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Circulation | 2015

Part 4: Advanced life support: 2015 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations

Mary Fran Hazinski; Jerry P. Nolan; Richard Aickin; Farhan Bhanji; John E. Billi; Clifton W. Callaway; Maaret Castrén; Allan R. de Caen; Jose Maria E. Ferrer; Judith Finn; Lana M. Gent; Russell E. Griffin; Sandra Iverson; Eddy Lang; Swee Han Lim; Ian Maconochie; William H. Montgomery; Peter Morley; Vinay Nadkarni; Robert W. Neumar; Nikolaos I. Nikolaou; Gavin D. Perkins; Jeffrey M. Perlman; Eunice M. Singletary; Jasmeet Soar; Andrew H. Travers; Michelle Welsford; Jonathan Wyllie; David Zideman

The International Liaison Committee on Resuscitation (ILCOR) Advanced Life Support (ALS) Task Force performed detailed systematic reviews based on the recommendations of the Institute of Medicine of the National Academies1 and using the methodological approach proposed by the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) Working Group.2 Questions to be addressed (using the PICO [population, intervention, comparator, outcome] format)3 were prioritized by ALS Task Force members (by voting). Prioritization criteria included awareness of significant new data and new controversies or questions about practice. Questions about topics no longer relevant to contemporary practice or where little new research has occurred were given lower priority. The ALS Task Force prioritized 42 PICO questions for review. With the assistance of information specialists, a detailed search for relevant articles was performed in each of 3 online databases (PubMed, Embase, and the Cochrane Library). By using detailed inclusion and exclusion criteria, articles were screened for further evaluation. The reviewers for each question created a reconciled risk of bias assessment for each of the included studies, using state-of-the-art tools: Cochrane for randomized controlled trials (RCTs),4 Quality Assessment of Diagnostic Accuracy Studies (QUADAS)-2 for studies of diagnostic accuracy,5 and GRADE for observational studies that inform both therapy and prognosis questions.6 GRADE evidence profile tables7 were then created to facilitate an evaluation of the evidence in support of each of the critical and important outcomes. The quality of the evidence (or confidence in the estimate of the effect) was categorized as high, moderate, low, or very low,8 based on the study methodologies and the 5 core GRADE domains of risk of bias, inconsistency, indirectness, imprecision, and other considerations (including publication bias).9 These evidence profile tables were then used to create a …


Circulation | 2015

Part 1: Executive summary: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care

Robert W. Neumar; Michael Shuster; Clifton W. Callaway; Lana M. Gent; Dianne L. Atkins; Farhan Bhanji; Steven C. Brooks; Allan R. de Caen; Michael W. Donnino; Jose Maria E. Ferrer; Monica E. Kleinman; Steven L. Kronick; Eric J. Lavonas; Mark S. Link; Mary E. Mancini; Laurie J. Morrison; Robert E. O'Connor; Ricardo A. Samson; Steven M. Schexnayder; Eunice M. Singletary; Elizabeth Sinz; Andrew H. Travers; Myra H. Wyckoff; Mary Fran Hazinski

Publication of the 2015 American Heart Association (AHA) Guidelines Update for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC) marks 49 years since the first CPR guidelines were published in 1966 by an Ad Hoc Committee on Cardiopulmonary Resuscitation established by the National Academy of Sciences of the National Research Council.1 Since that time, periodic revisions to the Guidelines have been published by the AHA in 1974,2 1980,3 1986,4 1992,5 2000,6 2005,7 2010,8 and now 2015. The 2010 AHA Guidelines for CPR and ECC provided a comprehensive review of evidence-based recommendations for resuscitation, ECC, and first aid. The 2015 AHA Guidelines Update for CPR and ECC focuses on topics with significant new science or ongoing controversy, and so serves as an update to the 2010 AHA Guidelines for CPR and ECC rather than a complete revision of the Guidelines. The purpose of this Executive Summary is to provide an overview of the new or revised recommendations contained in the 2015 Guidelines Update. This document does not contain extensive reference citations; the reader is referred to Parts 3 through 9 for more detailed review of the scientific evidence and the recommendations on which they are based. There have been several changes to the organization of the 2015 Guidelines Update compared with 2010. “Part 4: Systems of Care and Continuous Quality Improvement” is an important new Part that focuses on the integrated structures and processes that are necessary to create systems of care for both in-hospital and out-of-hospital resuscitation capable of measuring and improving quality and patient outcomes. This Part replaces the “CPR Overview” Part of the 2010 Guidelines. Another new Part of the 2015 Guidelines Update is “Part 14: Education,” which focuses on evidence-based recommendations to facilitate widespread, consistent, efficient and effective implementation …


