Eddy De Vel

The vestibular evoked myogenic potential: A test–retest reliability study

OBJECTIVE The purpose of this study was to evaluate the reliability of the vestibular evoked myogenic potential (VEMP) response in a clinical setting when only a feedback mechanism is available for monitoring background EMG. METHODS Sixty-one healthy subjects participated in the investigation of the within-session reliability, whereas fourteen of them were retested after one week for examination of the between-session reliability. VEMPs were recorded using 500 Hz tone bursts with the subjects in a sitting position and their heads turned away from the test ear to the contralateral shoulder, thereby pushing their chin against the inflatable cuff of a blood pressure manometer, serving as feedback method. RESULTS The feedback method revealed latency and amplitude values comparable to other data in the literature where different test conditions were applied. Excellent reliability with ICC values ranging from 0.78 to 0.96 and CV(ME) values ranging from 4% to 36%, was achieved for P1 and N1 latency, threshold and interpeak amplitude. Good reliability with ICC values of 0.65 and 0.68 and CV(ME) values of 170% and 189%, was obtained for the asymmetry ratio. CONCLUSIONS A unilateral muscle contraction controlled by a feedback mechanism resulted in reliable response parameters, comparable right to left and corresponding to literature data obtained in different test conditions. SIGNIFICANCE The use of a blood pressure manometer as feedback mechanism combined with a meticulously controlled positioning of the head and contraction of the SCM muscle provides a reliable alternative in clinical settings, when the background muscle contraction cannot be measured or software related correction algorithms are not accessible.

Distortion Product Otoacoustic Emissions: A Normative Study

Distortion product otoacoustic emissions (DPOAEs) were quite recently introduced as a new objective auditory screening technique, having a unique potential because of their ability to analyze the micromechanical functions of the cochlea in a frequency-specific way. In 1992, Kemp and Bray released the commercially available Oto-dynamics Analyzer IL092, which enabled investigators and audiological centres to perform DPOAE measurements in different populations, but without any relationship to normative data. The purpose of this study was to describe the normative aspects of 2fl-f2 DPOAEs obtained with the IL092 from 101 normal ears of 101 healthy young adults. The DPOAEs were obtained automatically by means of two data-collection protocols on the IL092 in the form of DP-gram and DP-growth functions. These data were statistically processed to form a normative database which has the potential of serving as a basis for further research aimed at determining the utility of DPOAE testing in evaluating ear pathologyDistortion product otoacoustic emissions (DPOAEs) were quite recently introduced as a new objective auditory screening technique, having a unique potential because of their ability to analyze the micromechanical functions of the cochlea in a frequency-specific way. In 1992, Kemp and Bray released the commercially available Otodynamics Analyzer ILO92, which enabled investigators and audiological centres to perform DPOAE measurements in different populations, but without any relationship to normative data. The purpose of this study was to describe the normative aspects of 2f1-f2 DPOAEs obtained with the ILO92 from 101 normal ears of 101 healthy young adults. The DPOAEs were obtained automatically by means of two data-collection protocols on the ILO92 in the form of DP-gram and DP-growth functions. These data were statistically processed to form a normative database which has the potential of serving as a basis of for further research aimed at determining the utility of DPOAE testing in evaluating ear pathology.

Comparison of the overall intelligibility, articulation, resonance, and voice characteristics between children using cochlear implants and those using bilateral hearing aids: A pilot study

The purpose of this study was to determine and to compare the overall intelligibility, articulation, resonance, and voice characteristics in children using cochlear implants (CI) and children using conventional hearing aids (HA). Nine prelingually deaf children using CI and six children with a prelingual severe hearing loss using HA, were selected to participate. Objective (DSI, nasalance scores) as well as subjective assessment techniques (perceptual evaluations) were used. Both the CI and HA children demonstrated normal vocal quality and resonance but showed the presence of articulation disorders. In the CI children, intelligibility was significantly better compared to the HA children. Significantly more phonetic and phonological disorders were present in the HA children. The results of this study show a poorer intelligibility of the HA children in comparison with the CI children which is probably due to the occurrence of significantly more phonetic and phonological disorders. Future detailed analysis in a larger sample of CI and HA children may help further clarify the issue of speech and voice characteristics and may demonstrate an important prognostic value.

Cochlear implantation in a patient with superficial siderosis of the central nervous system.

