Efraim Shek | Researchain

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Featured researches published by Efraim Shek.

Synthetic Communications | 1987

Facile, One-Step Preparation of Trigonellinate Esters

Marcus E. Brewster; Vasudevan Venkatraghavan; Efraim Shek; Nicholas Bodor

Abstract Trigonelline anhydride was synthesized and was found to readily react with various alcohols to yield the corresponding trigonellinate esters.

Journal of Medicinal Chemistry | 1986

Sustained brain-specific delivery of estradiol causes long-term suppression of luteinizing hormone secretion.

James W. Simpkins; Jill McCornack; Kerry S. Estes; Marcus E. Brewster; Efraim Shek; Nicholas Bodor

Journal of Medicinal Chemistry | 1989

Improved delivery through biological membranes. 38. Brain-specific chemical delivery systems for .beta.-lactam antibiotics. Synthesis and properties of some dihydropyridine and dihydroisoquinoline derivatives of benzylpenicillin

Emil Pop; Whei Mei Wu; Efraim Shek; Nicholas Bodor

Journal of Pharmaceutical Sciences | 1989

Improved Anticonvulsant Activity of Phenytoin by a Redox Brain Delivery System III: Brain Uptake and Pharmacological Effects

Efraim Shek; Teruo Murakami; Chandishwar Nath; Emil Pop; Nicholas Bodor

Journal of Medicinal Chemistry | 1989

Brain-specific chemical delivery systems for beta-lactam antibiotics. Synthesis and properties of some dihydropyridine and dihydroiosquinoline derivatives of benzylpenicillin.

Emil Pop; Wu Wm; Efraim Shek; Nicolae S. Bodor

Journal of Pharmaceutical Sciences | 1989

Improved Anticonvulsant Activity of Phenytoin by a Redox Brain Delivery System I: Synthesis and Some Properties of the Dihydropyridine Derivatives

Emil Pop; Efraim Shek; Teruo Murakami; Nicholas Bodor

Journal of Medicinal Chemistry | 1989

Improved delivery through biological membranes. 39. Brain-specific chemical delivery systems for .beta.-lactam antibiotics. In vitro and in vivo studies of some dihydropyridine and dihydroisoquinoline derivatives of benzylpenicillin in rats

Whei Mei Wu; Emil Pop; Efraim Shek; Nicholas Bodor

Journal of Medicinal Chemistry | 1989

Brain-specific chemical delivery systems for beta-lactam antibiotics. In vitro and in vivo studies of some dihydropyridine and dihydroisoquinoline derivatives of benzylpenicillin in rats.

Wu Wm; Emil Pop; Efraim Shek; Nicolae S. Bodor

Journal of Pharmaceutical Sciences | 1989

Improved Anticonvulsant Activity of Phenytoin by a Redox Brain Delivery System II: Stability in Buffers and Biological Materials

Teruo Murakami; Efraim Shek; Emil Pop; Nicholas Bodor

Journal of Medicinal Chemistry | 1989

Brain-specific chemical delivery systems for β-lactam antibiotics: synthesis and properties of some dihydropyridine and dihydroisoquinoline derivatives of benzylpenicillin

Emil Pop; Wu Wm; Efraim Shek; Nicolae S. Bodor

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University of Florida

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University of Florida

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Nicolae S. Bodor

University of Florida

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University of Florida

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University of Florida

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Marcus E. Brewster

University of Florida

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Chandishwar Nath

University of Florida

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James W. Simpkins

University of Florida

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University of Florida

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University of Florida

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