Erik V. Carter
University of California, San Francisco
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Featured researches published by Erik V. Carter.
European Journal of Cardiovascular Nursing | 2017
Kathleen T. Hickey; Lynn V. Doering; Belinda Chen; Erik V. Carter; Robert R. Sciacca; David Pickham; Carmen Castillo; Nicole R. Hauser; Barbara J. Drew
Background: Little attention has focused on gender differences in cardiac comorbidities and outcomes in patients undergoing orthotropic heart transplant. Objective: The objective of this study was to investigate gender differences at baseline and during follow-up among heart transplant patients. Methods: An observational cohort within the NEW HEART study was evaluated to determine gender differences in relation to age, coexisting cardiac comorbidities, and outcomes. Differences were assessed by t-test, Fisher’s exact test, and logistic regression analysis. Results: Male transplant recipients (n = 238) were significantly older than female recipients (n = 92), with a greater percentage over 60 years of age (45% vs. 24%, p = 0.0006). Males were more likely to have hypertension (63% vs. 49%, p = 0.034), dyslipidemia (62% vs. 45%, p = 0.006), a history of smoking (52% vs. 35%, p = 0.009), and diabetes (42% vs. 21%, p = 0.0002). Analysis of endomyocardial biopsies obtained during the 1-year follow-up period demonstrated that women averaged more episodes of acute rejection than men (3.9 vs. 3.0, p = 0.009). While most episodes of rejection were mild, women were more likely than men to have episodes of moderate or severe rejection (14% vs. 5%, p = 0.012) and to be hospitalized for acute rejection (15% vs. 6%, p = 0.013). There were no significant differences in mortality. Conclusions: Men were more likely than women to be older and to have diabetes, dyslipidemia, hypertension, and a history of smoking. Women were more likely to experience moderate or severe allograft rejection and to be hospitalized for acute rejection. Future investigation of the reasons for these gender differences is warranted and may improve clinical care of women undergoing cardiac transplantation.
American Journal of Critical Care | 2018
Kathleen T. Hickey; Robert R. Sciacca; Belinda Chen; Barbara J. Drew; David Pickham; Erik V. Carter; Carmen Castillo; Lynn V. Doering
&NA; Background Acute allograft rejection appears to be associated with increases in QT/QTc intervals. Objectives To determine the relationship between acute allograft rejection and electrocardiogram changes in patients undergoing an orthotopic heart transplant. Methods The study population comprised 220 adult patients undergoing heart transplant and enrolled in the NEW HEART study. Electrocardiograms obtained within 72 hours of endomyocardial biopsy were analyzed; electrocardiograms obtained fewer than 10 days after transplant surgery were excluded. Repeated‐measures analysis was performed with statistical models including effects for rejection severity (mild and moderate/severe) and time trends independent of rejection status. Results The 151 male and 69 female transplant recipients (mean age [SD], 54 [13] years) had 969 biopsy/electrocardiogram pairs: 677 with no rejection, 280 with mild rejection, and 12 with moderate/severe rejection. Moderate to severe organ rejection was associated with significant increases in QRS duration (P < .001), QT (P = .009), QTc (P = .003), and PR interval (P = .03), as well as increased odds of right bundle block branch (P = .002) and fascicular block (P = .009) occurring. Conclusions Moderate to severe acute allograft rejection was associated with electrocardiographic changes after transplant surgery. Studies are needed to assess the value of computerized electrocardiogram measurement algorithms for detecting acute allograft rejection.
Journal of Electrocardiology | 2017
Erik V. Carter; Carmen Castillo; Belinda Chen; Lynn V. Doering; Barbara J. Drew; Kathleen T. Hickey; David Pickham; Robert R. Sciacca
Author(s): Carter, Erik V; Castillo, Carmen; Chen, Belinda; Doering, Lynn V; Drew, Barbara J; Hickey, Kathleen T; Pickham, David; Sciacca, Robert R
Journal of Electrocardiology | 2016
Erik V. Carter; Carmen Castillo; Belinda Chen; Lynn V. Doering; Barbara J. Drew; Kathleen T. Hickey; David Pickham; Robert R. Sciacca
Author(s): Carter, Erik V; Castillo, Carmen; Chen, Belinda; Doering, Lynn V; Drew, Barbara J; Hickey, Kathleen T; Pickham, David; Sciacca, Robert R
Heart & Lung | 2012
Erik V. Carter; Kathleen T. Hickey; David Pickham; Lynn V. Doering; Belinda Chen; Patricia Harris; Barbara J. Drew
Journal of Electrocardiology | 2017
Erik V. Carter; Carmen Castillo; Belinda Chen; Lynn V. Doering; Barbara J. Drew; Kathleen T. Hickey; David Pickham; Robert R. Sciacca
Archive | 2015
Erik V. Carter
Journal of Heart and Lung Transplantation | 2015
Kathleen T. Hickey; Lynn V. Doering; Belinda Chen; Erik V. Carter; David Pickham; Carmen Castillo; Donna Mancini; Mario C. Deng; J. Kobashigawa; Barbara J. Drew
Journal of Heart and Lung Transplantation | 2014
Lynn V. Doering; Kathleen T. Hickey; Belinda Chen; F. Idemundia; Erik V. Carter; David Pickham; Carmen Castillo; Donna Mancini; Mario C. Deng; J. Kobashigawa; Barbara J. Drew
Circulation | 2010
Erik V. Carter; Kathleen T. Hickey; Belinda Chen; David Pickham; Patricia Harris; Lynn V. Doering; Barbara J. Drew