Eran Peleg

Optimal Fixation of Acute Scaphoid Fractures: Finite Element Analysis

PURPOSE The hypothesis of this study was that more stable fixation of acute scaphoid fractures may be achieved by a screw placed perpendicular to the fracture plane than along the long axis of the scaphoid, as previously suggested. We examined this assumption on different fracture patterns using a finite element analysis model. METHODS A computed tomography scan of an intact scaphoid of a young man provided the data set for all fracture models. We used semiautomatic segmentation to create 3-dimensional computer models of the 3 simple fracture configurations: oblique, transverse waist, and proximal fractures, according to the Herbert classification. Each fracture type was analyzed, using finite elements, for its biomechanical response to 2 types of virtual fixation: a screw placed either perpendicular to the fracture plane or centrally along the long axis of the scaphoid. We measured motion at the fracture plane (in millimeters) and strain in the screw threads (in millipascals). RESULTS Considerably less motion was measured at the fracture plane with the perpendicular screw compared with the long axis screw, especially in the oblique-type fractures: (1) Herbert-type B1 oblique fracture mean motion of 0.05 mm (+/-0.03) for the perpendicular screw versus 0.28 mm (+/-0.05) for the long axis screw; (2) B2 transverse waist fracture mean motion of 0.06 mm (+/-0.03) for the perpendicular screw versus 0.18 mm (+/-0.06) for the long axis screw; and (3) B3 proximal fracture mean motion of 0.07 mm (+/-0.01) for the perpendicular screw versus 0.28 mm (+/-0.011) for the long axis screw. Higher strains were measured on the screw placed perpendicular to the fracture. CONCLUSIONS According to this model, higher fixation stability is achieved when the scaphoid is fixated perpendicular to the fracture. In transverse waist fractures, a centrally placed screw will also be perpendicular to the fracture, which explains the results of previous models.

Optimal Fixation of Oblique Scaphoid Fractures: A Cadaver Model

PURPOSE Acute scaphoid fractures are commonly fixed with headless cannulated screws positioned in the center of the proximal fragment. Central placement of the screw may be difficult and may violate the scaphotrapezial joint. We hypothesize that placement of the screw through the scaphoid tuberosity will achieve perpendicular fixation of an oblique waist fracture and result in more stable fixation than a screw in the center of the proximal fragment. METHODS We designed oblique osteotomies for 8 matched pairs of cadaver scaphoids and fixed each specimen with a headless cannulated screw. In 1 specimen, we positioned the screw at the center of the proximal fragment; we placed its matched pair perpendicular to the fracture. The perpendicular screw was directed through the scaphoid tuberosity. We placed the specimen under the increasing load of a pneumatically driven plunger. We compared stiffness, load, distance at failure, and mechanism of failure between the central and perpendicular screw groups. RESULTS We found no difference between groups. Stiffness was identical in both groups (131 N/mm) and load to failure was similar (central screw, 137 N vs perpendicular screw, 148 N). CONCLUSIONS In this biomechanical model of an unstable scaphoid fracture, we found that similar stability of fixation had been achieved with a screw perpendicular to the fracture plane with entry through the tuberosity, compared with a screw in a central position in the proximal fragment. This study suggests that placing the screw through the tuberosity, perpendicular to a short oblique fracture, will not impair fixation stability. CLINICAL RELEVANCE Percutaneous fixation of scaphoid fractures has become popular although it is technically challenging. An easier distal approach through the tuberosity, without violating the scaphotrapezial joint, may not impair the fixation stability of an oblique fracture.

Patient specific quantitative analysis of fracture fixation in the proximal femur implementing principal strain ratios. Method and experimental validation

Computational patient-specific modeling has the potential to yield powerful information for selection and planning of fracture treatments if it can be developed to yield results that are rapid, focused and coherent from a clinical perspective. In this study we introduce the utilization of a principal strain fixation ratio measure (SR) defined as the ratio of principal strains that develop in a fixated bone relative to the principal strains that develop in the same bone in an intact state. The SR field output variable is theoretically independent of load amplitude and also has a direct clinical interpretation with SR<1-a representing stress shielding and SR>1+b representing overstressed bone. A combined experimental and numerical study was performed with cadaveric proximal femora (n=6) intact and following fracture fixation to quantify the performance of the SR variable in terms of accuracy and sensitivity to uncertainties in density-elasticity relationships and load amplitude as model input variables. For a given axial compressive force the SR field output variable was found to be less sensitive to changes in density-elasticity relationships and the response function to be more accurate than strain values themselves; errors were reduced by 44% on comparing SR with strain in the fixated model. In addition, the experimental data confirmed the assumption that the SR values behave independent of load amplitude. The load independent behavior of SR and its direct clinical interpretation may ultimately provide an appropriate and easily understood comparative computational measure to choose between patient specific fracture fixation alternatives.

