Emrah Soylu

Effect of platelet-rich plasma on fibrocartilage, cartilage, and bone repair in temporomandibular joint.

PURPOSE The purpose of the present study was to explore the potential use of platelet-rich-plasma (PRP) in the treatment of temporomandibular joint osteoarthritis (TMJ-OA). MATERIALS AND METHODS Surgical defects were created bilaterally on the condylar fibrocartilage, hyaline cartilage, and bone to induce an osteoarthritic TMJ in rabbits. PRP was applied to the right joints of the rabbits (PRP group), and the left joints received physiologic saline (control group). After 4 weeks, the rabbits were sacrificed for histologic and scanning electron microscopy (SEM) examinations. The data were analyzed statistically. RESULTS The new bone regeneration was significantly greater in the PRP group (P < .011). Although the regeneration of the fibrocartilage and hyaline cartilage was greater in the PRP group, no statistically significant difference was found between the 2 groups. SEM showed better ultrastructural architecture of the collagen fibrils in the PRP group. CONCLUSIONS PRP might enhance the regeneration of bone in TMJ-OA.

A reactive lesion (pyogenic granuloma) associated with dental implant: a case report.

D ental osseointegrated implants are made of titanium, which is a tissuefriendly and osseointegratable material; the implants have been widely used in preprosthetic surgery. Dental plaque, inadequate oral hygiene, traumatic occlusion, and anatomic drawbacks can cause complications associated with dental implants resulting in peri-implantitis and implant failure. However, gingival reactive lesions like Pyogenic granuloma (PG) or peripheral giant cell granuloma (PGCG) are thought of as common lesions in the natural dentition while such lesions in association with dental implants are uncommon. Pyogenic granuloma is a common, inflammatory hyperplasia of the oral cavity. Although the term ‘‘pyogenic’’ is used, PG is not an infectious lesion. PG usually occurs as a response to different stimulating factors such as local trauma or irritation, iatrogenic and hormonal factors. Because of the female hormone factor it has very high incidence in young females, principally in the second decade of life. Clinically, PG presents as a painless, smooth, or lobulated shape. It is classed as a hemorrhagic lesion because of its vascular structure and its color ranges from pink to dark red. In addition, it bleeds very easily when touched. Sometimes its surface may be covered by a pseudo-membrane due to secondary ulcerations. There are only two case reports in the literature that describe PG associated with dental implants. The aim of this paper is to present the case of a patient with PG in association with dental implant, which had been inserted after bone splitting.

Acute fetal distress following tooth extraction and abscess drainage in a pregnant patient with maxillofacial infection

Oral infections have been implicated in adverse pregnancy outcomes such as pre-eclampsia, premature delivery and growth retardation. A 28-year-old and 9 months pregnant otherwise healthy woman with a complaint of facial swelling and dental pain was referred to the Department of Oral and Maxillofacial Surgery. Oral examination revealed perimandibular and masticator space infection related to the left mandibular third molar tooth. Eight hours after surgical intervention, fetal distress developed. The patient was immediately taken into surgery and a male baby delivered by Caesarean section. The baby was then admitted to the intensive care unit. On the twelfth day of his admission, the baby was discharged in good health. Severe maxillofacial infection in pregnancy is a medically complicated situation which should be treated by an oral and maxillofacial surgeon in consultation with an obstetric and gynaecology service.