Circulation | 2010

Part 15: First Aid 2015 American Heart Association and American Red Cross Guidelines Update for First Aid

Eunice M. Singletary; Nathan P. Charlton; Jonathan L. Epstein; Jeffrey D. Ferguson; Jan L. Jensen; Andrew I. MacPherson; Jeffrey L. Pellegrino; William “Will” R. Smith; Janel M. Swain; Luis F. Lojero-Wheatley; David Zideman

The International Liaison Committee on Resuscitation (ILCOR) First Aid Task Force was formed in 2013 to review and evaluate the scientific literature on first aid in preparation for development of international first aid guidelines, including the 2015 American Heart Association (AHA) and American Red Cross Guidelines Update for First Aid . The 14 members of the task force represent 6 of the international member organizations of ILCOR. Before 2015, evidence evaluation for first aid was conducted by the International First Aid Science Advisory Board and the National First Aid Advisory Board. Although the group responsible for evidence evaluation has changed, the goals remain the same: to reduce morbidity and mortality due to emergency events by making recommendations based on an analysis of the scientific evidence. A critical review of the scientific literature by appointed ILCOR First Aid Task Force members and evidence evaluators resulted in consensus on science statements with treatment recommendations for 22 selected questions addressing first aid interventions. These findings are presented in “Part 9: First Aid” of the 2015 ILCOR International Consensus on First Aid Science With Treatment Recommendations ,1,2 and they include a list of identified knowledge gaps that may be filled through future research. The ILCOR treatment recommendations are intended for the international first aid community, with the understanding that local, state, or provincial regulatory requirements may limit the ability to implement recommended first aid interventions. The current AHA/American Red Cross First Aid guidelines are derived from this work. New topics found in the 2015 First Aid Guidelines Update include first aid education, recognition of stroke, recognition of concussion, treatment of mild symptomatic hypoglycemia, and management of open chest wounds. Other topics have been updated based on findings from the corresponding ILCOR reviews. The roots of first aid have been recorded throughout …


Resuscitation | 2015

European Resuscitation Council Guidelines for Resuscitation 2015 Section 9. First aid

David Zideman; Emmy De Buck; Eunice M. Singletary; Pascal Cassan; Athanasios Chalkias; Thomas R. Evans; Christina M. Hafner; Anthony J. Handley; D. Meyran; Susanne Schunder-Tatzber; Philippe Vandekerckhove

Imperial College Healthcare NHS Trust, London, UK Centre for Evidence-Based Practice, Belgian Red Cross-Flanders, Mechelen, Belgium Department of Emergency Medicine, University of Virginia, Charlottesville, VA, USA Global First Aid Reference Centre, International Federation of Red Cross and Red Crescent Societies, Paris, France National and Kapodistrian University of Athens, Medical School, MSc “Cardiopulmonary Resuscitation”, Athens, Greece Hellenic Society of Cardiopulmonary Resuscitation, Athens, Greece Wellington Hospital, Wellington Place, London, UK Department of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Vienna, Austria Colchester University Hospitals NHS Foundation Trust, Colchester, UK French Red-Cross, Paris, France Austrian Red Cross, National Training Center, Vienna, Austria Belgian Red Cross-Flanders, Mechelen, Belgium Department of Public Health and Primary Care, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium Faculty of Medicine, University of Ghent, Ghent, Belgium


Annals of Emergency Medicine | 1994

Volar Dislocation of the Distal Radioulnar Joint

Eunice M. Singletary

Emergency physicians occasionally encounter dislocations of the distal radioulnar joint when these are associated with fractures of the forearm, such as the Galeazzi fracture. Isolated dislocations of the distal radioulnar joint without fracture are rare and are described in terms of the position of the ulna in relation to the radiocarpal joint. Radiographs may be difficult to interpret if a true lateral view is not obtained. This injury may be easily missed in the emergency department because of its infrequent occurrence, its relatively benign appearance, and difficulty in interpretation of radiographs.


