Estelle Honnorat

Tick‐Borne Relapsing Fever With Cutaneous Eschar and Radiculopathy, Ethiopia

We report the first confirmed case of tick-borne borreliosis by molecular tools in a French traveler returning from Ethiopia with unusual presentation: the presence of cutaneous eschar after a hard tick-bite suggesting firstly to clinicians a diagnosis of tick-borne rickettsiosis.

Raoultella ornithinolytica: An unusual pathogen for prosthetic joint infection

We herein report the first case of a prosthetic joint infection caused by Raoultella ornithinolytica in an immunocompetent patient. The clinical outcome was favorable after a two-stage prosthetic exchange and a six-month course of antimicrobial therapy.

Osteomyelitis of sternum and rib after breast prosthesis implantation: A rare or underestimated infection?

Sternum and rib osteomyelitis complicated from breast implant infection is rare. We report a case of early sternum and rib osteomyelitis occurred during breast implant infection managed in an inter-regional referral center for bone/joint infections in the south of France.

Modern approach to infectious disease management using infrared thermal camera scanning for fever in healthcare settings.

We conducted a prospective study to assess the value of the use of infrared thermal cameras in detecting fevers in both patients and healthcare workers between May 2015 and February 2016 in a university hospital center in Southern France.

Anti-infective therapy without antimicrobials: Apparent successful treatment of multidrug resistant osteomyelitis with hyperbaric oxygen therapy

Infections due to multidrug-resistant bacteria have spread in the world and cause significant morbidity and mortality [1]. Bone and joint infection due to multidrug-resistant bacteria has become a major problem, limiting the efficacy of targeted treatment and compromising outcomes. Indeed, antimicrobial options are limited and extensive surgical procedures are required. Adjunctive hyperbaric oxygen therapy (HBO) has been reported as an effective treatment in soft tissue infection caused by anaerobic bacteria, such as gas gangrene, necrotizing fasciitis and Fournier’s gangrene. HBO has also been extensively used to improve wound healing in the treatment of diabetic foot infections and osteitis [2]. We report an apparent successful treatment of OXA-48 type carbapenemase-producing K. pneumonia osteomyelitis with HBO without any concomitant antimicrobial.

Salmonella enterica serovar Enteritidis brain abscess mimicking meningitis after surgery for glioblastoma multiforme: a case report and review of the literature

BackgroundSalmonella brain abscess associated with brain tumor is rare. Only 11 cases have been reported to date. Here we report a case of brain abscess caused by Salmonella entericaserovarEnteritidis mimicking post-surgical meningitis in a patient with glioblastoma multiforme.Case presentationA 60-year-old Algerian woman was admitted through an emergency department for a 4-day history of headache, nausea and vomiting, and behavioral disorders. Surgery for cerebral tumor excision was performed and histopathological analysis revealed glioblastoma multiforme. On the seventh day post-surgery, she presented a sudden neurological deterioration with a meningeal syndrome, confusion, and fever of 39.8°C. Her cerebrospinal fluid sample and blood cultures were positive for S. enterica Enteritidis. She was treated with ceftriaxone and ciprofloxacin. On the 17th day post-surgery, she presented a new neurological disorder and purulent discharge from the surgical wound. Brain computed tomography revealed a large cerebral abscess located at the operative site. Surgical drainage of the abscess was performed and microbial cultures of surgical deep samples were positive for the same S. enterica Enteritidis isolate. She recovered and was discharged 6 weeks after admission.ConclusionsIn this case report, a brain abscess was initially diagnosed as Salmonella post-surgical meningitis before the imaging diagnosis of the brain abscess. The diagnosis of brain abscess should be considered in all cases of non-typhoidal Salmonella meningitis after surgery for brain tumor. Surgical brain abscess drainage followed by prolonged antibiotic treatment remains a major therapeutic option.