F. Rodriguez y Baena

Very low-dose computed tomography for planning and outcome measurement in knee replacement: THE IMPERIAL KNEE PROTOCOL

Surgeons need to be able to measure angles and distances in three dimensions in the planning and assessment of knee replacement. Computed tomography (CT) offers the accuracy needed but involves greater radiation exposure to patients than traditional long-leg standing radiographs, which give very little information outside the plane of the image. There is considerable variation in CT radiation doses between research centres, scanning protocols and individual scanners, and ethics committees are rightly demanding more consistency in this area. By refining the CT scanning protocol we have reduced the effective radiation dose received by the patient down to the equivalent of one long-leg standing radiograph. Because of this, it will be more acceptable to obtain the three-dimensional data set produced by CT scanning. Surgeons will be able to document the impact of implant position on outcome with greater precision.

A review of medical robotics for minimally invasive soft tissue surgery

Abstract This paper provides an overview of recent trends and developments in medical robotics for minimally invasive soft tissue surgery, with a view to highlight some of the issues posed and solutions proposed in the literature. The paper includes a thorough review of the literature, which focuses on soft tissue surgical robots developed and published in the last five years (between 2004 and 2008) in indexed journals and conference proceedings. Only surgical systems were considered; imaging and diagnostic devices were excluded from the review. The systems included in this paper are classified according to the following surgical specialties: neurosurgery; eye surgery and ear, nose, and throat (ENT); general, thoracic, and cardiac surgery; gastrointestinal and colorectal surgery; and urologic surgery. The systems are also cross-classified according to their engineering design and robotics technology, which is included in tabular form at the end of the paper. The review concludes with an overview of the field, along with some statistical considerations about the size, geographical spread, and impact of medical robotics for soft tissue surgery today.

Active-Constraint Robotics for Surgery

The concepts and benefits of hands-on robotic surgery and active-constraint robotics are introduced. The argument is made for systems to be cost effective and simple in order that they can be justified for a large range of surgical procedures. The case is made for robotic systems to have a clear justification, with benefits compared to those from cheaper navigation systems. The need to have robust systems, that require little surgical training and no technical presence in the operating room, is also discussed. An active constraint medical robot, the Acrobot System, is described together with its use in a prospective randomized controlled trial of unicondylar knee arthroplasty (UKA), comparing the performance of the Acrobot System with conventional surgery. Twenty-eight patients awaiting UKA were randomly allocated to have the operation performed conventionally or with the assistance of the Acrobot. The results of the trial are presented together with a discussion of the need for measures of accuracy to be introduced so that the efficacy of the robotic surgery can be immediately identified, rather than having to wait for a number of years before long-term clinical improvements can be demonstrated

Robotic control in knee joint replacement surgery.

Abstract A brief history of robotic systems in knee arthroplasty is provided. The place of autonomous robots is then discussed and compared to more recent ‘hands-on’ robotic systems that can be more cost effective. The case is made for robotic systems to have a clear justification, with improved benefits compared to those from cheaper navigation systems. A number of more recent, smaller, robot systems for knee arthroplasty are also described. A specific example is given of an active constraint medical robot, the ACROBOT system, used in a prospective randomized controlled trial of unicondylar robotic knee arthroplasty in which the robot was compared to conventional surgery. The results of the trial are presented together with a discussion of the need for measures of accuracy to be introduced so that the efficacy of the robotic surgery can be immediately identified, rather than have to wait for a number of years before long-term clinical improvements can be demonstrated.

Preoperative planning and intraoperative guidance for accurate computer-assisted minimally invasive hip resurfacing surgery

Abstract Hip resurfacing is an alternative to total hip replacement (THR) and is particularly suitable for the younger, more active patient. However, it is a more demanding procedure. This paper describes a system that enables the surgeon to plan the surgery preoperatively with optimally sized and placed components, and then transfer this plan to an intraoperative system that registers computer models to the real patient and tracks surgical tools, allowing the surgeon to ensure that the bone is resected correctly and that the components are fitted in accordance with the plan. The paper describes a series of instruments used with the system which are locked to the bone. These instruments serve the dual purpose of soft tissue retraction and bone immobilization. The system will shortly be the subject of laboratory and clinical evaluation. Registration, a cornerstone of the tracked instrument system, has been tested, and accuracy measures are provided. Experimental results for the remainder of the system will be provided after clinical trials.

Highly resolved strain imaging during needle insertion: Results with a novel biologically inspired device.

