E. Chiari

Ventricular arrhythmias in normotensive subjects and in mild hypertensive patients

Twenty-five normotensive subjects (14 men, 11 women) aged from 25 to 60 years (mean 36) and 30 untreated patients with mild hypertension (stages 1 and 2, JNC V) without target organ damage (16 men, 14 women), aged 26-59 years (mean 35.8) underwent continuous 24-hour ECG Holter monitoring with a Fukuda Denshi SM-40 ambulatory recorder and SCM-400 ECG analyzer. During 24-hour ambulatory ECG recording, mean heart rate was slightly but not significantly higher in hypertensive patients (73.3 ± 10 beats per minute [bpm]) in comparison with normotensive subjects (71.2 ± 12 bpm). The prevalence of premature atrial contractions was similar in the two groups. Total ventricular arrhythmias were more prevalent in the group of mild hypertensive patients (P<0.05), who also had a higher prevalence in complex forms of ectopy (r=0.81 for bigeminy; r=0.83 for trigeminy; r=0.83 for couplets). Holter recordings did not show abnormalities of ST-T wave or episodes of silent ischemia.