Élio Vieira

Angiomatoid fibrous histiocytoma of the arm treated by radiotherapy for local recurrence—Case report

The Angiomatoid Fibrous Histiocytoma is a rare tumor of soft tissues, which occurs mainly in children and young adults, with low malignancy grade. It has the capacity of local recurrence, but rarely metastizes. It is frequently difficult to differentiate this from vascular tumors, namely hemangioendotheliomas and angiosarcomas, or simply organized hematomas. The authors present a case of a patient with an angiomatoid fibrous histiocytoma of the arm, treated with radiotherapy after three postsurgical recurrences.

Hemangioendothelioma: A Rare Vascular Tumor in Childhood and Adolescence

Most vascular tumors occurring in children are benign. They are recognized by their ability to form angiomatous structures. In some instances, there is no clear-cut line between a benign vascular tumor (or angioma) and a malignant vascular tumor (or angiosarcoma). The hemangioendothelioma is a rare tumor of vascular origin, involving bone or soft tissue, and represents 1% of all vascular neoplasms. Accurate diagnosis is critical in recommending the most appropriate therapy for each patient. The aim of this paper is to give a brief review of the literature of this rare entity, particularly in childhood and adolescence.

208 G2 block in irradiated cervix tumors

Uterine cervix carcinoma is one of the most common gynaecological malignancies in Portugal, accounting for 19.6% of all tumors in women. Considerable interpatient differences in radioresponse are observed in this condition, and thus it is important to evaluate the role that tumor radiosensitivity may play in determining treatment efficacy. The demonstration that some tumors are more radiosensitive than others may allow the selection of a subgroup that will need adjuvant therapy. The objective of this work was to verify the predictive value of DNA content and G2 phase fraction, evaluated by flow cytometry, on the outcome of fractionated radiotherapy. A significant radiation induced in G2 block was observed after one week of treatment, both in aneuploid and diploid tumors.

1176 Uterine sarcomas: Prognostic factors and treatment modalities

From 1974 to 1992, 65 patients with uterine sarcomas were referred to Instituto Portugues de Oncologia—Porto. All patients were retrospectively staged according to accepted UICC criteria. The distribution by histologic type was the following: Leiomyosarcoma (LMS)—33 patients (50.8%); mullerian mixed mesodermal tumor (MMM)—14 patients (21.5%); endometrial sarcoma (ES)—16 patients (24.6%) and other histologies—2 patients (3.1%). Overall survival at 2 and 5 years was 74% and 58%, respectively. Age at presentation, initial symptoms, parity and associated medical conditions were recorded. Overall survival (OS) and disease-free survival (DFS) were analysed by histologic type, hormonal status, tumor extension and treatment. Tumor extension and hormonal status were the most important factors in predicting survival (P