Edward C. Geehr

Bacteriology of the marine environment: Implications for clinical therapy

Ocean water and tissue samples were obtained from a variety of sources with phylogenetic and geographic diversity. Purified bacterial colonies were isolated and identification procedures were performed. A total of 67 isolates were recovered. Thirty-eight isolates belonged to the genus Vibrio and included six species. Twenty-four non-fermentative bacteria and four Gram-positive isolates were recovered. Antibiotic susceptibility testing showed that while the non-fermentative marine bacteria generally were susceptible to the antibiotics tested, marine Vibrio species were relatively resistant to a wide variety of antimicrobials. Antibiotics effective against all species included imipenem, trimethoprim/sulfamethoxazole, and chloramphenicol. Further recommendations for treatment are based on sensitivity in culture. Some isolates failed to grow in the medium used for susceptibility testing. Because commercial test kits may not yield accurate identifications of bacteria, the acquisition of antimicrobial susceptibility data gains added importance.

Efficacy of gastric emptying: Gastric lavage versus emesis induced with ipecac

A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% +/- 34% compared with 50% +/- 35%). There was a significant difference between the two groups (P less than .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.

Emergency health impact of a severe storm.

A severe, premature snow storm resulted in widespread loss of power, communications, and transportation in a populous region of the Northeast. Staff in hospital emergency departments centered in the path of the storm reported a large number of injuries and many unexpected health effects related to the storm. A retrospective survey of the five major hospital emergency departments serving the most heavily affected urban and suburban areas was undertaken to determine the emergency health impact of the storm and resulting operational problems. Expected findings included a decrease in emergency department visits the day of the storm, followed by a sharp increase the day after. Clean-up activities accounted for a large number of the injuries, most of which were preventable. Unexpected findings include a large number of carbon monoxide poisonings and disposition and staffing problems created by caring for many patients who lost access to customary home health care services. Emergency department staff are encouraged to engage in public education efforts that may reduce serious illness or injury related to severe weather and its aftermath. Moreover, traditional disaster plans may need to be supplemented in anticipation of the disposition and staffing problems created by a growing population of elderly patients who will be cut off from vital home health care services by severe weather.

Analyzing clinical case distributions to improve an emergency medicine clerkship

Recommendations for a core curriculum for undergraduate emergency medicine education have been published. It is expected that a combination of bedside teaching and didactic sessions will cover all aspects of the curriculum, but this has not been demonstrated. This study describes a method of using the distribution of clinical cases to shape the mix of clinical and didactic learning in an emergency medicine clerkship. All senior students at the Albany Medical College participate in a four-week emergency medicine rotation. A brief log describing each clinical encounter is maintained by the students. Data from one year were sorted into 32 categories adapted from American College of Emergency Physicians guidelines and were tabulated. A criterion of 80% of students encountering at least one case in each category was chosen to ensure a reasonable level of exposure to a particular case or topic. One hundred twenty-three students were exposed to an average of 63.7 +/- 27.5 (SD) patients. Seven categories met the criterion, and the remaining 25 categories failed the criterion. Results indicate that exposure to certain categories of patients with appropriate monitoring can be reasonably ensured in our clinical setting. The didactic portion of the curriculum can be adjusted so that categories not meeting the clinical criterion will be emphasized, whereas those meeting the criterion will be de-emphasized. A method has been described that identifies gaps in the clinical exposure of students and permits appropriate identification of didactic sessions to create a clerkship more consistent with recommended guidelines.

Effect of pneumatic trousers on pulmonary function.

Little information is available concerning the effect of pneumatic antishock trousers (PT) on pulmonary function. To examine this issue, we measured the effects of PT inflation on forced expired volumes, subdivisions of lung volume, quasistatic lung compliance, single-breath diffusing capacity for carbon monoxide, and transdiaphragmatic pressure at resting lung volume in 10 healthy nonsmoking adults. All subjects were studied seated without PT, supine with PT uninflated, and supine with PT inflated to 100 mm Hg. When seated subjects assumed the supine position without PT inflation, significant reductions were found in the forced expired volume in 1 sec, in subdivisions of lung volume, total lung capacity (TLC), functional residual capacity (FRC), expiratory reserve volume (ERV) and in transdiaphragmatic pressure. However, PT inflation itself did not produce significant changes in any of the measured pulmonary indices except transdiaphragmatic pressure. We conclude that PT inflation in supine normovolemic individuals does not produce acutely significant alterations in lung function.

Transcutaneous oxymetry measurements during acute blood loss.

Transcutaneous PO2 (TcPO2) was measured in healthy adult blood donors to test the sensitivity of this method as a noninvasive means of diagnosing occult blood loss. TcPO2, the energy required to heat the electrode (MW), and postural changes in blood pressure and pulse, were measured before and after a 450-ml blood donation. There was a significant increase (P less than .005) in postural pulse of 4.8/min, but no significant change (P greater than .05) in postural blood pressure. There was no significant change (P greater than .05) in TcPO2, but there was a significant decrease (P less than .001) in MW. These MW changes probably reflect physiologic changes associated with blood loss.