Ercan Kaya

Investigation of the Presence of Biofilms in Chronic Suppurative Otitis Media, Nonsuppurative Otitis Media, and Chronic Otitis Media with Cholesteatoma by Scanning Electron Microscopy

Objective. Biofilms have been shown to play a major role in the pathogenesis of otolaryngologic infections. However, very limited studies have been undertaken to demonstrate the presence of biofilms in tissues from patients with chronic otitis media (COM) with or without cholesteatoma. Our objective is to study the presence of biofilms in humans with chronic suppurative and nonsuppurative otitis media and cholesteatoma. Study Design. In all, 102 tissue specimens (middle ear, mastoid tissue, and ossicle samples) were collected during surgery from 34 patients. Methods. The samples were processed for the investigation of biofilms by scanning electron microscopy (SEM). Results. Our research supports the hypothesis in which biofilms are involved in chronic suppurative otitis media, cholesteatoma, and, to a lesser degree, chronic nonsuppurative otitis media. There were higher rates in hypertrophic and granulated tissue samples than in normal mucosa. In addition, the presence of biofilms was significantly higher in the middle ear mucosa compared with the mastoid and ossicle samples. Conclusion. In the clinic, the careful use of topical or systemic antimicrobials is essential, and, during surgery, hypertrophic tissue must be carefully removed from normal tissue.

Evaluation of nasal airway alterations associated with septorhinoplasty by both objective and subjective methods

The aim of functional septorhinoplasty is to create an esthetically elegant nose and harmony in the face by preserving nasal function as well as maintaining or restoring adequate airway. Since nasal complaints are usually subjective, it may be difficult to evaluate the functions objectively. In the present study, we aimed to investigate the alterations in nasal function associated with septorhinoplasty by using both objective and subjective methods. The study population consisted of 40 patients who underwent septorhinoplasty and 40 healthy controls. Before and after the operation, visual analog scale, acoustic rhinometry, rhinomanometry, and Odiosoft-Rhino test were applied to all patients and controls. There were significant differences in all parameters both before and after the operation. While a significant difference was obtained between the patient and control groups in terms of preoperative values, no significant difference was found between postoperative values of these groups. Both objective and subjective methods are important in evaluations.

Use of cone beam computed tomography in otolaryngologic treatments

Cone beam computed tomography (CBCT) allows us to evaluate 3-dimensional (3D) morphology of the maxillofacial skeleton and also used in dentomaxillofacial imaging to solve complex diagnostic and treatment planning problems such as craniofacial fractures, temporamandibular dysfunctions or sinus imaging. CBCT uses a rectangular or round 2D detector, which allows a single rotation of the gantry to generate a scan of the entire region of interest. Technological and application-specific factors such as development of compact, relatively low-cost, high-quality, large, flat-panel detector arrays; the availability of low-cost computers with processing power sufficient for cone beam image reconstruction; the fabrication of highly efficient radiograph tubes capable of multiple exposures necessary for cone beam scanning at prices lower than those currently used for fan beam CT; and limited volume scanning (e.g., head and neck) eliminating the need for subsecond gantry rotation speeds make this possible. The objective of this study is to review published evidence for CBCT having an important role in ORL treatments. We aimed to review all the available literature about the CBCT imagination in ORL treatments. Systematic literature search was performed using PubMed and Ovid. Additional literature was retrieved from reference lists in the articles. Systematic analysis of the literature from 1998 to 2010 was performed. A total of 40 abstracts were evaluated independently by two members of the project group, and 38 articles were included in the review.

Use of rhinomanometry in common rhinologic disorders.

Rhinomanometry is a functional test of nasal aerodynamics that measures transnasal airflow and the pressure gradient allowing nasal resistance to be calculated from these data. Three methods of rhinomanometry that are currently in use are anterior rhinomanometry, posterior (peroral) rhinomanometry and postnasal (pernasal) rhinomanometry. The usefulness of this method has increased owing to the development of technology and use of microcomputers connected to the measuring devices. Rhinomanometry can be used for: clinical evaluation of the symptom of nasal obstruction; research in nasal physiology; allergy challenge testing; pre- and post-treatment assessments of surgical or medical therapy; and evaluation of patients with sleep apnea.

Three layer interlocking: a novel technique for repairing a nasal septum perforation.

Objective: Many techniques to repair a septal perforation using local flaps with or without an interpositioning graft with various rates of success have been described. Our aim was to describe a new and relatively easy technique for repairing these perforations. Methods: Twenty-two patients with nasal septal perforations smaller than 2 cm in diameter were operated on between 2010 and 2012 at Eskişehir Osmangazi University. The described 3-layer interlocking method was applied to repair the septal perforation in all of the cases. Results: Twenty-two patients were operated on using this technique. The follow-up time ranged from 30 months to 10 months, with a mean follow-up time of 20.9 months. In 19 of the 22 patients, complete closure of the perforation was achieved (86.3%). We did not encounter any early or late postoperative complications. Conclusion: A novel technique that uses a temporalis fascia-conchal cartilage complex as an interpositioning material to repair septal perforations is described. This complex was endoscopically introduced to the perforation after elevating the edges of the perforation. We concluded that the low morbidity, short operating time, and high success rate make this technique a good choice for repairing small- to medium-sized perforations.

