Elisa Lazzarich
University of Eastern Piedmont
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Featured researches published by Elisa Lazzarich.
Clinical Transplantation | 2008
Piero Stratta; Veronica Morellini; Claudio Musetti; Ernesto Turello; Daniela Palmieri; Elisa Lazzarich; Tiziana Cena; Corrado Magnani
Abstract: Background: Post‐transplant malignancies (PTM) occur in a percentage as high as 50% in patients followed 20 yr and have become a main cause of mortality and are expected to be the first cause of death within the next 20 yr in kidney transplant recipients.
Critical Reviews in Oncology Hematology | 2011
Piero Stratta; Luciana Gravellone; Tiziana Cena; Davide Rossi; Gianluca Gaidano; Roberta Fenoglio; Elisa Lazzarich; Marco Quaglia; Andrea Airoldi; Cristina Bozzola; Guido Monga; Guido Valente; Caterina Canavese; Corrado Magnani
Monoclonal components (MC) formed by chains/fragments of intact/truncated globulin components produced in different lymphoproliferative diseases are responsible for monoclonal immunoglobulin deposition disease (MIDD) and consequent tissue damage by organized (amyloid fibrils) or non-organized (amorphous) deposits. The kidneys are the most commonly affected organs in MIDD, and renal failure represents an important adverse factor for prognosis. The renal outcome and the role of renal pathology in diagnosing MIDD was evaluated in 289 elderly patients with multiple myeloma (MM, n=115) and monoclonal gammopathy (MGUS, n=174). Renal impairment was the only significant risk factor for patient death, while significant risk factors for renal impairment were diabetes (HR 3.65, 95% CI: 2.08-6.41), light chain (LC) proteinuria (HR 2.18; 95% CI: 1.10-4.32) and type of MC (p=0.0019). Renal pathology documented MIDD in 12/30 cases (40%): six cases of AL-amyloidosis, two of LC disease, one of heavy chain disease and three of cast nephropathy, as well as four cases of glomerulonephritis, eight of arteriolosclerosis and six of normal picture. Main conclusions are that diabetes, sharing common glomerular damage with LC disease, is the strongest risk factor for progression of renal disease, and glomerular proteinuria or heavy LC proteinuria should raise a strong suspicion index of MIDD and prompt pathology assessment to reach the correct diagnosis.
Clinical Transplantation | 2014
Marco Quaglia; Claudio Musetti; Gian Marco Ghiggeri; Giovanni B. Fogazzi; Fabio Settanni; Renzo Boldorini; Elisa Lazzarich; Andrea Airoldi; Cristina Izzo; Mara Giordano; Piero Stratta
Patients with a rare genetic disease may receive renal transplantation (KTx) without a correct diagnosis of causal nephropathy and therefore develop unexpected and even severe complications. The aim of the study was to describe the cases of rare genetic disorders diagnosed after KTx, in order to draw clinical lessons for the transplant physician.
Kidney International | 2009
Piero Stratta; Roberta Fenoglio; Marco Quaglia; Elisa Lazzarich; Andrea Airoldi
To the Editor: In a recent interesting review regarding etiologic mechanisms of stone formation,1 no mention was made of the role of medullary sponge kidney (MSK), characterized by ectasia and cystic formation in the medullary collecting precalyceal ducts.
Asian Journal of Andrology | 2012
Paolo Gontero; Marco Oderda; Claudia Filippini; Francesco Fontana; Elisa Lazzarich; Piero Stratta; Ernesto Turello; Alessandro Tizzani; Bruno Frea
Reduced cavernosal arterial inflow has been hypothesized to be the likely cause of erectile dysfunction after kidney transplants in recipients revascularized through end-to-end anastomosis to the internal iliac artery, suggesting that end-to-side anastomosis at the external iliac artery is preferable. The aim of this study was to prospectively evaluate the effect of the use of the external iliac artery on erectile function, hormone profiles and penile blood flow by evaluating changes in penile colour Doppler ultrasound parameters in a consecutive series of 22 recipients before and after end-to-side external iliac artery transplantation. The mean International Index of Erectile Function-Erectile Function (IIEF-EF) domain score decreased significantly 3 months after transplant (18.09±6.33 vs. 22.50±7.09, P=0.01). The reduction in peak systolic velocity (PSV) was significant for the cavernous artery homolateral to the side of transplant (42.60±18.77 vs. 52.01±19.91, P=0.01). The mean postoperative end diastolic velocity (EDV) did not differ significantly from the preoperative value (P=0.74). No statistical differences were found in the serum levels of testosterone or prolactin. Kidney grafts anastomosed at the external iliac artery produced significant (P=0.01) reductions in arterial inflow at the homolateral cavernosal artery that remained above the normal threshold. Whether these haemodynamic changes can explain the worsening of postoperative erectile function remains to be proven.
European Urology | 2010
Andrea Airoldi; Alessandro Volpe; Michele Billia; Giansilvio Marchioro; Roberta Fenoglio; Elisa Lazzarich; GianMario Sacchetti; Cinzia Baiocco; Eugenio Inglese; Alberto Menegotto; Carlo Terrone; Piero Stratta
Renal transplantation is the treatment of choice for patients with end-stage renal disease and it has already been described in the literature in patients with orthotopic neobladders, mostly in the paediatric population. We report the first case of a living-donor renal graft in an adult patient with a orthotopic neobladder that was performed after radical cystectomy for urinary tuberculosis and reflux nephropathy. This patient experienced urologic and metabolic complications since the early posttransplant period.
American Journal of Kidney Diseases | 2007
Piero Stratta; Elisa Lazzarich; Caterina Canavese; Cristina Bozzola; Guido Monga
Journal of Nephrology | 2008
Caterina Canavese; Mereu Mc; Aime S; Elisa Lazzarich; Roberta Fenoglio; Marco Quaglia; Piero Stratta
Current Medicinal Chemistry | 2009
Piero Stratta; Eirini Karvela; Caterina Canavese; Marco Quaglia; Elisa Lazzarich; Roberta Fenoglio; Patrizia Pergolini; Giorgio Bellomo; Tiziana Cena; Corrado Magnani
American Journal of Kidney Diseases | 2007
Piero Stratta; Sara Barbieri; Elisa Lazzarich; Roberta Fenoglio; Marco Quaglia