Éder Paulo Belato Alves

Efeitos da corrida em esteira em músculos sóleos de ratos encurtados por imobilização

The aim of this work was to compare weight and length adaptations of the soleus muscle of male Wistar rats as well as estimation of the total number of serial sarcomere and mean sarcomere length, when they are submitted to remobilization on treadmill. 18 Wistar male rats were used and divided in the three following groups: CG - left soleus (LS) muscle immobilized and remobilized free in the cage; G10 - LS muscle immobilized and remobilized in speed of 10 m/min on treadmill; and G12 - LS muscle immobilized and remobilized in speed of 12 m/min. The right muscles (RS) of each animal were used for comparison. The results showed the following variations, muscular weigh: CG -22.35% (p = 0.0089), G10 -12.52% (p = 0.0623), G12 -12.07%, (p = 0.0004); muscle length: CG -5.47% (p = 0.0120), G10 -3.31% (p = 0.2868), G12 0.41% (p = 0.8987); estimation of number of serial sarcomere: CG -15.42% (p = 0.0047), G10 -10.87% (p = 0.0193), G12 -4.97 (p = 0.2409); sarcomere length: CG 11.16%, (p = 0.0142), G10 9.31% (p = 0.1270), G12 5.58% (p = 0.1327). It was concluded that G12 presented the best effectiveness after immobilization period since it presented greater similarity with the non-immobilized soleus.

Remobilização por alongamento estático cíclico em músculo sóleo de ratos imobilizados em encurtamento

Muscle fibers have great plastic properties, responding to different stimuli with their weight increase or reduction, length and serial sarcomere number. The aim of this study was to analyze the static passive stretching in 3 daily bouts of 30 s and the free remobilization effects for two weeks, in the soleus muscle of rats immobilized in shortening position. For this purpose, 12 rats (Wistar) were used and divided in 2 groups: G1 (n=6) - left soleus muscle (LSM) immobilized and free in the cage (GIF); G2 (n=6) - LSM immobilized and stretched daily (GIS). The variations found between the LSM and RSM (right) of each group have been compared. The variables were: soleus muscle weight, length, serial sarcomeres number and sarcomere length. The results comparing LSM with RSM were: muscle weight: GIF=-23.16%, (p=0.0007), GIS-32.43% (p=0.0008); muscle length: GIF=-5.47% (p=0.0120); GIS=-9.99% (p=0.0034); serial sarcomere number: GIF=-15.42% (p=0.0047); GIS=-8.08% (p=0.0008); sarcomere length: GIF=11.16% (p=0.0142); GIS=-1.92% (p=0.3783). It can be concluded through these results that neither the stretching nor the free remobilization promotes restoration in the skeletal muscles structure submitted to prolonged immobilization.

Efeitos da remobilização em duas semanas com natação sobre o músculo sóleo de ratos submetidos à imobilização

Uma importante questao para a reabilitacao e como proteger o musculo esqueletico dos efeitos da imobilizacao, pois, o musculo e o mais mutavel dentre os tecidos biologicos e responde as demandas normais ou alteradas com adaptacoes morfologicas e funcionais. O objetivo deste artigo foi verificar o efeito de duas diferentes intensidades de carga de natacao sobre a morfologia do musculo soleo, e se sao eficazes para reverter o processo de atrofia causado pela imobilizacao durante o periodo de 15 dias. Foram utilizados 10 ratos, com idade de 10±2 semanas, divididos em 2 grupos: G1 (imobilizacao/natacao sem peso) e G2 (imobilizacao/natacao com sobrecarga de 10% do peso corporal). Dentro das variaveis analisadas ao comparar o membro esquerdo (submetido a imobilizacao) com o direito (nao submetido) foram observados: para peso muscular em G1=-20,55% (p=0,0344) e G2= -17,02% (p=0,0053); comprimento muscular em G1= -10,66% (p=0,0011) e G2= -6,55% (p=0,1016); estimativa de sarcomeros em serie no musculo para G1= -14,18% (p=0,0101) e G2= -10,99% (p=0,0043); e para comprimento de sarcomeros em G1= 3,51% (p=0,3989) e G2= 5,28% (p=0,1771). Conclui-se que duas semanas de remobilizacao atraves da natacao, com diferentes tipos de sobrecarga nao foram suficientes para reverter totalmente o processo de atrofia causado pela imobilizacao.

Efeito do ultra-som terapêutico contínuo em placas epifisárias de coelhos

The therapeutic efficiency of ultrasound has become an indispensable tool of physical therapy treatment in cases of alteration by lesions and in many kinds of sickness. However, in pediatric cases the use of ultrasound is controversial due to possible disturbance and damage to the growth plate. The aim of this study is to find out if the continuous ultrasound presents alteration effects on the growth plate of female rabbits. Eight New Zealand female rabbits with two months of age were tested. They were treated by continuous therapeutic ultrasound with doses of 1 W/cm2 in the lateral region of the right knee joint for five minutes, during 10 days, with an interval of two days after five applications. The left knee joint was used as a control. The histological analysis showed an alteration in the thickness of the growth plate on the treated side 24.40% bigger than in the left knee joint of the control (p < 0.0001). On other hand, the radiological analysis did not show any difference between the limbs. The conclusion was that the therapeutic ultrasound produced significant histological alterations in the cartilage thickness on the treated side according to the manner it was used in the experiment. Such fact suggests an acceleration in the growth plate metabolism.Debido a los efectos terapeuticos, la ultrasonografia se ha convertido en una herramienta indispensable al tratamiento fisioterapeutico de las alteraciones causadas por lesiones y en diversas enfermedades, a pesar de esto su uso en pacientes pediatricos es controversial por los posibles disturbios y danos a la placa epifisaria. El objetivo de este estudio es verificar si la ultrasonografia continua presenta efectos de alteracion en la placa de crecimiento de al tibia de conejas. Ocho conejas de la raza Nueva Zelanda con 2 meses de edad fueron sometidas a un tratamiento usando ultrasonografia terapeutica de forma continua con dosis de 1W/cm2 en la region lateral de la articulacion de la rodilla derecha por 5 min, durante 10 dias con 2 dias de intervalo despues de la 5a aplicacion. La articulacion de la rodilla izquierda fue utilizada como control. El analisis histologico reporto una alteracion en la espesura del cartilago epifisario, en el lado tratado el tamano fue de 24,40% mayor del que en el control (p < 0,0001); mientras que el analisis radiologico no presento ninguna diferencia entre los miembros. Por tanto, se concluye que la ultrasonografia terapeutica en la forma utilizada produce alteraciones histologicas significativas en la espesura del cartilago en el lado tratado, lo que sugiere una aceleracion en el metabolismo de la placa.