Can a partial volume edge effect reduction algorithm improve the repeatability of subject-specific finite element models of femurs obtained from CT data?

The reliability of patient-specific finite element (FE) modelling is dependent on the ability to provide repeatable analyses. Differences of inter-operator generated grids can produce variability in strain and stress readings at a desired location, which are magnified at the surface of the model as a result of the partial volume edge effects (PVEEs). In this study, a new approach is introduced based on an in-house developed algorithm which adjusts the location of the models surface nodes to a consistent predefined threshold Hounsfield unit value. Three cadaveric human femora specimens were CT scanned, and surface models were created after a semi-automatic segmentation by three different experienced operators. A FE analysis was conducted for each model, with and without applying the surface-adjustment algorithm (a total of 18 models), implementing identical boundary conditions. Maximum principal strain and stress and spatial coordinates were probed at six equivalent surface nodes from the six generated models for each of the three specimens at locations commonly utilised for experimental strain guage measurement validation. A Wilcoxon signed-ranks test was conducted to determine inter-operator variability and the impact of the PVEE-adjustment algorithm. The average inter-operator difference in stress values was significantly reduced after applying the adjustment algorithm (before: 3.32 ± 4.35 MPa, after: 1.47 ± 1.77 MPa, p = 0.025). Strain values were found to be less sensitive to inter-operative variability (p = 0.286). In summary, the new approach as presented in this study may provide a means to improve the repeatability of subject-specific FE models of bone obtained from CT data.

Implementing metal detector technology and a navigation system in the removal of shrapnel

Introduction: The removal of metal shrapnel in the sub-acute phase of casualty treatment requires the utmost accuracy in detection and removal, especially when there is proximity to major neurovascular structures. Inability to successfully locate and remove retained fragments may lead to a variety of complications due to fragment migration. In this study we prove the feasibility of a new technique which uses metal detector technology combined with a surgical navigation system, resulting in improved accuracy and decreased operating time. Methods: In each of the experiments, 6 metal nuts were inserted into a dummy leg to simulate shrapnel wounds. Two major experiments were then conducted. Experiment 1 was a comparison of two methods: (a) localization of the nuts using surgical navigation alone, and (b) localization by means of metal detector technology combined with a surgical navigation system (StealthStation® TREON® plus). Experiment 2 employed the same two methods, but this time migration of the metal fragments was introduced. The localization time was measured from incision of the dummy skin to the moment the metal fragment was touched by the searching device. Results: In experiment 1 the results showed no significant differences between the two approaches. In experiment 2 the new technique was found to significantly decrease the mean fragment localization time, taking 9.6 seconds (±7.2 seconds) as compared to 26.4 seconds (±13.8 seconds) when using the regular technique. Conclusion: Combining a metal detector probe and a surgical navigation system was found to significantly decrease operating time and increase the surgeons confidence, especially in cases where migration of the metal fragment occurred during searching and extraction.

Three-Dimensional Analysis of Acute Scaphoid Fracture Displacement: Proximal Extension Deformity of the Scaphoid

Background: Our goal was to analyze the movement of acute scaphoid waist fracture fragments and adjacent bones in a common coordinate system. Our hypothesis was that the distal scaphoid fragment flexes and pronates and the proximal fragment extends. Methods: Computed tomography (CT) scans of patients diagnosed with an acute scaphoid waist fracture were evaluated using a 3-dimensional (3D) model. The scans of 57 nondisplaced and 23 displaced fractures were compared with a control group of 27 scans showing no pathological involvement of the wrist. Three anatomical landmarks were labeled on the distal and proximal fragments of the scaphoid, the lunate, and the trapezium. Each set of labels formed a triangle representing the bone or fragment. Four landmarks were labeled on the distal radial articular surface and used to create a common coordinate system. The position of each bone or fragment was calculated in reference to these coordinates. Results: The displaced fracture group showed significant extension, supination, and volar translation of the proximal scaphoid fragment when compared with the other groups. The lunate tended toward a supinated position, which was not statistically significant. The distal scaphoid fragment and the trapezium showed no movement. Conclusions: In acute displaced scaphoid fractures, it is the proximal fragment that displaces and should be reduced. Clinical Relevance: The typical “humpback” deformity is actually a “proximal extension” deformity, the consequence of displacement of the proximal fragment of the scaphoid (with the lunate). Manipulating only the proximal fragment (with the lunate) may be technically easier and more effective than manipulating both fragments.

