Elena Vera-Iglesias

Hiperplasia epitelial focal

Focal epithelial hyperplasia is a rare disease of the oral mucosa caused by the human papilloma virus (HPV). It appears as a benign epithelial growth, usually in the mucosa of the lower lip. It is mainly associated with HPV serotypes 13 and 32 and there is a clear racial predilection for the disease in Native Americans and Eskimos. We describe the case of a 17-year-old girl from Ecuador with multiple papular lesions in both lips that were clinically and histologically consistent with focal epithelial hyperplasia. Analysis by polymerase chain reaction detected HPV serotype 13.

Focal epithelial hyperplasia

Focal epithelial hyperplasia is a rare disease of the oral mucosa caused by the human papilloma virus (HPV). It appears as a benign epithelial growth, usually in the mucosa of the lower lip. It is mainly associated with HPV serotypes 13 and 32 and there is a clear racial predilection for the disease in Native Americans and Eskimos. We describe the case of a 17-year-old girl from Ecuador with multiple papular lesions in both lips that were clinically and histologically consistent with focal epithelial hyperplasia. Analysis by polymerase chain reaction detected HPV serotype 13.

Multiple Vulvar Papules

A 46-year-old woman with no personal or family history of interest consulted for asymptomatic vulvar lesions that appeared 4 months earlier. She had not undergone any treatment. Both labia majora had multiple whitish, monomorphous papules of cystic appearance and with a diameter of 3 mm (Figure 1). No lesions were observed in the rest of the vulva. A biopsy was taken of one of the lesions (Figure 2). Histopathology A histopathological study of one of the lesions showed that the dermis contained a cystic cavity lined by a stratified squamous epithelium with a granular layer (Figure 2).

Lesiones ampollosas en las manos

Varon de 75 anos con antecedentes de hipertension arterial en tratamiento con indapamida y valsartan desde hace anos, e ingresado en el servicio de digestivo por una pancreatitis aguda grave, por lo que se anade a su tratamiento habitual terapia intravenosa con paracetamol, metilprednisolona, pantoprazol e imipenem y fraxiparina subcutanea. A los 3 dias del ingreso se anade captopril oral debido a que la presion no se controla. Durante las 2 semanas siguientes, el paciente va mejorando lentamente de su pancreatitis, pero refiere la aparicion de lesiones ampollosas asintomaticas en las manos de 3 dias de evolucion. Exploracion fisica En los laterales de ambas munecas, las manos y los dedos se observan sobre piel normal lesiones vesiculoampollosas de contenido seroso que siguen una disposicion lineal (fig. 1). En ambas palmas presenta lesiones poco llamativas, eritematoedematosas pero con tendencia a formar dianas. No se observan lesiones en las mucosas. Se realiza biopsia para estudio con hematoxilina e IFD, e IFI.