedic literature, those involving intrathoracic displacement of the humeral head are the least common3. We describe here the case of an adolescent patient who sustained a fracture-dislocation of the proximal part of the humerus with intrathoracic displacement of the humeral head when she was struck by a motor vehicle. A fourteen-year-old girl was running across the road when she was struck on her left side by a motor vehicle that was traveling at a speed of approximately thirty-five miles (fifty-six kilometers) per hour. She was thrown about twenty feet (six meters) and landed on her right side. When she was seen in the emergency department at the University of Kansas Medical Center, she had pain in the right shoulder and upper extremity and she resisted attempts to move the extremity. The vital signs included a pulse of seventy-two beats per minute, a blood pressure of 130/70 millimeters of mercury (17.33/9.33 kilopascals), a temperature of 36.6 degrees Celsius, and a respiratory rate of eighteen breaths per minute. Physical examination revealed the right arm to be rigidly held in 80 degrees of abduction and 70 degrees of internal rotation. The proximal portion of the upper extremity appeared to be foreshortened. There was no neurovascular deficit, and the skin was intact. The lungs were clear on auscultation. The patient was also found to have a minimally displaced fracture of the tibial plateau. Physical examination was difficult because the patient was combative and obese. An anteroposterior radiograph of the chest, made with portable equipment, was interpreted as demonstrating a posterior subscapular glenohumeral dislocation …

Torsional strength of the radius after osteofasciocutaneous free flap harvest with and without primary bone plating.

The osteocutaneous radial forearm free flap (OCRFFF) has not gained widespread popularity in mandibular reconstruction, primarily because of concerns about pathologic fracture of the weakened radius. This study examines the effectiveness of plate fixation of the radius bone after harvest of the OCRFFF as a mechanism to minimize donor-site morbidity and increase the usefulness of the OCRFFF. Matched pairs of fresh human cadaveric radius bones were used in this study. Two study groups were designed. The first group was used to define the amount of strength lost after a typical bone graft harvest. The second group was designed to demonstrate how much torsional strength was regained by the application of an orthopedic reconstruction plate. Statistically significant results were obtained for both groups. In group 1, the strength of the cut bones compared with that of the unaltered bones was significantly decreased by 82% (P = 0.016). In group 2, the cut bones reinforced with a plate were 75% stronger (P = 0.002) than the bones that were only cut. Although the radius bone is significantly weakened by the harvest of a graft, much of this strength can be regained with plate fixation of the radius. (Otolaryngol Head Neck Surg 2000; 123:400-8.)

Preventive Effects of Eccentric Training on Acute Hamstring Muscle Injury in Professional Baseball.

Background: Hamstring injuries are the second most common injury causing missed days in professional baseball field players. Recent studies have shown the preventive benefit of eccentric conditioning on the hamstring muscle group in injury prevention. Specifically, Nordic-type exercises have been shown to decrease the incidence of acute hamstring injuries in professional athletes. Purpose: This was a prospective study performed in coordination with a single Major League Baseball (MLB) organization (major and minor league teams) that targeted the effects of Nordic exercises on the incidence of acute hamstring injuries in the professional-level baseball player. Study Design: Prospective cohort study; Level of evidence, 2. Methods: The daily workouts of 283 professional baseball players throughout all levels of a single MLB organization were prospectively recorded. The intervention group participated in the Nordic exercise program and was compared with a randomly selected control group of professional athletes within the organization not participating in the exercise program. The incidence of hamstring injuries in both groups was compared, and the total number of days missed due to injury was compared with the 2 previous seasons. Results: There were 10 hamstring injuries that occurred during the 2012 season among the 283 professional athletes that required removal from play. There were no injuries that occurred in the intervention group (n = 65, 0.00%; P = .0381). The number needed to treat (NNT) to prevent 1 hamstring injury was 11.3. The average repetitions per week of the injured group were assessed at multiple time points (2, 4, 6, and total weeks) prior to injury. There were significantly fewer repetitions per week performed in the injured group at all time points compared with overall average repetitions per week in the noninjured group (P = .0459, .0127, .0164, and .0299, respectively). After beginning the Nordic exercise program, there were 136 total days missed due to a hamstring injury during the 2012 season. This number was less than the 2011 season (273 days missed) and the 2010 season (309 days missed). Conclusion: Study results indicate the initiation of Nordic hamstring exercises may decrease the incidence of acute hamstring injuries and potentially decrease the total number of days missed due to injury in professional baseball players. Clinical Relevance: The financial and competitive interest in professional baseball players is of large importance to the player, team, and fans. Prevention of injuries is as important to all parties involved as the treatment and rehabilitation following an injury. This prospective study shows the initiation of a simple, free exercise can reduce the incidence of hamstring injury in the professional-level baseball player.

