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Eric Jon Jacobsen

Pfizer

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Publication

Featured researches published by Eric Jon Jacobsen.

Bioorganic & Medicinal Chemistry Letters | 2010

1-(2-(2,2,2-trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors.

Michael B. Tollefson; Brad A. Acker; Eric Jon Jacobsen; Robert O. Hughes; John K. Walker; David Nathan Abraham Fox; Michael John Palmer; Sandra K. Freeman; Ying Yu; Brian R. Bond

1H-Pyrazolo[4,3-d]pyrimidines were previously disclosed as a potent second generation class of phosphodiesterase 5 (PDE5) inhibitors. This work explores the advancement of more selective and potent PDE5 inhibitors resulting from the substitution of 2-(2,2,2-trifluoroethoxy)ethyl at the 1 position in the so-called alkoxy pocket.

Archive | 2003

Fused bicyclic-n-bridged-heteroaromatic carboxamides for the treatment of disease

Bruce N. Rogers; David W. Piotrowski; Daniel P. Walker; Eric Jon Jacobsen; Brad A. Acker; Donn G. Wishka; Vincent E. Groppi

Archive | 2003

Azabicyclic compounds for the treatment of disease

Eric Jon Jacobsen; Jason K. Myers; Daniel P. Walker; Donn G. Wishka; Steven Charles Reitz; David W. Piotrowski; Brad A. Acker; Vincent E. Groppi

Archive | 2002

Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease

Daniel P. Walker; David W. Piotrowski; Eric Jon Jacobsen; Brad A. Acker; Donn G. Wishka; Steven Charles Reitz

Archive | 2002

Azabicyclic-substituted-heteroaryl compounds for the treatment of disease

David W. Piotrowski; Jason K. Myers; Bruce N. Rogers; Eric Jon Jacobsen; Alice L. Bodnar; Vincent E. Groppi; Daniel P. Walker; Brad A. Acker

Archive | 2007

Pyridine[3,4-b]pyrazinones

Robert O. Hughes; Andrew Simon Bell; David Brown; Dafydd R. Owen; Michael John Palmer; Christopher Phillips; David L. Brown; Yvette M. Fobian; John N. Freskos; Steven E. Heasley; Eric Jon Jacobsen; Todd Michael Maddux; Brent V. Mischke; John M. Molyneaux; Joseph B. Moon; Donald Joseph Rogier; Michael B. Tollefson; John K. Walker

Archive | 2002

N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease

Daniel P. Walker; Eric Jon Jacobsen; David W. Piotrowski; Brad A. Acker; Donn G. Wishka; Jeffrey W. Corbett; Mark R. Rauckhorst; Vincent E. Groppi

Bioorganic & Medicinal Chemistry Letters | 2010

1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

Michael B. Tollefson; Brad A. Acker; Eric Jon Jacobsen; Robert O. Hughes; John K. Walker; David Nathan Abraham Fox; Michael John Palmer; Sandra K. Freeman; Ying Yu; Brian R. Bond

Archive | 2002

Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease

Daniel P. Walker; David W. Piotrowski; Eric Jon Jacobsen; Brad A. Acker; Vincent E. Groppi

Archive | 2003

1H-pyrazole and 1H-pyrrole-azabicyclic compounds for the treatment of disease

David W. Piotrowski; Eric Jon Jacobsen; Brad A. Acker; Daniel P. Walker; Donn G. Wishka; Vincent E. Groppi

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Brad A. Acker

Pfizer

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Daniel P. Walker

Pfizer

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David W. Piotrowski

Pfizer

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Vincent E. Groppi

Pfizer

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Donn G. Wishka

Pfizer

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Jason K. Myers

Pfizer

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Bruce N. Rogers

Pfizer

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John K. Walker

Pfizer

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Michael B. Tollefson

Pfizer

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Michael John Palmer

Pfizer

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