Efectos de la ultrasonografia terapéutica continua en placas epifisarias de conejos

The therapeutic efficiency of ultrasound has become an indispensable tool of physical therapy treatment in cases of alteration by lesions and in many kinds of sickness. However, in pediatric cases the use of ultrasound is controversial due to possible disturbance and damage to the growth plate. The aim of this study is to find out if the continuous ultrasound presents alteration effects on the growth plate of female rabbits. Eight New Zealand female rabbits with two months of age were tested. They were treated by continuous therapeutic ultrasound with doses of 1 W/cm2 in the lateral region of the right knee joint for five minutes, during 10 days, with an interval of two days after five applications. The left knee joint was used as a control. The histological analysis showed an alteration in the thickness of the growth plate on the treated side 24.40% bigger than in the left knee joint of the control (p < 0.0001). On other hand, the radiological analysis did not show any difference between the limbs. The conclusion was that the therapeutic ultrasound produced significant histological alterations in the cartilage thickness on the treated side according to the manner it was used in the experiment. Such fact suggests an acceleration in the growth plate metabolism.Debido a los efectos terapeuticos, la ultrasonografia se ha convertido en una herramienta indispensable al tratamiento fisioterapeutico de las alteraciones causadas por lesiones y en diversas enfermedades, a pesar de esto su uso en pacientes pediatricos es controversial por los posibles disturbios y danos a la placa epifisaria. El objetivo de este estudio es verificar si la ultrasonografia continua presenta efectos de alteracion en la placa de crecimiento de al tibia de conejas. Ocho conejas de la raza Nueva Zelanda con 2 meses de edad fueron sometidas a un tratamiento usando ultrasonografia terapeutica de forma continua con dosis de 1W/cm2 en la region lateral de la articulacion de la rodilla derecha por 5 min, durante 10 dias con 2 dias de intervalo despues de la 5a aplicacion. La articulacion de la rodilla izquierda fue utilizada como control. El analisis histologico reporto una alteracion en la espesura del cartilago epifisario, en el lado tratado el tamano fue de 24,40% mayor del que en el control (p < 0,0001); mientras que el analisis radiologico no presento ninguna diferencia entre los miembros. Por tanto, se concluye que la ultrasonografia terapeutica en la forma utilizada produce alteraciones histologicas significativas en la espesura del cartilago en el lado tratado, lo que sugiere una aceleracion en el metabolismo de la placa.

Effect of continuous therapeutic ultrasound in rabbit growth plates

The therapeutic efficiency of ultrasound has become an indispensable tool of physical therapy treatment in cases of alteration by lesions and in many kinds of sickness. However, in pediatric cases the use of ultrasound is controversial due to possible disturbance and damage to the growth plate. The aim of this study is to find out if the continuous ultrasound presents alteration effects on the growth plate of female rabbits. Eight New Zealand female rabbits with two months of age were tested. They were treated by continuous therapeutic ultrasound with doses of 1 W/cm2 in the lateral region of the right knee joint for five minutes, during 10 days, with an interval of two days after five applications. The left knee joint was used as a control. The histological analysis showed an alteration in the thickness of the growth plate on the treated side 24.40% bigger than in the left knee joint of the control (p < 0.0001). On other hand, the radiological analysis did not show any difference between the limbs. The conclusion was that the therapeutic ultrasound produced significant histological alterations in the cartilage thickness on the treated side according to the manner it was used in the experiment. Such fact suggests an acceleration in the growth plate metabolism.Debido a los efectos terapeuticos, la ultrasonografia se ha convertido en una herramienta indispensable al tratamiento fisioterapeutico de las alteraciones causadas por lesiones y en diversas enfermedades, a pesar de esto su uso en pacientes pediatricos es controversial por los posibles disturbios y danos a la placa epifisaria. El objetivo de este estudio es verificar si la ultrasonografia continua presenta efectos de alteracion en la placa de crecimiento de al tibia de conejas. Ocho conejas de la raza Nueva Zelanda con 2 meses de edad fueron sometidas a un tratamiento usando ultrasonografia terapeutica de forma continua con dosis de 1W/cm2 en la region lateral de la articulacion de la rodilla derecha por 5 min, durante 10 dias con 2 dias de intervalo despues de la 5a aplicacion. La articulacion de la rodilla izquierda fue utilizada como control. El analisis histologico reporto una alteracion en la espesura del cartilago epifisario, en el lado tratado el tamano fue de 24,40% mayor del que en el control (p < 0,0001); mientras que el analisis radiologico no presento ninguna diferencia entre los miembros. Por tanto, se concluye que la ultrasonografia terapeutica en la forma utilizada produce alteraciones histologicas significativas en la espesura del cartilago en el lado tratado, lo que sugiere una aceleracion en el metabolismo de la placa.