Percutaneous needle insertions are a common part of minimally invasive surgery. However, the insertion process is necessarily disruptive to the substrate. Negative side effects are migration of deep-seated targets and trauma to the surrounding material. Mitigation of these effects is highly desirable, but relies on a detailed understanding of the needle-tissue interactions, which are difficult to capture at a sufficiently high resolution. Here, an adapted Digital Image Correlation (DIC) technique is used to quantify mechanical behaviour at the sliding interface, with resolution of measurement points which is better than 0.5mm, representing a marked improvement over the state of the art. A method for converting the Eulerian description of DIC output to Lagrangian displacements and strains is presented and the method is validated during the simple insertion of a symmetrical needle into a gelatine tissue phantom. The needle is comprised of four axially interlocked quadrants, each with a bevel tip. Tests are performed where the segments are inserted into the phantom simultaneously, or in a cyclic sequence taking inspiration from the unique insertion strategy associated to the ovipositor of certain wasps. Data from around the needle-tissue interface includes local strain variations, material dragged along the needle surface and relaxation of the phantom, which show that the cyclic actuation of individual needle segments is potentially able to mitigate tissue strain and could be used to reduce target migration.

Early Developments of a Novel Smart Actuator Inspired by Nature

Current research at Imperial College focuses on the development of a novel neurosurgical probe for Minimally Invasive Surgery (MIS), which can be used to target deep lesions in the brain by exploiting the unique design of certain ovipositing wasps. While conventional neurosurgical instruments are rigid and can only be used to achieve straight-line trajectories, the biomimetic design will enable curved paths connecting any entry point to any target within the brain to be followed autonomously. This paper reports on the successful outcome of an early feasibility study, where two of the key concepts behind the novel actuator design are investigated: a biologically inspired robotic actuator was developed to demonstrate effective soft tissue traversal (i.e. motion along the surface of a soft tissue) by reciprocating custom-built anisotropic surface textures, without the need to apply an external force to push the tissue along the surface. Then, custom-designed rigid probes with bio-inspired surface topographies were fabricated and tested on cadaveric porcine brain with the aim to characterize the insertion and extraction forces due to friction and tribological interaction with biological tissue.

Insertion experiments of a biologically inspired microtextured and multi-part probe based on reciprocal motion

While there have been significant advances in minimally invasive surgical instrumentation, the majority of tools still rely on a push from the back to aid insertion into the tissue, whether the process is manual or servo assisted. In this work, a novel approach to tool insertion is proposed which is based on the concept of a multi-part probe with at least three interlocking segments. By means of a sequential insertion process, where each segment is pushed further into the tissue while stabilized by the remaining stationary parts, the multi-part probe concept is shown to successfully “insinuate itself” within a synthetic soft tissue specimen without the need for an overall forward push. The presence of an anisotropic microtextured outer probe surface is also shown to affect the overall speed of insertion and can thus be used to optimize the interaction forces at the probe-tissue interface. A measured reduction in the force transferred to the back of the specimen also suggests that this approach to tool insertion may result in reduced tissue disruption, a result which could lead to less tissue damage and a reduction in target displacement.

Minimally disruptive needle insertion: a biologically inspired solution

The mobility of soft tissue can cause inaccurate needle insertions. Particularly in steering applications that employ thin and flexible needles, large deviations can occur between pre-operative images of the patient, from which a procedure is planned, and the intra-operative scene, where a procedure is executed. Although many approaches for reducing tissue motion focus on external constraining or manipulation, little attention has been paid to the way the needle is inserted and actuated within soft tissue. Using our biologically inspired steerable needle, we present a method of reducing the disruptiveness of insertions by mimicking the burrowing mechanism of ovipositing wasps. Internal displacements and strains in three dimensions within a soft tissue phantom are measured at the needle interface, using a scanning laser-based image correlation technique. Compared to a conventional insertion method with an equally sized needle, overall displacements and strains in the needle vicinity are reduced by 30% and 41%, respectively. The results show that, for a given net speed, needle insertion can be made significantly less disruptive with respect to its surroundings by employing our biologically inspired solution. This will have significant impact on both the safety and targeting accuracy of percutaneous interventions along both straight and curved trajectories.

Development and validation of a numerical model for cross-section optimization of a multi-part probe for soft tissue intervention

The popularity of minimally invasive surgical procedures is driving the development of novel, safer and more accurate surgical tools. In this context a multi-part probe for soft tissue surgery is being developed in the Mechatronics in Medicine Laboratory at Imperial College, London. This study reports an optimization procedure using finite element methods, for the identification of an interlock geometry able to limit the separation of the segments composing the multi-part probe. An optimal geometry was obtained and the corresponding three-dimensional finite element model validated experimentally. Simulation results are shown to be consistent with the physical experiments. The outcome of this study is an important step in the provision of a novel miniature steerable probe for surgery.