E. Clarence Rice

The treatment of meningitis due to Hemophilus influenzae (Pfeiffer's bacillus)

Summary Meningitis due to H. influenzae is relatively common in children. Excluding tuberculous meningitis, it is the commonest cause of meningitis in children under 2 years of age. The average age in this series of 108 patients was 2.14 years. The treatment of this type of meningitis with specific serum and human complement intrathecally, intravenous serum, with adequate supportive treatment consisting of transfusions, fluids, and vitamins, has reduced the mortality percentage from 97 to 83. By adding sulfanilamide and sulfapyridine to the above, the mortality for thirteen cases has been further reduced to 54 per cent.

Treatment of Meningitis Due to Haemophilus influenzae

THE treatment of meningitis due to Haemophilus influenzae has undergone considerable change in the past fifteen years. Prior to the advent of specific therapy, this disease was fatal in 90 to 100 p...

Alkaligenes fecalis bacteremia and meningitis; report of two cases in newborn infants.

Summary Two additional cases of bacteremia and meningitis due to A. fecalis areadded to the literature. This brings the total to eight. The two cases reported are the first of bacteremia and meningitis caused byA. fecalis in the newborn infant.

Thrombosis of the inferior vena cava and renal veins with hemorrhagic renal infarction in infancy.

Summary A review of the literature on renalvein thrombosis and infarction of the kidneys revealed that this condition usually is a complication of diarrhea in newborn infants, that it is extremely rare, and that its exact etiology is unknown. In the case which has been reported, post-mortem examination showed massive thrombosis, including the inferior vena cava, rolandic veins, and renal veins, with bilateral hemorrhagic renal infarction (Fig. 2). Hypertension in these cases is exceedingly rare, but in this case the blood pressure appeared to be elevated.

PROTAMINE INSULIN AS A CONTRIBUTING FACTOR IN THE DEATH OF A DIABETIC PATIENT WITH CEREBRAL ARTERIOSCLEROSIS

Excerpt Protamine insulin was first used in the United States during 1935 by Root,1Joslin2and their associates and since then its use has been extended to diabetic patients in other parts of the co...

Paper electrophoretic study of serum proteins in children with leukemia

Summary 1. Serum protein analyses by paper electrophoresis on twenty-three children with leukemia have been presented. 2. Normal serum protein patterns were frequently observed. Variations from normal consisted of low albumin and gamma globulin and occasionally an increase in alpha 1 and alpha 2 globulins in patients with acute lymphocytic leukemia. In acute myelogenous leukemia a decrease in the albumin fraction and an increase in alpha 1 and alpha 2 globulins occurred. A low albumin and beta globulin and occasional elevation of the alpha 2 globulin were sometimes seen in patients with chronic myelocytic leukemia. The one patient studied with chronic lymphocytic leukemia showed a normal serum protein pattern. 3. The mean values for each serum protein constituent in each group of leukemia patients studied fell within the normal range; however, wide variations from the mean plus or minus (±) 1.96 standard deviations of the mean were encountered. 4. No direct correlation could be made between the alteration of serum protein constituents and the drugs employed in the therapy of these patients except for a decrease in the albumin fraction during steroid therapy. 5. Alterations in the normal serum protein fractions in patients with leukemia is probably of a nonspecific nature and may be related to tissue destruction, fever, or infection. 6. Changes in the electrophoretic serum protein components in the present study were of little value in the diagnosis of leukemia; however, the presence of abnormal patterns may lead one to suspect a relapse and progression of the disease.

Truncus arteriosus communis persistens: A report of three cases

Summary 1. Three cases of truncus arteriosus communis persistens are presented. 2. Hemodynamograms of the circulation as it existed in life are included,with remarks which speculate on the probable mechanism of death.

Original communicationTruncus arteriosus communis persistens: A report of three cases

Summary 1. Three cases of truncus arteriosus communis persistens are presented. 2. Hemodynamograms of the circulation as it existed in life are included,with remarks which speculate on the probable mechanism of death.

Pulmonary gangrene in a child followingaspiration of timothy grass

Summary 1. A case of pulmonary gangrene following aspiration of timothy grass is presented. 2. A discussion of the foreign body and a brief review of the literature isincluded. 3. The pathologic and bacteriologic pattern is briefly discussed.

Anomalous origins of the right common carotid andright and left subclavian arteries associated with eisenmenger's complex

Summary 1. A case of anomalous origins of the right common carotid and right and left subclavian arteries associated with Eisenmengers complex in a Mongolian idiot, is presented. 2. Some embryological considerations are reviewed in an attempt to explain the probable source of the anomalous origins of these vessels. 3. Theoretical considerations of the direction of blood flow are discussed in an attempt to correlate the clinical picture with the anatomical findings.