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Elie A. Tabet

University of North Carolina at Chapel Hill

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Featured researches published by Elie A. Tabet.

Journal of Organic Chemistry | 2011

An enyne cycloisomerization approach to the triple reuptake inhibitor GSK1360707F.

Nicole M. Deschamps; Vassil I. Elitzin; Bing Liu; Mark B. Mitchell; Matthew J. Sharp; Elie A. Tabet

The triple reuptake inhibitor GSK1360707F was synthesized via an efficient and scalable route that features an enyne cycloisomerization reaction catalyzed by either Pt(II) or Au(I). Key aspects of this work such as the choice of the nitrogen protecting group and initial enantioselectivity studies are discussed.

Journal of Organic Chemistry | 2001

Asymmetric aldol additions: use of titanium tetrachloride and (-)-sparteine for the soft enolization of N-acyl oxazolidinones, oxazolidinethiones, and thiazolidinethiones.

Michael T. Crimmins; Bryan W. King; Elie A. Tabet; Kleem Chaudhary

Journal of the American Chemical Society | 1997

ASYMMETRIC ALDOL ADDITIONS WITH TITANIUM ENOLATES OF ACYLOXAZOLIDINETHIONES : DEPENDENCE OF SELECTIVITY ON AMINE BASE AND LEWIS ACID STOICHIOMETRY

Michael T. Crimmins; Bryan W. King; Elie A. Tabet

Journal of the American Chemical Society | 2000

Total Synthesis of (+)-Prelaureatin and (+)-Laurallene

Michael T. Crimmins; Elie A. Tabet

Journal of Organic Chemistry | 2001

Formal total synthesis of (+)-trehazolin. Application of an asymmetric aldol-olefin metathesis approach to the synthesis of functionalized cyclopentenes.

Michael T. Crimmins; Elie A. Tabet

Organic Letters | 2001

An aldol approach to the synthesis of the EF fragment of spongistatin 1

Michael T. Crimmins; Jason D. Katz; Laura C. McAtee; Elie A. Tabet; Steven J. Kirincich

Organic Letters | 2003

Toward a structure-activity relationship for apoptolidin: selective functionalization of the hydroxyl group array.

Paul A. Wender; Orion D. Jankowski; Elie A. Tabet; Haruo Seto

Organic Letters | 2003

Facile synthetic access to and biological evaluation of the macrocyclic core of apoptolidin.

Paul A. Wender; Orion D. Jankowski; Elie A. Tabet; Haruo Seto

Organic Letters | 2006

Correlation of F0F1-ATPase inhibition and antiproliferative activity of apoptolidin analogues.

Paul A. Wender; Orion D. Jankowski; Kate E. Longcore; Elie A. Tabet; Haruo Seto; Taijiro Tomikawa

Organic Process Research & Development | 2016

Development of Large-Scale Routes to Potent GPR119 Receptor Agonists

Richard T. Matsuoka; Eric E. Boros; Andrew D. Brown; Kae M. Bullock; Will L. Canoy; Andrew J. Carpenter; Jeremy D. Cobb; Shannon E. Condon; Nicole M. Deschamps; Vassil I. Elitzin; Greg Erickson; Jing M. Fang; David H. Igo; Biren K. Joshi; Istvan Kaldor; Mark B. Mitchell; Gregory Peckham; Daniel W. Reynolds; Matthew C. Salmon; Matthew J. Sharp; Elie A. Tabet; Jennifer F. Toczko; Lianming Michael Wu; Xiao-ming M. Zhou

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