Erika A. Crawford

Mediators and moderators of functional impairment in adults with obsessive-compulsive disorder.

The current study examined correlates, moderators, and mediators of functional impairment in 98 treatment-seeking adults with obsessive-compulsive disorder (OCD). Participants completed or were administered measures assessing obsessive-compulsive symptom severity, functional impairment, resistance against symptoms, interference due to obsessive-compulsive symptoms, depressive symptoms, insight, and anxiety sensitivity. Results indicated that all factors, except insight into symptoms, were significantly correlated with functional impairment. The relationship between obsessive-compulsive symptom severity and functional impairment was not moderated by patient insight, resistance against obsessive-compulsive symptoms, or anxiety sensitivity. Mediational analyses indicated that obsessive-compulsive symptom severity mediated the relationship between anxiety sensitivity and obsessive-compulsive related impairment. Indeed, anxiety sensitivity may play an important contributory role in exacerbating impairment through increases in obsessive-compulsive symptom severity. Depressive symptoms mediated the relationship between obsessive-compulsive symptom severity and obsessive-compulsive related impairment. Implications for assessment and treatment are discussed.

Phenomenology and clinical correlates of family accommodation in pediatric anxiety disorders.

Despite evidence documenting high prevalence of family accommodation in pediatric obsessive-compulsive disorder, examination in other pediatric anxiety disorders is limited. Preliminary evidence suggests that family accommodation is common amongst children with anxiety disorders; however, the impact on clinical presentation and functional impairment has not been addressed. This study assessed the nature and clinical correlates of family accommodation in pediatric anxiety, as well as validating a mechanistic model. Participants included 112 anxious youth and their parents who were administered a diagnostic clinical interview and measure of anxiety severity, as well as questionnaires assessing internalizing and externalizing symptoms, family accommodation and functional impairment. Some form of accommodation was present in all families. Family accommodation was associated with increased anxiety severity and externalizing behaviors, having a diagnosis of separation anxiety, and increased functional impairment. Family accommodation partially mediated the relationship between anxiety severity and functional impairment, as well as externalizing behaviors and functional impairment. Family accommodation is common in pediatric anxiety disorders, and is associated with more severe clinical presentations and functional impairment. These findings highlight the importance of parental involvement in treatment and the need to specifically target accommodation practices during interventions to mitigate negative outcomes in anxious youth. Further studies utilizing longitudinal data are needed to validate mechanistic models.

The Treatment of Anxiety in Autism Spectrum Disorder (TAASD) Study: Rationale, Design and Methods

This paper describes the rationale, design, and methods of the Treatment for Anxiety in Autism Spectrum Disorders study, a three-site randomized controlled trial investigating the relative efficacy of a modular CBT protocol for anxiety in ASD (Behavioral Interventions for Anxiety in Children with Autism) versus standard CBT for pediatric anxiety (the Coping Cat program) and a treatment-as-usual control. The trial is distinct in its scope, its direct comparison of active treatments for anxiety in ASD, and its comprehensive approach to assessing anxiety difficulties in youth with ASD. The trial will evaluate the relative benefits of CBT for children with ASD and investigate potential moderators (ASD severity, anxiety presentation, comorbidity) and mediators of treatment response, essential steps for future dissemination and implementation.

A Pilot Study of Computer-Assisted Cognitive Behavioral Therapy for Childhood Anxiety in Community Mental Health Centers

Anxiety disorders among children are common, disabling, and run a chronic course without treatment. Cognitive behavioral therapy (CBT) has shown robust efficacy for childhood anxiety. However, dissemination of CBT into community mental health centers (CMHCs) is limited. Computer-assisted CBT (CCBT) programs have been developed to improve dissemination by providing a structured treatment format that allows therapists to reliably deliver evidence-based treatments with fidelity. In this pilot study involving therapists with limited CBT experience, the effectiveness, feasibility, and acceptability of a CCBT program, Camp Cope-A-Lot (Khanna & Kendall, 2008b), were examined in three CMHCs. Seventeen youth ages 7–13 years and diagnosed with a primary anxiety disorder were enrolled. Assessments were conducted by a rater not involved in treatment at baseline and posttreatment. Significant reductions in anxiety severity and impairment were demonstrated at the posttreatment assessment. High levels of family satisfaction were reported. These results provide preliminary support for the effectiveness of a computer-assisted treatment into CMHCs and warrant replication in a controlled setting.

Incidence, clinical correlates and treatment effect of rage in anxious children

Episodic rage represents an important and underappreciated clinical feature in pediatric anxiety. This study examined the incidence and clinical correlates of rage in children with anxiety disorders. Change in rage during treatment for anxiety was also examined. Participants consisted of 107 children diagnosed with an anxiety disorder and their parents. Participants completed structured clinical interviews and questionnaire measures to assess rage, anxiety, functional impairment, family accommodation and caregiver strain, as well as the quality of the childs relationship with family and peers. Rage was a common feature amongst children with anxiety disorders. Rage was associated with a more severe clinical profile, including increased anxiety severity, functional impairment, family accommodation and caregiver strain, as well as poorer relationships with parents, siblings, extended family and peers. Rage was more common in children with separation anxiety, comorbid anxiety, attention deficit/hyperactivity disorder and behavioral disorders, but not depressive symptoms. Rage predicted higher levels of functional impairment, beyond the effect of anxiety severity. Rage severity reduced over treatment in line with changes in anxiety symptoms. Findings suggest that rage is a marker of greater psychopathology in anxious youth. Standard cognitive behavioral treatment for anxiety appears to reduce rage without adjunctive treatment.

