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E. Williams

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Publication

Featured researches published by E. Williams.

Archive | 2018

Crystal structure of the kelch domain of human KLHL20 in complex with DAPK1 peptide

Z. Chen; V. Hozjan; C. Strain-Damerell; E. Williams; D. Wang; C.D.O. Cooper; C.E. Sanvitale; M. Fairhead; Elisabeth P. Carpenter; A.C.W. Pike; T. Krojer; V. Srikannathasan; F. Sorrell; C. Johansson; S. Mathea; N. Burgess-Brown; F. von Delft; C.H. Arrowsmith; A. Edwards; C. Bountra; Alex N. Bullock

Archive | 2018

Crystal structure of the ACVR1 (ALK2) kinase in complex with a Quinazolinone based ALK2 inhibitor with a 2, 5-dimethyl core.

E. Williams; L. Hudson; G.A. Bezerra; F. Sorrell; S. Mathea; Z. Chen; P. Mahajan; K. Kupinska; S. Hoelder; N. Burgess-Brown; F. von Delft; C.H. Arrowsmith; A. Edwards; C. Bountra; Alex N. Bullock

Archive | 2018

Crystal structure of the ACVR1 (ALK2) kinase in complex with an Quinazolinone based ALK2 inhibitor with a 4-morpholinophenyl solvent accessible group.

E. Williams; L. Hudson; G.A. Bezerra; J. Kopec; P. Mahajan; K. Kupinska; S. Hoelder; N. Burgess-Brown; F. von Delft; C.H. Arrowsmith; A. Edwards; C. Bountra; Alex N. Bullock

Archive | 2017

Crystal structure of the ACVR1 (ALK2) kinase in complex with LDN-212854

E. Williams; F.J. Sorrell; J. Kopec; R. Nowak; K. Kupinska; F. von Delft; N. Burgess-Brown; C.H. Arrowsmith; A. Edwards; C. Bountra; Alex N. Bullock

Archive | 2017

Crystal structure of the kinase domain of the Q207E mutant of ACVR1 (ALK2) in complex with a 2-aminopyridine inhibitor K02288

E. Williams; P. Canning; C.E. Sanvitale; T. Krojer; C.K. Allerston; F. von Delft; C.H. Arrowsmith; A. Edwards; C. Bountra; Alex N. Bullock

Archive | 2017

Crystal structure of the Pleckstrin homology domain of Interactor protein for cytohesin exchange factors 1 (IPCEF1)

J.A. Newman; H. Aitkenhead; D. Wang; N. Burgess-Brown; E. Williams; F. von Delft; C.H. Arrowsmith; A. Edwards; C. Bountra; O. Gileadi

Archive | 2016

Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution.

S.G. Bartual; D.M. Pinkas; Z. Wang; K. Ding; P. Mahajan; K. Kupinska; S. Mukhopadhyay; C. Strain-Damerell; O. Borkowska; R. Talon; J. Kopec; E. Williams; Cynthia Tallant; A. Chaikuad; F. Sorell; Janet Newman; N. Burgess-Brown; C.H. Arrowsmith; F. von Delft; A. Edwards; C. Bountra; Alex N. Bullock

Archive | 2015

Crystal structure of the BTB domain of human KCTD16

D.M. Pinkas; F. Sorrell; C.E. Sanvitale; S. Goubin; E. Williams; J.A. Newman; N. Pearce; I. Neshich; A.C.W. Pike; A. MacKenzie; A. Quigley; B. Faust; Elisabeth P. Carpenter; Cynthia Tallant; J. Kopec; R. Chalk; T. Krojer; N. Burgess-Brown; F. von Delft; C.H. Arrowsmith; A. Edwards; C. Bountra; Alex N. Bullock

Archive | 2014

Crystal Structure of BMP-2-inducible kinase in complex with baricitinib

F.J. Sorrell; J.M. Elkins; T. Krojer; E. Williams; P. Savitsky; F. von Delft; C.H. Arrowsmith; A. Edwards; C. Bountra; Stefan Knapp

Archive | 2014

Crystal structure of the human KLHL2 Kelch domain in complex with a WNK4 peptide

F.J. Sorrell; F.R. Schumacher; T. Kurz; D.R. Alessi; Janet Newman; S. Goubin; R. Chalk; J. Kopec; Cynthia Tallant; E. Williams; T. Krojer; F. von Delft; C.H. Arrowsmith; A. Edwards; C. Bountra; Alex N. Bullock

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Collaboration

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A. Edwards

University of Toronto

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J.M. Elkins

State University of Campinas

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Stefan Knapp

Goethe University Frankfurt

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C. Johansson

University of Oxford

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D. Wang

University of Oxford

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Janet Newman

Commonwealth Scientific and Industrial Research Organisation

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Daniel Coutandin

Goethe University Frankfurt

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A. Bradley

University of Oxford

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G. Berridge

University of Oxford

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M. Fairhead

University of Oxford

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