Emile Al-Farhan

High yield synthesis of the parent C-unsubstituted calix[4]resorcinarene octamethyl ether

Treatment of 2,4-dimethoxybenzyl alcohol with trifluoroacetic acid (TFA, 5% in CHCl3) affords, in almost quantitative yield calix[4]resorcinarene octamethyl ether, which on demethylation and acetylation yields the derived octa-acetate.

Cyclo-oligomerization of veratryl alcohol with triflouroacetic acid

Abstract Treatment of veratryl alcohol with a dilute solution of triflouroacetic acid in chloroform yields a mixture of oligomers. Four major products have been separated and identified as the new cyclohexaveratrylene 6 and cyclopentaveratrylene 5 , in addition to the known cyclic tetramer 4 and cyclic trimer 3

A simple synthesis of cyclotribromoveratrylene (CTBV) : an extractive of the red alga Halopytis pinastroides

Abstract Treatment of 5-bromoveratryl alcohol with trifluoroacetic acid yields 1,6,11-tribromo-10,15-dihydro-2,3,7,8,12,13-hexamethoxy-5H-tribenzo [a,d,g]cyclononene(CTBV), previously isolated from the red alga, Halopytis pinastroides .