Eyal Peretz

Follicular B‐cell pseudolymphoma

A 60‐year‐old woman presented with a 3‐week history of a pruritic papulo‐nodular eruption on the face and trunk after a bee sting. Histological examination showed a predominantly lymphocytic infiltrate with follicular centres and tingible body macrophages. Immunohistochemically, positive staining for both kappa and lambda light chains was noted. The eruption settled with oral antihistamine and topical corticosteroid. These findings support the diagnosis of follicular B‐cell pseudolymphoma.

Vegetative pyoderma gangrenosum: an unusual presentation

A 44‐year‐old woman presented with a 6‐month history of subcutaneous nodules involving her face and shins. Her past history revealed myomatous uterus with menometrorrhagia, resulting in an iron deficiency anemia, treated by ferrum sulfate tablets. She also had diabetes mellitus type II treated by glibenclamide and metformin tablets. There was no evidence of bromide or iodide ingestion. On initial examination, several firm, tender, erythematous subcutaneous nodules, 2–4 cm in diameter, were present on the face ( Fig. 1 ) and shins ( Fig. 2 ), two with normal overlying skin. Within a few weeks, the nodule on the left shin enlarged and several superficial ulcers appeared, surrounded by purplish borders, secreting sinuses, and a vegetative exophytic surface ( Fig. 3 ). Physical examination was normal. Incisional biopsies from the ulcer margins showed pseudoepitheliomatous hyperplasia, diffuse neutrophilic infiltration with microabscess formation (Fig. .4), and the presence of a dense infiltrate composed of epithelioid cells, giant cells, and a few lymphocytes forming non‐necrotizing granulomas within the dermis and subcutaneous lobules ( Fig. 5 ). Leukocytoclastic vasculitis was also present in the lower dermis. Routine blood tests and urine analysis were normal, except for a high erythrocyte sedimentation rate (120/h) and anemia with a hemoglobin level of 10 g%. The results of the following laboratory tests were found to be within normal limits: rheumatoid factor; antinuclear antibody; C3; C4; serum immunoglobulins; serum protein electrophoresis; stool for parasites and occult blood; X‐ray of the chest, left shin, hands, and facial bones; isotopic bone scanning; abdominal ultrasonography; chest and

Solitary glomus tumour

A 42‐year‐old woman developed a purplish, tender nodule on her wrist of 6 months duration. Histological examination showed a well‐circumscribed lesion situated in the dermis and subcutis characterized by numerous, dilated thin‐walled vascular spaces surrounded by sheets of glomus cells. The histological findings are characteristic of the diagnosis of an uncommon type of glomus tumour, known as glomangioma.

Longitudinal melanonychia associated with hydroxyurea therapy in a patient with essential thrombocytosis

Occurrence of skin lesions during long‐term therapy with hydroxyurea are well described, but there have been only a few case reports of longitudinal melanonychia associated with hydroxyurea treatment. We report herein longitudinal melanonychia associated with hydroxyurea therapy in a subject with essential thrombocytosis. The prolonged time lapse (1‐year) between initiation of hydroxyurea therapy and the onset of the longitudinal melanonychia should be noted.