Clinical characteristics and predictors of hoarding in children with anxiety disorders

OBJECTIVE This investigation was conducted to describe the clinical of characteristics of anxious children with significant hoarding behavior and to examine the contributions of anxiety, obsessive compulsive, and inattentive and hyperactive/impulsive symptoms in the prediction of hoarding. METHOD One hundred nine children seeking treatment for an anxiety disorder and their parents completed clinician-administered and parent-report measures of emotional and behavioral symptoms, functional impairment, and hoarding symptoms. RESULTS Elevated levels of hoarding were reported for 22% of the sample. Children with elevated hoarding scored significantly higher on measures of anxiety, obsessive-compulsive, attention, social, and thought problems, rule-breaking, aggression, and overall functional impairment and had higher rates of major depressive disorder than children without hoarding. Attention problems predicted hoarding symptomology over-and-above the contributions of either anxiety or obsessive-compulsive symptoms. CONCLUSIONS Findings suggest a pattern of behavioral and emotional dysregulation for children who hoard and provide further insight into the relationships between anxiety, attention problems, and hoarding.

Frequency and Correlates of Suicidal Ideation in Pediatric Obsessive–Compulsive Disorder

This study examined the frequency and sociodemographic and clinical correlates of suicidal ideation in a sample of children and adolescents with obsessive–compulsive disorder (OCD). Fifty-four youth with OCD and their parent(s) were administered the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime, Children’s Yale-Brown Obsessive Compulsive Scale, and Children’s Depression Rating Scale-Revised. Children completed the Suicidal Ideation Questionnaire-Junior (SIQ-JR), Child Obsessive Compulsive Impact Scale-Child, and Multidimensional Anxiety Scale for Children; parents completed the Child Obsessive Compulsive Impact Scale-Parent, Swanson, Nolan, and Pelham-IV Parent Scale, and Young Mania Rating Scale-Parent Version. Seven youth endorsed clinically significant levels of suicidal ideation on the SIQ-JR. Suicidal ideation was significantly related to clinician-rated depressive symptoms, age, child-rated impairment and anxiety symptoms, and symmetry, sexuality/religiosity and miscellaneous symptom dimensions. There was no significant association between suicidal ideation and obsessive–compulsive symptom severity, comorbidity patterns, or several parent-rated indices (e.g., impairment, impulsivity). These results provide initial information regarding the frequency and correlates of suicidal ideation in treatment-seeking youth with OCD. Clinical implications are discussed, as well as directions for future research.

Process Factors Associated with Improved Outcomes in CBT for Anxious Youth: Therapeutic Content, Alliance, and Therapist Actions

Cognitive behavioral therapy (CBT) has been established as an empirically supported treatment for anxiety in youth. Recent efforts have been underway to elucidate the evidence- based process factors that are associated with successful outcomes. These factors have included both therapy content (homework; exposure tasks) and therapy process (therapeutic alliance; therapist actions). Although exposure tasks have been identified as a key component of CBT, they are not always implemented with the greatest efficacy, in session or at home. Successful implementation of exposure tasks may rely, in part, on a strong therapeutic alliance. Furthermore, therapist actions influence the alliance and client motivation and participation in homework and exposure tasks. A review of the relevant literature indicates that additional research is needed to elucidate the interaction between therapeutic process factors, such as alliance and therapist actions, and therapeutic content, including exposure tasks.

Collateral Support: Involving Parents and Schools in Treatment for Youth Anxiety

ABSTRACT Cognitive behavioral therapy (CBT) is an empirically supported and well-established treatment for youth anxiety disorders. CBT therapists often involve parents and school staff in treatment to promote the generalization of therapeutic gains across settings. To facilitate therapist communication with those who provide collateral support, we discuss both general guidelines and specific examples of how parents and teachers can best support anxious youth by acting as coping models, labeling and validating anxious feelings, rewarding brave behavior, and reducing accommodations. We provide answers to questions commonly asked by parents (e.g., “How should I respond ‘in the moment’ when my child is anxious?”) and by school personnel (e.g., “What is a useful role for a school in child treatment”). Handouts summarizing main concepts for parents and schools are provided.

Evidence-based assessment and intervention for anxiety in school psychology

Anxiety disorders are one of the most common mental health problems that children and adolescents experience worldwide, including in Australia. Anxiety is an innate reaction to a real and/or perceived threat. Although everyone experiences anxiety, youth with anxiety disorders experience excessive, pervasive and often unfounded fear or worry that can negatively impact ones’ academic, social and family life. When left untreated anxiety can lead to a number of mental health problems, as well as academic underachievement. Schools represent an ideal setting for the assessment and treatment of anxiety in youth given that youth spend the majority of their day at school and often display anxiety there. School personnel are uniquely able to identify the emergence of anxiety and can provide treatment therefore limiting common barriers of transportation and scheduling. Determination of clinical levels of anxiety is indicated by the level of interference and distress in the child’s life. Well-validated and commonly used measures to assess this include measures such as the Anxiety Disorders Interview Schedule, Multidimensional Anxiety Scale for Children, and the Spence Children’s Anxiety Scale. The most efficacious psychological treatment for youth with anxiety disorders is cognitive behavioural therapy, which teaches youth skills to reduce anxiety to manageable levels by developing more helpful thinking patterns and reducing behavioural avoidance. It is important to consider the advantages and disadvantages of identifying children at risk within the school setting, and to consider ethical and legal issues related to delivering treatment within the school setting.