The round window diameter in congenital aural atresia and comparison with sensorineural hearing loss and control group.

Objective The aim of this study was to measure round window (RW) diameters in patients with congenital aural atresia (CAA) or sensorineural hearing loss (SNHL) and a normal control group and to analyze whether differences exist between these groups. Methods Temporal bone computed tomographic scans of 12 patients with CAA (5 males, 7 females) aged 1 to 50 years (median age, 6 years), 12 patients with SNHL (8 males, 4 females) aged 2 to 32 years (median age, 5 years), and 11 patients (3 males, 7 females) aged 2 months to 53 years (median age, 8 years) randomly selected from a pool of patients with unilateral chronic otitis media or cholesteatoma were reviewed. We measured RW diameter on oblique reconstruction planes. To prevent possible individual differences, skull width was measured. Results There were no statistically significant differences between all groups for skull width. Both RW diameter and RW membrane width were found smaller in the CAA group than both SNHL group and control group with statistical significance, whereas there were no statistically significant differences between the SNHL group and the control group. Conclusions We found that both the RW diameter and RW membrane width in CAA were smaller than those in the control group. If this finding is supported in future studies, the production of floating mass transducer with different sizes may be useful. We suggest that RW diameter should be measured in each patient before operation and thus a floating mass transducer with the appropriate caliber should be chosen.

Survival of diced and block cartilage grafts in combination with injectable calcium hydroxylapatite

Dorsal nasal irregularities after trauma, and various procedures such as excessive nasal hump resection, are major problems for patients who have undergone rhinoplasty. Many grafts have been described for the correction of dorsal nasal irregularities. In this study, we used an injectable implant, in combination with diced or block cartilage grafts, to test the efficacy of injectable calcium hydroxylapatite on the survival of diced or block cartilage grafts.

A novel technique for spreader graft placement without dorsum resection during septoplasty.

OBJECTIVE This paper presents a novel method for spreader graft placement without dorsum resection in patients who have a deviated septum with a narrow internal nasal valve angle. METHODS A Killian incision was used for the endonasal septoplasty, and all spreader grafts were harvested from excised deviated septal cartilages. Procedures were conducted under general anaesthesia at the same centre by the same surgical team that performed the endonasal procedure. Successful placement of spreader grafts was achieved endonasally. CONCLUSION Although the endonasal placement of spreader grafts seems to be more difficult than placement conducted by an open approach technique, an endonasal procedure has many advantages. Our technique provides surgeons with the opportunity to shorten operation time, obtain autologous septal graft material and secure the columellar architecture. Surgeons familiar with the classical (endonasal) septoplasty procedure can easily apply this technique to widen a narrow internal nasal valve angle, without corrupting nasal integrity.

Larenks kanserli hastalarda sağlıkta yaşam kalitesi

Health-related quality of life (QOL) is increasingly being recognized as an important issue in oncology. It is a multidimensional concept which comprises four core domains: physical functioning, psychological functioning, social interaction and diseaseand treatment-related symptoms. Quality of life is an important indicator of treatment outcome and is used increasingly as an end point in clinical trials. Patients with head and neck cancer not only have to face a life-threatening disease, they also have to deal with the impact of both the disease and its treatment on physical, psychological and social functioning. They are prone to psychosocial problems, because social interaction and emotional expression depend to a great extent upon the structural and functional integrity of the head and neck region. Clinical Research / Klinik Araflt›rma

Acoustic Analysis of Soccer Fans in Acute Phonotrauma After the Match

OBJECTIVES Acute phonotrauma is the result of sound production by shouting or straining ones voice. In this study, we aimed to investigate the acute changes in the vocal folds and voices of soccer fans who voluntarily applied to our clinic after the soccer match where they engaged in acute phonotrauma. There are no other studies in the literature conducted on a similar sample group. STUDY DESIGN This is a case-control study. METHODS Videolaryngostroboscopic (VLS) examination, acoustic voice analysis, and Voice Handicap Index (VHI) questionnaire were performed on 29 voluntary soccer fans included to the study before the match and at the first hour after the match. The values obtained were compared statistically with each other and with 29 control groups without voice pathology. RESULTS The jitter, shimmer, and normalized noise energy values measured after the match increased significantly statistically compared with the pre-match level, but harmonic noise ratio value decreased significantly (P < 0.05). VHI scores increased significantly after the match according to the pre-match scores (P < 0.05). In the VLS examinations, there was no difference in the images before and after the match. CONCLUSIONS It has been concluded that people who are using their voices loudly and intensely by shouting during the match are exposed to sound changes after the match, and if this situation becomes persistent, it may cause permanent voice pathologies. It is thought that VHI and acoustic voice analysis should be done together with VLS for diagnosis and follow-up of voice changes for which the VLS examination alone is not sufficient.