Resuscitation | 2015

Part 9: First Aid 2015 International Consensus on First Aid Science With Treatment Recommendations

Eunice M. Singletary; David Zideman; Emmy De Buck; Wei-Tien Chang; Jan L. Jensen; Janel M. Swain; Jeff A. Woodin; Ian E. Blanchard; Rita Ann Herrington; Jeffrey L. Pellegrino; Natalie A. Hood; Luis F. Lojero-Wheatley; David Markenson; Hyuk Jun Yang; L. Kristian Arnold; Richard N Bradley; Barbara C. Caracci; Jestin N. Carlson; Pascal Cassan; Athanasios Chalkias; Nathan P. Charlton; Justin M. DeVoge; Tessa Dieltjens; Thomas R. Evans; Jeffrey D. Ferguson; Ryan C. Fringer; Christina M. Hafner; Kyee Han; Anthony J. Handley; Bryan B. Kitch

### Definition of First Aid The International Liaison Committee on Resuscitation (ILCOR) First Aid Task Force first met in June 2013. Comprising nominated members from around the globe appointed by each ILCOR member organization, the task force members first agreed to the goals of first aid and produced a definition of first aid as it might apply to the international setting. Task force members considered an agreed-upon definition essential for the subsequent development of research questions, evidence evaluation, and treatment recommendations. First aid is defined as the helping behaviors and initial care provided for an acute illness or injury. First aid can be initiated by anyone in any situation. A first aid provider is defined as someone trained in first aid who should The goals of first aid are to preserve life, alleviate suffering, prevent further illness or injury, and promote recovery. This definition of first aid addresses the need to recognize injury and illness, the requirement to develop a specific skill base, and the need for first aid providers to simultaneously provide immediate care and activate emergency medical services (EMS) or other medical care as required. First aid assessments and interventions should be medically sound and based on evidence-based medicine or, in the absence of such evidence, on expert medical consensus. The scope of first aid is not purely scientific, as both training and regulatory requirements will influence it. Because the scope of first aid varies among countries, states, and provinces, the treatment recommendations contained herein may need to be refined according to circumstances, need, and regulatory constraints. One difference between this 2015 definition and that used for the 2010 process is that the …


Circulation | 2015

Part 9: First aid

David Zideman; Eunice M. Singletary; Emmy De Buck; Wei-Tien Chang; Jan L. Jensen; Janel M. Swain; Jeff A. Woodin; Ian E. Blanchard; Rita Ann Herrington; Jeffrey L. Pellegrino; Natalie A. Hood; Luis F. Lojero-Wheatley; David Markenson; Hyuk Jun Yang; L. Kristian Arnold; Richard N Bradley; Barbara C. Caracci; Jestin N. Carlson; Pascal Cassan; Athanasios Chalkias; Nathan P. Charlton; Justin M. DeVoge; Tessa Dieltjens; Thomas R. Evans; Jeffrey D. Ferguson; Ryan C. Fringer; Christina M. Hafner; Kyee Han; Anthony J. Handley; Bryan B. Kitch

### Definition of First Aid The International Liaison Committee on Resuscitation (ILCOR) First Aid Task Force first met in June 2013. Comprising nominated members from around the globe appointed by each ILCOR member organization, the task force members first agreed to the goals of first aid and produced a definition of first aid as it might apply to the international setting. Task force members considered an agreed-upon definition essential for the subsequent development of research questions, evidence evaluation, and treatment recommendations. First aid is defined as the helping behaviors and initial care provided for an acute illness or injury. First aid can be initiated by anyone in any situation. A first aid provider is defined as someone trained in first aid who should The goals of first aid are to preserve life, alleviate suffering, prevent further illness or injury, and promote recovery. This definition of first aid addresses the need to recognize injury and illness, the requirement to develop a specific skill base, and the need for first aid providers to simultaneously provide immediate care and activate emergency medical services (EMS) or other medical care as required. First aid assessments and interventions should be medically sound and based on evidence-based medicine or, in the absence of such evidence, on expert medical consensus. The scope of first aid is not purely scientific, as both training and regulatory requirements will influence it. Because the scope of first aid varies among countries, states, and provinces, the treatment recommendations contained herein may need to be refined according to circumstances, need, and regulatory constraints. One difference between this 2015 definition and that used for the 2010 process is that the …