Pediatric supracondylar humerus fractures: effect of bone–implant interface conditions on fracture stability

BackgroundClosed reduction and percutaneous fixation with Kirschner wires (KWs) is the standard of care of pediatric supra-condylar humerus fractures (SCHFs). Failure modes leading to loss of reduction are not clear and have not been quantified. Multiple factors may weaken the KW–bone interface bonding conditions. To the best of our knowledge, the possible effect of this decrease on different KW configurations and fracture stability has never been studied.PurposeTo investigate the effect of bone–KW friction conditions on SCHF post-operative mechanical stability and to formulate clinical guidelines for KW configuration under different conditions.MethodsFinite element-based model of a fixated SCHF was used to simulate structure stability for two lateral divergent versus crossed lateral and medial KW configurations under varying KW–bone friction conditions.ResultsFinite element simulations demonstrated that crossed KWs provide superior stability compared with the divergent configuration when KW–bone bonding is compromised. When KW–bone bonding conditions are adequate, crossed and divergent KW configurations provide similar, sufficient fracture stability.ConclusionsUnder normal bone–implant interface conditions, the two diverging lateral KW configuration offers satisfactory mechanical stability and may be the preferred choice of SCHF fixation. When KW–bone bonding is suboptimal, as when one or more of the lateral KWs are re-drilled, addition of a medial KW should be considered in order to improve stability despite risk to ulnar nerve.

A novel field-of-view augmentation wand for C-arm computed tomography-like fluoroscopy-based intraoperative navigation new technology.

Intraoperative fluoroscopically based computed tomography, integrated with a navigation system, holds great potential for improving visualization and navigation in orthopedic procedures. However, a limited field of view generated by the fluoroscopically based computed tomography has imposed a serious limitation, especially for navigation-based procedures. The device presented in this article enables one to overcome the limitation of the small field of view. The device has been evaluated in vitro by five physicians and has been used successfully in one clinical case. In general, we have developed a simple, low-cost in-house device that helps overcome an intrinsic limitation of high-cost systems.

Three-dimensional comparison of alternative screw positions versus actual fixation of scaphoid fractures

PURPOSE The recommended technique for the fixation of a scaphoid waist fracture involves a headless compression screw placed in the proximal fragment center. This is usually accomplished by placing a longitudinal axis screw as visualized by fluoroscopy. The screw length has been shown to have a biomechanical advantage. An alternative to these options, which has been debated in the literature, is a screw placed perpendicular to the fracture plane and in its center. The perpendicular screw may have a biomechanical advantage despite the fact that it may be shorter. This study examined the differences in location and length in actual patients between a screw in the center of the proximal fragment with a longitudinal axis screw, and the actual fixating screw. These were then compared to a perpendicular axis screw. METHODS Pre- and post-operative CT scans of 10 patients with scaphoid waist fractures were evaluated using a 3D computer model. Comparisons were made between the length, location and angle of actual and virtual screw alternatives; namely, a screw along the central third of the proximal fragment (central screw axis) where the scaphoid longitudinal axis was calculated mathematically (longitudinal screw axis) and a screw placed at 90° to the fracture plane and in its center (perpendicular screw axis). RESULTS The longitudinal axis screw was found to be significantly longer than the other axes (28.3mm). There was a significant difference between the perpendicular axis screw and the location and angle of the other screw axis, but it was only shorter than the longitudinal screw (23.6mm versus 25.5mm for the actual screw; ns.). CONCLUSIONS A computed longitudinal axis screw is longer than a central or actual screw placed longitudinally by visual inspection by the surgeon. Although it needs to be placed using computer assisted (CAS) techniques, it may have the biomechanical advantages of a longer screw in a similar trajectory. The perpendicular screw was found to be significantly different in position and angle but not shorter than the actually placed screw. It has biomechanical advantages and does not require visualization with CAS methods, making it the more attractive alternative.