Enid Zuckerman
Memorial Sloan Kettering Cancer Center
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Enid Zuckerman.
Cancer | 2005
Arti Hurria; Supriya Gupta; Marjorie Glass Zauderer; Enid Zuckerman; Harvey J. Cohen; Hyman B. Muss; Miriam B. Rodin; Katherine S. Panageas; Jimmie C. Holland; Leonard Saltz; Mark G. Kris; Ariela Noy; Jorge Gomez; Ann A. Jakubowski; Clifford A. Hudis; Alice B. Kornblith
As the U.S. population ages, there is an emerging need to characterize the “functional age” of older patients with cancer to tailor treatment decisions and stratify outcomes based on factors other than chronologic age. The goals of the current study were to develop a brief, but comprehensive, primarily self‐administered cancer‐specific geriatric assessment measure and to determine its feasibility as measured by 1) the percentage of patients able to complete the measure on their own, 2) the length of time to complete, and 3) patient satisfaction with the measure.
Cancer | 2003
Alice B. Kornblith; James E. Herndon; Raymond B. Weiss; Chunfeng Zhang; Enid Zuckerman; Sylvia Rosenberg; Magriet Mertz; David K. Payne; Mary Jane Massie; James F. Holland; Patti Wingate; Larry Norton; Jimmie C. Holland
The long‐term impact of breast carcinoma and its treatment was assessed in 153 breast carcinoma survivors previously treated on a Phase III randomized trial (Cancer and Leukemia Group B [CALGB 7581]) a median of 20 years after entry to CALGB 7581.
Journal of the American Geriatrics Society | 2006
Arti Hurria; Carol Rosen; Clifford Hudis; Enid Zuckerman; Katherine S. Panageas; Mark S. Lachs; Matthew Witmer; Wilfred G. van Gorp; Monica Fornier; Gabriella D'Andrea; Mark M. Moasser; Chau Dang; Catherine Van Poznak; Anju Hurria; Jimmie C. Holland
OBJECTIVES: To report on the longitudinal cognitive functioning of older women receiving adjuvant chemotherapy for breast cancer.
Psycho-oncology | 2000
Jean M. Donnelly; Alice Kornblith; Stewart Fleishman; Enid Zuckerman; George Raptis; Clifford A. Hudis; Nicola Hamilton; David K. Payne; Mary Jane Massie; Larry Norton; Jimmie C. Holland
A single‐arm pilot study explored the feasibility of adapting in Interpersonal Psychotherapy (IPT) by telephone to reduce psychological distress and to enhance coping during cancer treatment. Therapy focuses on role transitions, interpersonal conflicts, and grief precipitated by cancer. Breast cancer patients receiving high‐dose chemotherapy received weekly sessions with a psychologist throughout chemotherapy and for 1 month afterwards. Patients could invite one ‘partner’ to receive individual telephone IPT. Psychosocial functioning was assessed using standardized measures at study entry, after chemotherapy, and following telephone IPT.
Journal of the American Geriatrics Society | 2007
Arti Hurria; Stuart M. Lichtman; Jonathan Gardes; Daneng Li; Sewanti Limaye; Sujata Patil; Enid Zuckerman; William P. Tew; Paul A. Hamlin; Ghassan K. Abou‐Alfa; Mark S. Lachs; Eva Kelly
OBJECTIVES: To integrate the principles of geriatric assessment into the care of older patients with cancer in order to identify vulnerable older adults and develop interventions to optimize cancer treatment.
Journal of Clinical Oncology | 1993
Alice B. Kornblith; D R Hollis; Enid Zuckerman; A P Lyss; George P. Canellos; M R Cooper; J E Herndon nd; C A Phillips; J Abrams; Joseph Aisner
PURPOSE The impact of the side effects of megestrol acetate on the quality of life of noncachectic women with advanced breast cancer was studied in a dose-response clinical trial of the Cancer and Leukemia Group B (CALGB 8741). Side effects of appetite increase and weight gain at higher doses were predicted to have a negative effect on quality of life. PATIENTS AND METHODS Stage IV breast cancer patients were randomized to receive either 160, 800, or 1,600 mg/d of megestrol acetate. Quality of life was assessed in 131 patients at trial entry and at 1 and 3 months while on treatment, by telephone interview, using the following measures: the Functional Living Index-Cancer (FLIC), Rand Functional Limitations Scale, Rand Mental Health Inventory (MHI), the Body Image Subscale, and linear analog scales of drug side effects. RESULTS At 3 months, women treated with 160 mg/d reported less severe side effects (P < .0005), better physical functioning (FLS, P < .0005), less psychologic distress (MHI, P = .008), and an improvement in overall quality of life (FLIC, P = .003) from the time of study entry as compared with those treated with 1,600 mg/d. Patients who received the 800-mg/d dose fell between the low- and high-dose arms in reported intensity of drug side effects, but responded similarly to those in the 160-mg/d group in terms of physical functioning, psychologic distress, and overall quality of life. CONCLUSION Unless additional follow-up data demonstrate a survival advantage at higher doses, the 160-mg/d dose is optimal, achieving maximal treatment effect with the fewest side effects and better quality of life.