Annals of Emergency Medicine | 2013

Emergency Bedside Sonographic Diagnosis of Subclavian Artery Pseudoaneurysm With Brachial Plexopathy After Clavicle Fracture

Jennifer Gullo; Eunice M. Singletary; Shannon Larese

Clavicle fractures are common; however, complications are unusual. Two such complications, subclavian artery pseudoaneurysm and brachial plexopathy, are rare events that can cause significant morbidity and mortality. We report the case of a 53-year-old man who presented with shoulder swelling and right arm weakness for 1 week. Three weeks before, he had fallen and fractured his right clavicle. On presentation to our emergency department, his examination revealed a brachial plexopathy and a large supraclavicular mass. An emergency bedside triplex sonogram was performed to characterize the mass and revealed a swirling pattern within a fluid collection anterior to the subclavian artery, suggestive of a pseudoaneurysm. After computed tomography-angiography, the patient was taken to the operating room, where he underwent hematoma washout and subclavian artery stent-graft placement. This case illustrates how bedside point-of-care sonography can rapidly assist in the initial assessment of subclavian artery injury.


Resuscitation | 2017

The International Liaison Committee on Resuscitation-Review of the last 25 years and vision for the future.

Gavin D. Perkins; Robert W. Neumar; Koenraad G. Monsieurs; Swee Han Lim; Maaret Castrén; Jerry P. Nolan; Vinay Nadkarni; Bill Montgomery; Petter Steen; Richard O. Cummins; Douglas Chamberlain; Richard Aickin; Allan R. de Caen; Tzong-Luen Wang; David Stanton; Raffo Escalante; Clifton W. Callaway; Jasmeet Soar; Theresa Olasveengen; Ian Maconochie; Myra H. Wyckoff; Robert Greif; Eunice M. Singletary; Robert E. O’Connor; Taku Iwami; Laurie J. Morrison; Peter Morley; Eddy Lang; Leo Bossaert

2017 marks the 25th anniversary of the International Liaison Committee on Resuscitation (ILCOR). ILCOR was formed in 1992 to create a forum for collaboration among principal resuscitation councils worldwide. Since then, ILCOR has established and distinguished itself for its pioneering vision and leadership in resuscitation science. By systematically assessing the evidence for resuscitation standards and guidelines and by identifying national and regional differences, ILCOR reached consensus on international resuscitation guidelines in 2000, and on international science and treatment recommendations in 2005, 2010 and 2015. However, local variation and contextualization of guidelines are evident by subtle differences in regional and national resuscitation guidelines. ILCORs efforts to date have enhanced international cooperation, and progressively more transparent and systematic collection and analysis of pertinent scientific evidence. Going forward, this sets the stage for ILCOR to pursue its vision to save more lives globally through resuscitation.


Resuscitation | 2018

ILCOR Scientific Knowledge Gaps and Clinical Research Priorities for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: A Consensus Statement

Monica E. Kleinman; Gavin D. Perkins; Farhan Bhanji; John E. Billi; Janet Bray; Clifton W. Callaway; Allan R. de Caen; Judith Finn; Mary Fran Hazinski; Swee Han Lim; Ian Maconochie; Peter Morley; Vinay Nadkarni; Robert W. Neumar; Nikolaos I. Nikolaou; Jerry P. Nolan; Amelia G. Reis; Alfredo Sierra; Eunice M. Singletary; Jasmeet Soar; David Stanton; Andrew H. Travers; Michelle Welsford; David Zideman

Despite significant advances in the field of resuscitation science, important knowledge gaps persist. Current guidelines for resuscitation are based on the International Liaison Committee on Resuscitation 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations, which includes treatment recommendations supported by the available evidence. The writing group developed this consensus statement with the goal of focusing future research by addressing the knowledge gaps identified during and after the 2015 International Liaison Committee on Resuscitation evidence evaluation process. Key publications since the 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations are referenced, along with known ongoing clinical trials that are likely to affect future guidelines.

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David Zideman

Imperial College Healthcare

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Richard N Bradley

University of Texas Health Science Center at Houston

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Emmy De Buck

Katholieke Universiteit Leuven

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Anthony J. Handley

Colchester Hospital University NHS Foundation Trust

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Athanasios Chalkias

National and Kapodistrian University of Athens

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Christina M. Hafner

Medical University of Vienna

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Clifton W. Callaway

Heart of England NHS Foundation Trust

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