Earle M. Chapman

Thyroid Function in Legg–Perthes Disease

CORRIGAN and his associates1 reported that of 35 patients with Legg–Perthes disease studied by their methods none had normal thyroid function. It has long been suspected that some relation existed between Legg–Perthes disease (aseptic necrosis of the head of the femur) and thyroid function, but previously no one could establish evidence of a significant alteration of thyroid function in such patients. Several years ago Albright2 called attention to the fact that changes simulating Legg–Perthes disease could occur in the epiphyses of many bones during juvenile myxedema. Likewise, Jackson, Hanelin and Albright3 emphasized the fact that a single roentgenogram of one .xa0.xa0.