MRI-Based Modeling for Radiocarpal Joint Mechanics: Validation Criteria and Results for Four Specimen-Specific Models

The objective of this study was to validate the MRI-based joint contact modeling methodology in the radiocarpal joints by comparison of model results with invasive specimen-specific radiocarpal contact measurements from four cadaver experiments. We used a single validation criterion for multiple outcome measures to characterize the utility and overall validity of the modeling approach. For each experiment, a Pressurex film and a Tekscan sensor were sequentially placed into the radiocarpal joints during simulated grasp. Computer models were constructed based on MRI visualization of the cadaver specimens without load. Images were also acquired during the loaded configuration used with the direct experimental measurements. Geometric surface models of the radius, scaphoid and lunate (including cartilage) were constructed from the images acquired without the load. The carpal bone motions from the unloaded state to the loaded state were determined using a series of 3D image registrations. Cartilage thickness was assumed uniform at 1.0 mm with an effective compressive modulus of 4 MPa. Validation was based on experimental versus model contact area, contact force, average contact pressure and peak contact pressure for the radioscaphoid and radiolunate articulations. Contact area was also measured directly from images acquired under load and compared to the experimental and model data. Qualitatively, there was good correspondence between the MRI-based model data and experimental data, with consistent relative size, shape and location of radioscaphoid and radiolunate contact regions. Quantitative data from the model generally compared well with the experimental data for all specimens. Contact area from the MRI-based model was very similar to the contact area measured directly from the images. For all outcome measures except average and peak pressures, at least two specimen models met the validation criteria with respect to experimental measurements for both articulations. Only the model for one specimen met the validation criteria for average and peak pressure of both articulations; however the experimental measures for peak pressure also exhibited high variability. MRI-based modeling can reliably be used for evaluating the contact area and contact force with similar confidence as in currently available experimental techniques. Average contact pressure, and peak contact pressure were more variable from all measurement techniques, and these measures from MRI-based modeling should be used with some caution.

Scapholunate ligament injury adversely alters in vivo wrist joint mechanics: an MRI-based modeling study.

We investigated the effects of scapholunate ligament injury on in vivo radiocarpal joint mechanics using image‐based surface contact modeling. Magnetic resonance images of 10 injured and contralateral normal wrists were acquired at high resolution (hand relaxed) and during functional grasp. Three‐dimensional surface models of the radioscaphoid and radiolunate articulations were constructed from the relaxed images, and image registration between the relaxed and grasp images provided kinematics. The displacement driven models were implemented in contact modeling software. Contact parameters were determined from interpenetration of interacting bodies and a linear contact rule. Peak and mean contact pressures, contact forces and contact areas were compared between the normal and injured wrists. Also measured were effective (direct) contact areas and intercentroid distances from the grasp images. Means of the model contact areas were within 10 mm2 of the direct contact areas for both articulations. With injury, all contact parameters significantly increased in the radioscaphoid articulation, while only peak contact pressure and contact force significantly increased in the radiolunate articulation. Intercentroid distances also increased significantly with injury. This study provides novel in vivo contact mechanics data from scapholunate ligament injury and confirms detrimental alterations as a result of injury.

