Eiki Okuda | Researchain

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Featured researches published by Eiki Okuda.

Jpn J Gastroenterol Surg, Nihon Shokaki Geka Gakkai zasshi | 2001

The Therapeutic Strategy of Submucosal Esophageal Cancer by Clinicophathological Findings and Lymph Node Metastasis.

Masashi Takemura; Harushi Osugi; Nobuyasu Takada; Satoru Kishida; Masahiro Nishikawa; Eiki Okuda; Masakatsu Ueno; Yoshinori Tanaka; Kennichirou Fukuhara; Hiroaki Kinoshita

食道粘膜下層癌の治療方針を臨床病理学的因子・リンパ節転移の状況より検討した.対象と方法:3領域リンパ節郭清術を施行した症例のうち主病巣の病理組織学的検索でpT1bであった50例を用いた.結果:リンパ節転移は18例にみられ, 転移陰性32例に高分化型扁平上皮癌, 脈管侵襲陰性例が多かった. 多変量解析では脈管侵襲の有無がリンパ節転移に最も関与した因子であった. 総郭清リンパ節2532個中63個に転移を認め, 長径10mm以下は41個・6mm以下は19個であった. 9mm以下のリンパ節で, 肉眼的転移判定は困難であった. リンパ節再発が2例, 血行性転移が3例にみられ, 5年生存率は84%で, 脈管侵襲陽性例の生存率が有意に悪かった.結語:粘膜切除可能なpT1b 食道癌には診断的粘膜切除を行い, 高分化型扁平上皮癌で脈管侵襲陰性の場合はリンパ節転移の可能性が低いが, これ以外の症例には追加治療としてリンパ節郭清が必要である.

Clinical Cancer Research | 2001

Detection of p53 Gene Mutations in Human Esophageal Squamous Cell Carcinomas Using a p53 Yeast Functional Assay: Possible Difference in Esophageal Carcinogenesis Between the Young and the Elderly Group

Eiki Okuda; Harushi Osugi; Keiichirou Morimura; Nobuyasu Takada; Masashi Takemura; Shoji Fukushima; Masayuki Higashino; Hiroaki Kinoshita

International Journal of Oncology | 2002

p53 null mutations detected by a p53 yeast functional assay predict a poor outcome in young esophageal carcinoma patients

Harushi Osugi; Keiichirou Morimura; Eiki Okuda; Masashi Takemura; Masayuki Higashino; Nobuyasu Takada; Hiroaki Kinoshita

Jpn J Gastroenterol Surg, Nihon Shokaki Geka Gakkai zasshi | 1999

A Case of Cancer in the Stomach Used for Posterior Mediastinal Reconstruction after Radical Operation for Esophageal Cancer.

Kenichiro Fukuhara; Harushi Osugi; Nobuyasu Takada; Yoshihiko Nishimura; Takanobu Funai; Shigeru Ree; Shinichi Taguchi; Miyuki Fujita; Eiki Okuda; Hiroaki Kinoshita

Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 2001

TWO CASES OF RESECTED UNDIFFERENTIATED CARCINOMA OF THE CERVICAL ESOPHAGUS

Eiki Okuda; Harushi Osugi; Nobuyasu Takada; Masashi Takemura; Masahiro Kaneko; Hiroaki Kinoshita

Hepato-gastroenterology | 2004

The prognostic factors after radical esophagectomy for esophageal cancer with positive preoperative CEA.

Masashi Takemura; Harushi Osugi; Nobuyasu Takada; Eiki Okuda; Masakatsu Ueno; Hiroaki Kinoshita

Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 2001

THREE CASES OF RESECTED SO-CALLED CARCINOSARCOMA OF THE ESOPHAGUS AND REVIEW OF THE JAPANESE LITERATURE

Masashi Takemura; Harushi Osugi; Nobuyasu Takada; Eiki Okuda; Masakatsu Ueno; Hiroaki Kinoshita

Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 1999

CLINICAL SIGNIFICANCE OF METASTASIS TO CERVICAL NODES IN PATIENTS WITH INTRATHORACIC ESOPHAGEAL CANCER WHO HAD EXTENDED LYMPHADENECTOMY

Harushi Osugi; Masayuki Higashino; Taigou Tokuhara; Nobuyasu Takada; Yoshihiko Nishimura; Masashi Takemura; Takanobu Funai; Shigeru Le; Miyuki Fujita; Shinichi Taguchi; Eiki Okuda; Hiroaki Kinoshita

Jpn J Gastroenterol Surg, Nihon Shokaki Geka Gakkai zasshi | 1999

Significance of Ambulatory Intraesophageal Bilirubin Monitoring in Diagnosis of Gastroesophageal Reflux.

Harushi Osugi; Masayuki Higashino; Taigou Tokuhara; Susumu Kaseno; Nobuyasu Takada; Yoshihiko Nishimura; Masasi Takemura; Takanobu Funai; Eiki Okuda; Hiroaki Kinoshita

Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 2000