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Dive into the research topics where Edward J. Driscoll is active.

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Featured researches published by Edward J. Driscoll.


Oral Surgery, Oral Medicine, Oral Pathology | 1963

L form of bacteria isolated from recurrent aphthous stomatitis lesions

Michael F. Barile; Edward A. Graykowski; Edward J. Driscoll; Donald B. Riggs

Abstract Pure cultures of a transitional L form isolated from numerous lesions in three aphthous stomatitis patients examined suggest that a relationship exists between the L form of bacteria and the pathogenesis of this disease and that some cases of recurrent aphthous stomatitis may be infectious in nature. The “L form theory” presented proposes that the stable L form variant of pathogenic bacteria is the dormant-carrier agent in recurrent aphthous ulcerations.


Oral Surgery, Oral Medicine, Oral Pathology | 1958

Oral manifestations of leukemia.

John H. Duffy; Edward J. Driscoll

Abstract We have presented a description of the effects of leukemia and the antileukemia drugs on the oral tissues. There are set forth suggestions for dental prophylactic and therapeutic care of leukemia patients, based on clinical and histopathologic findings.


Anesthesia & Analgesia | 1980

Recovery following intravenous sedation during dental surgery performed under local anesthesia.

Stephen S. Gelfman; Richard H. Gracely; Edward J. Driscoll; Donald P. Butler; James B. Sweet; Peggy R. Wirdzek

Recovery of psychomotor and perceptual performance from two combinations of intravenous sedatives was assessed in 124 oral surgical patients undergoing third molar extractions under local infiltration anesthesia. Ninety-four patients in the experimental group received 15 mg of diazepam and 20 to 200 mg of methohexital intravenously on one occasion and 12.5 mg of diazepam, 20 to 200 mg of methohexital, and 0.1 mg of fentanyl intravenously on another occasion in a randomized, crossover design. Thirty patients in the control group received saline placebo intravenously during a single surgery. Both drug combinations produced significantly prolonged decrements in performance in comparison to placebo. Reduction in the diazepam dose from 15 to 12.5 mg and the addition of fentanyl, a short-acting narcotic, produced greater sedation without prolonging recovery. Psychomotor function recovered to preoperative levels before perceptual performance. These results show that postsurgical deficits in psychomotor and perceptual function result from the sedative drugs and not from the effects of local anesthetics or physiologic and psychological responses to surgery. These results also suggest that psychomotor tests are inappropriate measures of recovery and that superior sedation with rapid recovery may be achieved with reduced doses of longer acting agents such as diazepam and with the addition of shorter acting agents that do not prolong recovery.


Journal of Oral and Maxillofacial Surgery | 1983

Evaluation by thoracic impedance cardiography of diazepam, placebo, and two drug combinations for intravenous sedation of dental outpatients

Raymond A. Dionne; Edward J. Driscoll; Donald P. Butler; Peggy R. Wirdzek; James P. Sweet

The cardiovascular and respiratory effects of three common intravenous premedicants were examined noninvasively in a population of 20 dental outpatients scheduled for surgical removal of third-molars. Two third molars from one side of the mouth were removed at each appointment. Group 1 received a diazepam titration (mean dose = 25.6 mgs) at one appointment and placebo at the other appointment. Group 2 received a combination of diazepam (12.5 mg), fentanyl (0.1 mg), and methohexital (mean dose = 18.0 mg) at one appointment and the combination of diazepam (15.0 mg) and methohexital (mean dose = 27.0 mg) at the other appointment. Noninvasive measurement of cardiac output revealed little change during intravenous drug administration, but a significant increase was seen in all groups following local anesthesia and during surgery. Heart rate was elevated and stroke volume decreased during administration of the two-drug combinations. Oxygen saturation was greatly decreased following the combination of diazepam, fentanyl, and methohexital. These findings indicate that the combination of diazepam, fentanyl, and methohexital results in decreased oxygen saturation, a transient decrease in stroke volume, and an elevated heart rate when used as an intravenous premedicant for dental outpatients.


Journal of the American Dental Association | 1980

Occupational Disease in Dentistry and Chronic Exposure to Trace Anesthetic Gases

Ellis N. Cohen; Byron W. Brown; Marion L. Wu; Charles Whitcher; Jay B. Brodsky; Helen C. Gift; William Greenfield; Thomas W. Jones; Edward J. Driscoll


Journal of the American Dental Association | 1960

Blood sampling and cultural studies in the detection of postoperative bacteremias

Morrison Rogosa; Edward G. Hampp; Thomas A. Nevin; Henry N. Wagner; Edward J. Driscoll; Paul N. Baer


Journal of oral surgery | 1981

Cardiovascular and respiratory response to intravenous diazepam, fentanyl, and methohexital in dental outpatients.

Raymond A. Dionne; Edward J. Driscoll; S. S. Gelfman; James B. Sweet; Donald P. Butler; Peggy R. Wirdzek


Oral Surgery, Oral Medicine, Oral Pathology | 1961

True (attached) cementoma with root canal involvement. Report of a case.

F.W. Wertheimer; Edward J. Driscoll; Harold R. Stanley


Journal of oral surgery | 1979

Comparison of recovery tests after intravenous sedation with diazepam-methohexital and diazepam-methohexital and fentanyl

S. S. Gelfman; Richard H. Gracely; Edward J. Driscoll; Peggy R. Wirdzek; Donald P. Butler; James B. Sweet


Journal of oral surgery | 1979

Thrombophlebitis after intravenous use of anesthesia and sedation: its incidence and natural history.

Edward J. Driscoll; S. S. Gelfman; James B. Sweet; Donald P. Butler; Wirdzck Pr; Medlin T

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Donald P. Butler

National Institutes of Health

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James B. Sweet

National Institutes of Health

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Peggy R. Wirdzek

National Institutes of Health

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S. S. Gelfman

National Institutes of Health

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Richard H. Gracely

National Institutes of Health

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Raymond A. Dionne

National Institutes of Health

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Carl L. White

National Institutes of Health

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