E. M. Butt

THE INORGANIC ELEMENT CONTENT OF CERTAIN HUMAN TISSUES

Excerpt The purpose of this paper is threefold: first, to point out the average content of certain inorganic elements in human tissues by the study of material from 910 autopsied patients; second, ...

Rapid induction of iron deposition in spleen and liver with an iron-fructose chelate.

Summary The dietary effectiveness of an iron-fructose chelate was compared with FeSO4 using the criteria of total iron analyses and histologic staining technics on liver and spleen of rats. The ferric-fructose was more rapidly absorbed and deposited in the tissues indicating the importance of chelation phenomena in metal transport, and suggesting a molecular basis for Bantu cytosiderosis and experimentally induced iron storage in rats.

Tissue and Serum Manganese Levels in Evaluation of Heart Muscle Damage. A Comparison with SGOT

Summary Whereas, in our series, serum manganese values in patients with congenital, infectious, degenerative, or neoplastic disease were below 1.9 μg/100 ml of serum, serum manganese was elevated above 2.0 μg following acute myocardial infarction in every instance. Massive pulmonary infarction, which also may be accompanied by high serum manganese levels, can be differentiated from myocardial infarction by additional information supplied by serum aluminum values, which are elevated following pulmonary injury but not following myocardial damage. In patients with myocardial infarction, height of the serum manganese level provides an index to extent and severity of cardiac damage as estimated on the basis of SGOT level and the ECG. Although a close correlation exists between SGOT and serum manganese values, our data indicate that serum manganese concentrations are less likely to yield false positive indications of myocardial damage.

Production of Meningoceles and Cranioschisis in Chick Embryos with Lead Nitrate.

Conclusion (1) Injection of lead into the albumen of fertile eggs may result in the production of meningoceles in chick embryos. (2) Copper and mercury ions were noted to be as toxic as similar quantities of the lead ion, but meningoceles were not seen in the embryos surviving 13 days incubation. (3) Sodium salts of anion used in the metal experiments failed to produce meningoceles.