Ector Jaime Ramírez Barba

Tolerance in Renal Transplantation

Tolerance in human transplantation can be defined in two ways [1]. Clinical tolerance (also referred to as clinical operational tolerance [2]) is the survival of a foreign organ or tissue (allogeneic or xenogeneic) in a normal recipient in the absence of immunosuppression [1]. Immune tolerance is the absence of a detectable immune response against a functional organ or tissue in the absence of immunosuppression [1].