PRELIMINARY VALIDATION OF MRI-BASED MODELING FOR EVALUATION OF JOINT MECHANICS

The objective of this study was to perform preliminary validation of MRI-based joint contact modeling methodology in the radiocarpal joints by comparison with the results of invasive radiocarpal contact measurements in three cadaver experiments. For each experiment, either Pressurex film or a Tekscan sensor was placed into the radiocarpal joints during a simulated grasp. Computer models were based on magnetic resonance imaging (MRI) of the cadaver specimens without load as well as on images acquired with the same loading used for the direct measurements. Geometric surface models of the radius, scaphoid, and lunate (including cartilage) were constructed from the images acquired without load. The carpal bone motions from the unloaded to the loaded state were determined using three-dimensional (3D) voxel image registration. Cartilage thickness was assumed to be uniform at 1.0 mm with an effective compressive modulus of 4 MPa. Resulting data included peak contact pressure, contact area, and contact force in the radioscaphoid and radiolunate joints. Contact area was also measured directly from MR images acquired with load and compared to model data. Qualitatively, there was good correspondence between the MRI-based model data and experimental data, with consistent relative size, shape, and location of radioscaphoid and radiolunate contact areas. Quantitative comparison of model and experimental data was reasonable, but less consistent. Contact area from the MRI-based model was always similar to the contact area measured directly from the MR images. With additional experiments, we believe that MRI-based joint contact modeling will soon be fully validated in the radiocarpal joints.

Computationally Efficient Magnetic Resonance Imaging Based Surface Contact Modeling as a Tool to Evaluate Joint Injuries and Outcomes of Surgical Interventions Compared to Finite Element Modeling

Joint injuries and the resulting posttraumatic osteoarthritis (OA) are a significant problem. There is still a need for tools to evaluate joint injuries, their effect on joint mechanics, and the relationship between altered mechanics and OA. Better understanding of injuries and their relationship to OA may aid in the development or refinement of treatment methods. This may be partially achieved by monitoring changes in joint mechanics that are a direct consequence of injury. Techniques such as image-based finite element modeling can provide in vivo joint mechanics data but can also be laborious and computationally expensive. Alternate modeling techniques that can provide similar results in a computationally efficient manner are an attractive prospect. It is likely possible to estimate risk of OA due to injury from surface contact mechanics data alone. The objective of this study was to compare joint contact mechanics from image-based surface contact modeling (SCM) and finite element modeling (FEM) in normal, injured (scapholunate ligament tear), and surgically repaired radiocarpal joints. Since FEM is accepted as the gold standard to evaluate joint contact stresses, our assumption was that results obtained using this method would accurately represent the true value. Magnetic resonance images (MRI) of the normal, injured, and postoperative wrists of three subjects were acquired when relaxed and during functional grasp. Surface and volumetric models of the radiolunate and radioscaphoid articulations were constructed from the relaxed images for SCM and FEM analyses, respectively. Kinematic boundary conditions were acquired from image registration between the relaxed and grasp images. For the SCM technique, a linear contact relationship was used to estimate contact outcomes based on interactions of the rigid articular surfaces in contact. For FEM, a pressure-overclosure relationship was used to estimate outcomes based on deformable body contact interactions. The SCM technique was able to evaluate variations in contact outcomes arising from scapholunate ligament injury and also the effects of surgical repair, with similar accuracy to the FEM gold standard. At least 80% of contact forces, peak contact pressures, mean contact pressures and contact areas from SCM were within 10 N, 0.5 MPa, 0.2 MPa, and 15 mm2, respectively, of the results from FEM, regardless of the state of the wrist. Depending on the application, the MRI-based SCM technique has the potential to provide clinically relevant subject-specific results in a computationally efficient manner compared to FEM.