Edward P. Buchanan

History of synthetic materials in alloplastic cranioplasty

When faced with calvarial defects, surgeons have long searched for repair materials. General criteria include ease of use, low cost, availability, cosmetic shape, and osteointegrative potential. While autologous bone is widely used and favored in contemporary reconstructive procedures, synthetic alternatives have been used throughout history and are necessary in current practice for select cases when autograft reconstruction is not an option (such as cases with severe bony comminution, bone graft resorption, infection, and limited donor site options). For centuries, surgeons have experimented with metals, ceramics, plastics, and later, resorbable polymers. This paper provides a tour of the materials that have been used and experimented with throughout the history of alloplastic cranioplasty.

LeFort I Osteotomy

The LeFort I osteotomy is one of the most commonly used procedures to correct midface deformities. It allows for correction in three dimensions including advancement, retrusion, elongation, and shortening. It is indicated, often in conjunction with mandibular surgery, for class II and III malocclusion, facial asymmetry, obstructive sleep apnea, and maxillary atrophy. Before surgery, proper orthodontics and surgical planning should be undertaken to ensure adequate outcomes. Overall, the surgery is widely used due to its low complication profile and reliable long-term results.

Prenatal Identification of Pierre Robin Sequence: A Review of the Literature and Look towards the Future

Fetal ultrasonography is an important tool used to prenatally diagnose many craniofacial conditions. Pierre Robin sequence (PRS) is a rare congenital deformation characterized by micrognathia, glossoptosis, and airway obstruction. PRS can present as a perinatal emergency when the retropositioned tongue obstructs the airway leading to respiratory compromise. More predictable and reliable diagnostic studies could help the treating medical team as well as families prepare for these early airway emergencies. The medical literature was reviewed for different techniques used to prenatally diagnose PRS radiologically. We have reviewed these techniques and suggested a possible diagnostic pathway to consistently identify patients with PRS prenatally.

Cleft Nasal Deformity and Rhinoplasty

The cleft nasal deformity is a complex challenge in plastic surgery involving the skin, cartilage, mucosa, and skeletal platform. Ever since Blair and Brown first described the intricacies of the cleft pathology in 1931, the appropriate approach has been extensively debated in the literature with respect to timing, technique, and extent of surgical intervention. In this article, the authors review the literature and summarize the various modalities for achieving a successful rhinoplasty in the patient with a cleft nasal deformity.

A Novel Quantitative Method for Evaluating Surgical Outcomes in Craniosynostosis: Pilot Analysis for Metopic Synostosis

Objective assessment of head shape has been an elusive goal in the management of craniosynostosis patients. Clinical judgment, craniometric indices, and computed tomography scans are the primary means through which a surgeon assesses this patient population. The purpose of this study was to examine and discuss the utility of the STARscanner for evaluation of surgical outcomes in metopic synostosis patients. A retrospective chart review of patients with metopic synostosis who underwent fronto-orbital advancement with pre- and postoperative STARscanner imaging at Texas Childrens Hospital was performed. Two patients were identified and evaluation and discussion of the data produced by the STARscanner was undertaken. A novel symmetry index created by the authors, called the anterior–posterior volume ratio (APVR), was discussed for use in metopic synostosis patients. The postoperative growth metrics demonstrated an interval increase compared with the preoperative data. The anterior symmetry ratio, posterior symmetry ratio, overall symmetry ratio, cranial vault volumes, cranial vault asymmetry index, and cephalic ratio were not found to be useful in evaluating resolution of dysmorphology after fronto-orbital advancement in metopic synostosis. The APVR does not characterize dysmorphology, but may help show degree of expansion of the anterior cranial vault after fronto-orbital advancement. The STARscanner imaging device does not appear to have significant utility in characterizing head shape for surgical outcomes assessment in metopic synostosis. The minor utility of this device may be that it is a safe and fast way to derive growth parameters for both short-term and long-term follow-up of cranial vault remodeling.

