El-Said Abdel-Hady

Outcome of the use of tension-free vaginal tape in women with mixed urinary incontinence, previous failed surgery, or low valsalva pressure.

Aim: To assess the safety and efficacy of the use of tension‐free vaginal tape (TVT) for the treatment of stress urinary incontinence (SUI) in women with mixed incontinence, previous failed incontinence surgery or low valsalva leak point pressure (VLPP).

Midtrimester abortion using vaginal misoprostol for women with three or more prior cesarean deliveries

To evaluate the safety and efficacy of vaginal misoprostol for second‐trimester abortion in women with 3 or more prior cesarean deliveries.

Hematological profile and transfusion requirement during hysteroscopic myomectomy: A comparative study between oxytocin and tranexamic acid infusion

Abstract Background Oxytocin is uterotonic drug reducing uterine blood loss. Tranexamic acid reduce blood loss in various settings. Data on their efficacy are limited in gynecological hysteroscopy. This study was conducted to compare the effect of oxytocin versus tranexamic acid on hematological profile and transfusion requirement during hysteroscopic myomectomy (HM). Methods Fifty women scheduled for HM were randomly assigned into two groups. Ttranexamic acid (TXA) or oxytocin (OXY). TXA was injected with 15 mg kg−1 of tranexamic acid, followed by infusion of 10 mg kg−1 h−1. In OXY, 10 Unites of oxytocin were added to 500 mL saline (400 mU/min) during surgery. Spinal anesthesia was induced for all patients. Hemodynamics, hematological data, number of transfusions, serum sodium and central venous pressure were measured. Results TXA showed significant decrease of heart rate 30 and 45 min and 1 and 2 h when compared with OXY. Post operative Hb and Hct showed significant decrease (p < 0.001) in TXA compared with OXY. CVP in TXA displayed significant increase (p < 0.001) 15 min after spinal blockade and 30 min, 45 min, 1 h and 2 h. Serum sodium showed significant decrease in TXA (p < 0.001) compared with OXY nearly throughout study period. Conclusion Use of oxytocin during HM was accompanied with stable hemodynamics, hematological profile and less transfusion requirement compared with the use of tranexamic acid.

Can Revised Visual Inspection with Acetic Acid (VIA) Test Improve the Performance of Crude VIA Test of in Low-Resource-Setting Countries?

PurposeTo compare the performance of our suggested “revised VIA” test to the traditional crude VIA test.MethodsA cross-sectional study was conducted in the early cancer detection unit. During the period from June 2014 to January 2016, 500 patients were included in our study. After clinical assessment, VIA test was performed followed by applying the five criteria of the revised test at the same time. All cases were referred to colposcopy for confirmation. Cervical punch biopsy was performed for cases with positive colposcopic findings.ResultsThe prevalence of CIN in this study was 11/500 (2.2%). The positive cases with crude VIA test were 236 of 500 screened women (47%). Its sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy (100, 53.98, 4.66, 100, and 55%, respectively). When we applied the five criteria of our suggested “revised VIA” test, only 175 cases (35%) were positive. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy became 100, 66.46, 6.28, 100, and 67%, respectively.ConclusionThe suggested “revised VIA” test improved the performance of the crude VIA test by improving its specificity. We recommend further studies to evaluate its performance.