Objective To perform an assessment of the viability of cochlear implantation in a patient with superficial siderosis of the brain. Study Design Case review. Setting Tertiary referral center. Patients Patient with superficial siderosis of the brain. Intervention Cochlear implantation. Main Outcome Measures Electrically evoked auditory brainstem responses and fitting strategy for cochlear implant based on patients subjective responses. Results After some time, C levels and T levels showed a pattern comparable with the evoked auditory brainstem responses. Conclusions Bilateral profound hearing loss after superficial siderosis of the brain is no absolute contraindication for implantation. Furthermore, evoked auditory brainstem measurements can potentially guide the fitting process of the implant in difficult cases.

Characteristics and determinants of music appreciation in adult CI users.

The main objective of this study was to assess the associations between self-reported listening habits and perception of music and speech perception outcomes in quiet and noise for both unilateral cochlear implant (CI) users and bimodal (CI in one ear, hearing aid in contra-lateral ear) users. Information concerning music appreciation was gathered by means of a newly developed questionnaire. Moreover, audiological data (pure-tone audiometry, speech tests in noise and quiet) were gathered and the relationship between speech perception and music appreciation is studied. Bimodal users enjoy listening to music more in comparison with unilateral CI users. Also, music training within rehabilitation is still uncommon, while CI recipients believe that music training might be helpful to maximize their potential with current CI technology. Music training should not be exclusively reserved for the good speech performers. Therefore, a music training program (MTP) that consists of different difficulty levels should be developed. Hopefully, early implementation of MTP in rehabilitation programs can enable adult CI users to enjoy and appreciate music and to maximize their potential with commercially available technology. Furthermore, because bimodal users consider the bimodal stimulation to be the most enjoyable way to listen to music, CI users with residual hearing in the contra-lateral ear should be encouraged to continue wearing their hearing aid in that ear.

Distortion product otoacoustic emissions: An objective technique for the screening of hearing loss in children treated with platin derivatives

In order to develop a sensitive audiometric protocol for identifying ototoxicity in children, a retrospective study of 16 children treated with cisplatin and/or carboplatin was performed. Audiometric testing was done by means of pure-tone threshold audiometry (PTA), high-frequency audiometry (HFA), and distortion product otoacoustic emissions (DPOAEs). Cisplatin caused a sensorineural high-frequency hearing loss in the study group compared to the controls (p < 0.01). Sixty-six percent of the cisplatin patients had a grade 2 or 3 ototoxicity. However, ototoxicity was not found in the patients treated with carboplatin. An excellent correlation was found between DPOAE levels and results obtained by audiometry (r = 0.82). Patients exposed to cisplatin are at significant risk for the development of drug-induced sensorineural hearing loss. Because of the several advantages of DPOAEs (noninvasive, objective, rapid, easy to use, sensitive) this method should be added in the audiological follow-up in infants and toddlers.

Mechanisms in noise-induced permanent hearing loss: an evoked otoacoustic emission and auditory brainstem response study.

In this study 22 patients (44 ears) with noise-induced permanent hearing loss were audiologically evaluated using transient-evoked otoacoustic emissions (TEOAE) and auditory brain-stem response (ABR). Twenty-one normal subjects (42 ears) without exposure to occupational noise were used as controls. Based upon the hearing loss at 4, 3, 2 and 1 kHz on the pure-tone audiogram, they were classified into four groups. In group 1 (eight ears), emissions were present in all ears but their TEOAE-noise level and their reproducibility (percentage) proved to be weak. The auditory brain-stem response (ABR) indicated that the I/V amplitude ratio, the latency values of wave V and the I-V intervals fell within the normal range in all ears. In Group 2 (14 ears), 40 per cent had no emissions, whereas the remaining ears showed weak emissions. The ABR revealed that in all ears the I/V amplitude ratio became small while wave V peak latency as well as I-V intervals were within the normal range. In Group 3 (10 ears), emissions were absent in 50 per cent, while in the other ears the emissions were very weak. The ABR revealed that the I/V amplitude ratio, which could be calculated in the 60 per cent in which wave I was present, was smaller than in Group 2. Wave V latency as well as I-V intervals were within the normal range. In Group 4 (12 ears), none of the ears showed emissions. The ABR indicated that the I/V amplitude ratio was much smaller when wave I was present (27 per cent) as well as I-V interval values being within the normal range. Wave V absolute latency value (delta V index) indicated a positive index in 17 per cent of this group (two ears) when wave I was absent. In the present study a dynamic process from cochlear outer hair cells to cochlear neurons was seen, correlating with an increasing hearing loss.