Journal of Clinical Oncology | 2009
Arti Hurria; Daneng Li; Kurt Hansen; Sujata Patil; Ravi Gupta; Christian J. Nelson; Stuart M. Lichtman; William P. Tew; Paul A. Hamlin; Enid Zuckerman; Jonathan Gardes; Sewanti Atul Limaye; Mark S. Lachs; Eva Kelly
PURPOSE To determine the predictors of distress in older patients with cancer. PATIENTS AND METHODS Patients age >or= 65 years with a solid tumor or lymphoma completed a questionnaire that addressed these geriatric assessment domains: functional status, comorbidity, psychological state, nutritional status, and social support. Patients self-rated their level of distress on a scale of zero to 10 using a validated screening tool called the Distress Thermometer. The relationship between distress and geriatric assessment scores was examined. RESULTS The geriatric assessment questionnaire was completed by 245 patients (mean age, 76 years; standard deviation [SD], 7 years; range, 65 to 95 years) with cancer (36% stage IV; 71% female). Of these, 87% also completed the Distress Thermometer, with 41% (n = 87) reporting a distress score of >or= 4 on a scale of zero to 10 (mean score, 3; SD, 3; range, zero to 10). Bivariate analyses demonstrated an association between higher distress (>or= 4) and poorer physical function, increased comorbid medical conditions, poor eyesight, inability to complete the questionnaire alone, and requiring more time to complete the questionnaire. In a multivariate regression model based on the significant bivariate findings, poorer physical function (increased need for assistance with instrumental activities of daily living [P = .015] and lower physical function score on the Medical Outcomes Survey [P = .018]) correlated significantly with a higher distress score. CONCLUSION Significant distress was identified in 41% of older patients with cancer. Poorer physical function was the best predictor of distress. Further studies are needed to determine whether interventions that improve or assist with physical functioning can help to decrease distress in older adults with cancer.
Journal of the American Geriatrics Society | 2006
Arti Hurria; Anju Hurria; Enid Zuckerman; Katherine S. Panageas; Monica Fornier; Gabriella D'Andrea; Chau Dang; Mark M. Moasser; Mark Robson; Andrew D. Seidman; Violante Currie; Catherine VanPoznak; Maria Theodoulou; Mark S. Lachs; Clifford Hudis
OBJECTIVES: To examine the toxicity experienced by a cohort of older women receiving adjuvant chemotherapy for breast cancer and the longitudinal effect on their functional status and quality of life (QOL).
Health Psychology | 2001
Christine L. Cameron; David Cell; James E. Herndon; Alice B. Kornblith; Enid Zuckerman; Edward S. Henderson; Raymond B. Weiss; M. Robert Cooper; Richard T. Silver; Louis A. Leone; George P. Canellos; Bruce A. Peterson; Jimmie C. Holland
Persistent symptoms of nausea, distress, and vomiting triggered by reminders of cancer treatment were examined among 273 Hodgkins disease survivors, 1 to 20 years posttreatment. Prevalence rates were high for distress and nausea but low for vomiting. Retrospective report of anticipatory symptoms during treatment was the strongest predictor of persistent symptoms, suggesting that treatment-induced symptoms are less likely to persist if conditioning does not occur initially. Time since treatment was also a significant predictor, with patients more recently treated more likely to experience persistent symptoms. Thus, an explanatory model based on classical conditioning theory successfully predicted presence of persistent symptoms. Symptoms also were associated with ongoing psychological distress, suggesting that quality of life is diminished among survivors with persistent symptoms. Recommendations for prevention and treatment of symptoms are discussed.
Cancer | 1992
Abbe J. Janov; James R. Anderson; David Cella; Enid Zuckerman; Alice B. Kornblith; Jimmie C. Holland; Arlene F. Kanfor; Frederick P. Li
Background. Pregnancy outcome was reported by 139 survivors of advanced Hodgkin disease treated on nine protocols of Cancer and Leukemia Group B from 1966 to 1986.