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Dive into the research topics where Eric Doelker is active.

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Featured researches published by Eric Doelker.


Journal of Membrane Science | 1980

Modelling of drug diffusion through swellable polymeric systems

Nikolaos A. Peppas; Robert Gurny; Eric Doelker; Pierre Buri

Abstract A drug diffusion model for the case of diffusion of an initially uniformly distributed drug through a polymeric matrix is presented and solved. Drug diffusion from a single surface is analyzed for the case of countercurrent diffusion of a solvent which is thermodynamically compatible with the polymer. Due to swelling, considerable volume expansion is observed leading to a moving-boundary diffusion problem. Drug concentration profiles within the polymer and drug release rates can be determined. The results are in agreement with experimental data obtained for the system of KCl distributed in hydrophilic hydroxypropyl methyl cellulose matrices, in the form of tablets.


Scientia Pharmaceutica | 2010

Intra-Articular Drug Delivery Systems for Osteoarthritis Treatment

J. Pradal; O. Jordan; C. Gabay; P. A. Guerne; M. C. Bagley; Eric Doelker; J. M. Waldburger; Eric Allémann

Cartilage lesions observed in osteoarthritis (OA) are related to an important release of cytokines. [...]


European Journal of Pharmaceutics and Biopharmaceutics | 1993

Drug-loaded nanoparticles : preparation methods and drug targeting issues

E. Alleman; Robert Gurny; Eric Doelker; Eric Allémann; E Deolker


European Journal of Pharmaceutics and Biopharmaceutics | 1995

New approach for the preparation of nanoparticles by an emulsification-diffusion method

Jean-Christophe Leroux; Eric Allémann; Eric Doelker; Robert Gurny


European Journal of Pharmaceutics and Biopharmaceutics | 1993

Drug loaded poly(lactic acid) nanoparticles produced by a reversible salting-out process : purification of an injectable dosage form

Eric Allémann; Eric Doelker; Robert Gurny


Archive | 1988

Process for preparing a powder of water-insoluble polymer which can be redispersed in a liquid phase, the resulting powder and utilization thereof

Christian Bindschaedler; Robert Gurny; Eric Doelker


Archive | 1998

Method for preparing vesicular nanocapsules

David Quintanar; Hatem Fessi; Eric Doelker; Eric Allémann


Archive | 2002

A product for use in agriculture or horticulture

Diane Zimmermann; Nathalie Nurdin; Eric Allémann; Eric Doelker; Robert Gurny; Der Drift Eric Van; Ruud Scheffer; Stefan Baum


Archive | 1996

Nanoparticles in photodynamic therapy

Robert Gurny; Eric Allémann; Jean-Christophe Leroux; Julijana Kristl; Eric Doelker


Acta pharmaceutica technologica | 1990

A new high performance data acquisition system interfacing an instrumented tablet machine to a microcomputer

A.-F. Rime; F. Lescure; D. Mordier; Robert Gurny; Eric Doelker

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