Binaural interaction in the auditory brainstem response: A normative study

OBJECTIVE Binaural interaction can be investigated using auditory evoked potentials. A binaural interaction component can be derived from the auditory brainstem response (ABR-BIC) and is considered evidence for binaural interaction at the level of the brainstem. Although click ABR-BIC has been investigated thoroughly, data on 500 Hz tone-burst (TB) ABR-BICs are scarce. In this study, characteristics of click and 500 Hz TB ABR-BICs are described. Furthermore, reliability of both click and 500 Hz TB ABR-BIC are investigated. METHODS Eighteen normal hearing young adults (eight women, ten men) were included. ABRs were recorded in response to clicks and 500 Hz TBs. ABR-BICs were derived by subtracting the binaural response from the sum of the monaural responses measured in opposite ears. RESULTS Good inter-rater reliability is obtained for both click and 500 Hz TB ABR-BICs. The most reliable peak in click ABR-BIC occurs at a mean latency of 6.06 ms (SD 0.354 ms). Reliable 500 Hz TB ABR-BIC are obtained with a mean latency of 9.47 ms (SD 0.678 ms). Amplitudes are larger for 500 Hz TB ABR-BIC than for clicks. CONCLUSION The most reliable peak in click ABR-BIC occurs at the downslope of wave V. Five hundred Hertz TB ABR-BIC is characterized by a broad positivity occurring at the level of wave V. SIGNIFICANCE The ABR-BIC is a useful technique to investigate binaural interaction in certain populations. Examples are bilateral hearing aid users, bilateral cochlear implant users and bimodal listeners. The latter refers to the combination of unilateral cochlear implantation and contralateral residual hearing. The majority of these patients have residual hearing in the low frequencies. The current study suggests that 500 Hz TB ABR-BIC may be a suitable technique to assess binaural interaction in this specific population of cochlear implant users.

Audiovisual speech reception in noise and self-perceived hearing disability in sensorineural hearing loss.

Multiple regression analyses were performed on a corpus of data from 56 sensorineurally hearing-impaired subjects. In addition to tonal thresholds, the corpus included simple, quantitative self-ratings for disability and results from speech reception tasks in auditory-only, audiovisual, quiet and noisy conditions. The aim was to evaluate to what extent the predictive power of disability formulas based on the audiogram can be enhanced, when measures derived from speech reception tasks are added to tonal thresholds as supplementary predictors. The better-ear speech reception threshold proved to be a strong exclusive predictor: if speech reception thresholds were introduced into the prediction, the contribution of better-ear pure-tone averages became redundant. Speechreading ability always significantly enhanced the predictions accuracy. Tonal thresholds or speech reception data combined with lipreading ability scores can explain considerable amounts (42 per cent and 54 per cent, respectively) of the variance in disability ratings. The conclusion is that auditory-only, audiogram-based prediction schemes must not be abandoned, but can be tailored to individuals on the basis of realistic audiovisual speech reception performance.

Masking Effects and Tinnitus as Explanatory Variables in Hearing Disability

In cases of substantial auditory handicap, the degree of pure-tone hearing loss or hearing loss for speech is seen as the primary determining factor. Sometimes the presence of tinnitus complaints and disproportionate masking effects of noise on speech reception are seen as aggravating factors. To investigate the relevance of tinnitus and masking effects in the context of hearing disability, four factorial designs with self-perceived hearing disability as the dependent variable were submitted to an analysis of variance. Impact of masking and tinnitus complaints were treated as independent variables with two levels and were each combined with a second independent variable to form a 2 x 2 fixed factor statistical model. This second independent variable was either hearing loss for pure tones (first and second model) or speech reception ability (third and fourth model). Both hearing loss for pure tones and speech reception capability were found to be significant explanatory factors for hearing disability. Impact of masking, if juxtaposed to average pure-tone hearing loss (first model), also came out of the analysis as a significant factor in hearing disability, whereas the tinnitus factor did not reach significance levels. No significant interactions between factors were found. The results support the idea of the differentiating audiogram-based disability estimates by taking noise susceptibility into account. The findings also suggest in an equivocal relation of tinnitus with hearing disability, which prevents it from being a straightforward disability predictor.