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Dive into the research topics where E. Tsuchida is active.

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Featured researches published by E. Tsuchida.


Artificial Cells, Blood Substitutes, and Biotechnology | 1994

Two types of totally artificial red blood cell substitutes liposome embedded heme(L/H) and lipidheme/microsphere(LHM).

Koichi Kobayashi; T. Kakizaki; Teruyuki Komatsu; Hiroyuki Nishide; E. Tsuchida

Two types of totally artificial oxygen carriers were produced (1)by embedding synthetic lipidhemes (as oxygen carriers) in bilayers of liposomes as vehicles of lipidhemes (L/H) and (2)by covering clinically available fat droplets (triglyceride microspheres) with synthetic lipidhemes (LHM). Fat droplets were used as vehicles of lipidhemes. Their oxygen carrying ability in vivo was examined in beagles undergoing hemorrhagic shock. L/H delivered 15.7 to 19.2% of total oxygen delivery. From 12.7 to 24.4% of total oxygen consumption was from L/H. LHM delivered 11.6 to 7.3% of total oxygen delivery. From 13.1 to 16.4% of total oxygen consumption was from LHM. These totally synthetic red blood cell substitutes can be candidates for future clinical testing.


The Japanese Journal of Artificial Organs | 1993

Preparation conditions of human hemoglobin-vesicles covered with lipid membranes

Shinji Takeoka; Hiromi Sakai; E. Tsuchida; Hiroyuki Nishide


Asaio Journal | 1991

Liposome-embedded-heme as a totally artificial oxygen carrier

Koichi Kobayashi; Masazumi Watanabe; Tsuneo Ishihara; Hiroyuki Nishide; E. Tsuchida


Proceedings of the ACS Division of Polymeric Materials: Science and Engineering | 1989

Facilitated transport of nitrogen and acetylene in poly(vinylcyclopentadienylmanganese) membrane

Hiroyuki Nishide; Hiroyoshi Kawakami; E. Tsuchida


ACS Symp Ser 121, Modif of Polym, based on a symp at the ACS (Am Chem Soc)/CSJ (Chem Soc of Jpn) Chem Congr | 1980

POLYMER-COPPER CATALYSTS FOR OXIDATIVE POLYMERIZATION OF PHENOL DERIVATIVES.

E. Tsuchida; Hiroyuki Nishide


The Japanese Journal of Artificial Organs | 1994

Modification of Hb-vesicles with oligosaccharide chains

Hiromi Sakai; Mikimasa Takisada; Joo Eun Chung; Shinji Takeoka; E. Tsuchida


The Japanese Journal of Artificial Organs | 1994

Suppression of metHb formation in Hb-vesicles by glutathione

Hiroaki Yokohama; Yuriko Seino; Joo Eun Chung; Hiromi Sakai; Shinji Takeoka; Hiroyuki Nishide; E. Tsuchida


Artificial Cells, Blood Substitutes, and Immobilization Biotechnology | 1994

A new totally synthetic oxygen carrier: Lipid heme microshere(LHM)

Koichi Kobayashi; T. Kakizaki; Yoshio Izumi; S. Takeoka; Teruyuki Komatsu; Hiroyuki Nishide; E. Tsuchida


Artificial Cells, Blood Substitutes, and Immobilization Biotechnology | 1994

Two types of totally synthetic oxygen carrier: Liposome embedded heme(L/H) and lipid heme microshere(LH-M)

Koichi Kobayashi; Hiroyuki Nishide; E. Tsuchida


The Japanese Journal of Artificial Organs | 1993

Lipidheme-microsphere (artificial red cell); solution properties and oxygen-transporting ability

Teruyuki Komatsu; Kenji Arai; Noriyuki Kawai; Hiroyuki Nishide; E. Tsuchida; T. Kakizaki; Koichi Kobayashi

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Hiromi Sakai

Nara Medical University

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