Late presenting nasal deformities after nasal continuous positive airway pressure injury: 33-year experience

PURPOSE This study was designed to characterize the resultant nasal deformities seen in adolescent and adult patients who sustained nasal continuous positive airway pressure (nCPAP) injuries during their NICU admission. PATIENTS AND METHODS Data from patients who sustained nCPAP injury in the NICU and seen for plastic surgery evaluation at one institution over the past 33 years was collected. Exclusion criteria were patients with additional nasal trauma after nCPAP injury. A retrospective review was performed, including demographics, time of initial injury, surgical timing, associated medical history, nasal function and photographs. Deformities were characterized according to aesthetic nasal subunit location and secondary nasal deformities. Outcome measures included the need and type of surgical correction, presence of airway obstruction, and surgical complications. RESULTS 11 patients were included; the average age was 13.9±4.6 years. The average gestational age was 26.5±1.6 weeks. All of the nasal deformities included the inferior third of nose. The nasal soft triangle and columella were the most common subunits affected. Three patients had combined deformities with involvement of at least two nasal subunits. All injuries resulted in secondary nasal deformities, including nostril asymmetry, columellar asymmetry, nasal tip deviation, lack of projection and nasal airway obstruction. All patients required at least two operative interventions for treatment. Mean age of initial reconstruction was 7.2 years. Despite surgical intervention, secondary deformities and nasal airway obstruction was still present. CONCLUSION Late presenting nCPAP injury deformities most commonly affect the lower third of the nose and can result in a myriad of secondary nasal deformities. The nasal soft triangle and columella were the most commonly involved subunits. Secondary deformities involved the nasal aesthetic subunits adjacent to the primarily affected areas, resulting in asymmetry as well as nasal airway obstruction. Most patients required staged open nasal reconstruction with composite grafts.

Treatment effects of dexmedetomidine and ketamine on postoperative analgesia after cleft palate repair.

Primary cleft palate repair may result in significant pain in the immediate postoperative period, which can lead to vigorous crying resulting in wound dehiscence and pulmonary complications. Effective pain control with opioids is the mainstay but administration on the floor has to be countered with the complications associated with their use, chiefly respiratory depression and sedation. We retrospectively examined the efficacies of intraoperative administration of intravenous (IV) dexmedetomidine (DEX) and ketamine (KET) to prevent early postoperative pain in children undergoing primary cleft palate repair and compared the results against relevant literature. The Texas Childrens Hospital anesthesia database was queried to identify children undergoing a palatal surgery from December 2011 to December 2012. Inclusion criteria permitted completed primary palatal surgery without major complications and intraoperative administration of DEX or KET. The control group (CTRL) received no additional drug. A comprehensive literature review was performed. A total of 71 pediatric patients underwent palatal surgery during the study period with 46 patients qualifying for analysis. Although results were not significant, consistent trends were observed with regards to lower opioid requirements during the first 24 hours for both medications compared with the CTRL. KET also had shorter time to discharge. The literature review resulted in several studies supporting decreased postoperative pain end points for both DEX and KET. In our sample, DEX and KET reduced postoperative opioid requirements. KET seems to have the added benefit of a shorter hospital stay. These finding are supported in the literature. With further investigation, the addition of these drugs may serve to provide improved pain relief without over sedation in patients undergoing cleft palate repair.

Virtual surgical planning and 3D printing in repeat calvarial vault reconstruction for craniosynostosis: technical note

Repeat surgery for restenosis after initial nonsyndromic craniosynostosis intervention is sometimes needed. Calvarial vault reconstruction through a healed surgical bed adds a level of intraoperative complexity and may benefit from preoperative and intraoperative definitions of biometric and aesthetic norms. Computer-assisted design and manufacturing using 3D imaging allows the precise formulation of operative plans in anticipation of surgical intervention. 3D printing turns virtual plans into anatomical replicas, templates, or customized implants by using a variety of materials. The authors present a technical note illustrating the use of this technology: a repeat calvarial vault reconstruction that was planned and executed using computer-assisted design and 3D printed intraoperative guides.

Posterior cranial vault distraction in the treatment of shunt-induced craniosynostosis.

Cerebrospinal fluid shunt placement is the most common surgical intervention for hydrocephalus. In rare cases, cerebrospinal fluid shunting has been associated with the development of secondary craniosynostosis. Posterior cranial vault distraction osteogenesis is an emerging technique used for the treatment of craniosynostosis. Posterior vault distraction allows greater intracranial volume expansion than do techniques that address the anterior cranium. We present a patient with shunt-induced multisuture craniosynostosis with delayed presentation. She was effectively treated with posterior cranial vault distraction and preservation of her ventriculoperitoneal shunt. This unique case demonstrates the safety and utility of this procedure for complex craniocerebral disproportion.

Secondary Lip and Palate Surgery

To properly treat a patient with a secondary cleft lip or palate deformity, one must make an accurate diagnosis of the underlying problem. Recognition of specific recurring patterns and common deformities will help facilitate the surgical planning process and assist the surgeon during future procedures. Through a combination of accurate analysis, clinical patience, and technical precision, successful correction of secondary cleft lip and palate deformities can be delivered.