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Fabian Werner

Ludwig Maximilian University of Munich

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Publication

Featured researches published by Fabian Werner.

Xenotransplantation | 2015

Pre‐clinical heterotopic intrathoracic heart xenotransplantation: a possibly useful clinical technique

Jan-Michael Abicht; Tanja Mayr; Bruno Reichart; Stefan Buchholz; Fabian Werner; I. Lutzmann; Michael Schmoeckel; Andreas Bauer; Michael Thormann; M.C. Langenmayer; Nadja Herbach; Heike Pohla; Rudolf Herzog; Christopher G.A. McGregor; David Ayares; Eckhard Wolf; Nikolai Klymiuk; Andrea Baehr; Alexander Kind; Christian Hagl; Ute Ganswindt; Claus Belka; Sonja Guethoff; P. Brenner

As a step towards clinical cardiac xenotransplantation, our experimental heterotopic intrathoracic xenotransplantation model offers a beating and ejecting donor heart while retaining the recipient′s native organ as a backup in case of graft failure. Clinically applicable immunosuppressive regimens (IS) were investigated first, then treatments known to be effective in hypersensitized patients or those with recalcitrant rejection reactions.

Symposium on Xenotransplantation, October, 23rd and 24th, 2014, Munich, Schwabing, Kardinal Wendel Haus; Transregio Collaborative Research Centre 127 of the German Research Society (DFG) and the 17th Minisymposium Xenotransplantation of the German Working Group Xenotransplantation (DAX) | 2015

Heme oxygenase 1 provid es cardioprotection after ischemia/reperfusioninjury via inhibition of postischemic inflammation

Bruno Reichart; Jan-Michael Abicht; Sonja Guethoff; Tanja Mayr; Fabian Werner; I. Lutzmann; K. Gahle; M. Waechter; J. Kindermann; Andrea Baehr; Nikolai Klymiuk; A. Wuensch; Eckhard Wolf; David Ayares; Björn Petersen; Heiner Niemann; P. Brenner

Prospects for Xenotransplantation: Identifying psychosocial and pastoral challenges Jochen Sautermeister, Richard Mathieu, Veronika Bogner Chair for Moral Theology, Catholic Theological Faculty, University Munich,

Thoracic and Cardiovascular Surgeon | 2018

Worldwide First Successful Long-term Survival after Orthotopic Cardiac Xenotransplantation of Multitransgenic Pig Hearts into Baboons Using a CD40mAb or CD40L Costimulation Blockade

P. Brenner; Bruno Reichart; Tanja Mayr; M. Längin; Sonja Guethoff; Stefan Buchholz; A. Dashkevich; S. Michel; I. Lutzmann; Fabian Werner; Andreas Bauer; Nikolai Klymiuk; Eckhard Wolf; Keith A. Reimann; W. Hermanns; D. Ayares; Christian Hagl; Stig Steen; Jan-Michael Abicht

Transplantation | 2017

40 Days Survival after Orthotopic Cardiac Xenotransplantation of Multi-Transgenic Pig Hearts in a Pig-to-Baboon Model with CD40mAb or CD40L Costimulation Blockade and Xenograft Preservation using “Steens” Cold Blood Cardioplegia Perfusion

P. Brenner; Tanja Mayr; Bruno Reichart; Sonja Guethoff; Stefan Buchholz; Alexander Dashkevich; S. Michel; I. Lutzmann; Fabian Werner; Andreas Bauer; Nikolai Klymiuk; Eckhard Wolf; Muhammad M. Mohiuddin; Keith A. Reimann; W. Hermanns; David Ayares; Christopher G.A. McGregor; Christian Hagl; Stig Steen; Jan-Michael Abicht

Xenotransplantation | 2014

Ex-vivo testing and preclinical heterotopic thoracic cardiac xenotransplantation of multi-transgenic organs

Jan-Michael Abicht; Tanja Mayr; Sonja Guethoff; Stefan Buchholz; Fabian Werner; Andrea Baehr; Nikolai Klymiuk; A. Wuensch; Eckhart Wolf; Claus Belka; David Ayares; Björn Petersen; Heiner Niemann; Anjan K. Bongoni; Robert Rieben; Christopher G.A. McGregor; Bruno Reichart; P. Brenner

Transplantation | 2018

Study for Comparison of CD40-mAb and CD40L-Ab Costimulation Blockade after Life-Supporting Orthotopic Cardiac Xenotransplantation of Multi-Transgenic Pig Hearts into Baboons with a Worldwide First Successful Long-Term Survival

P. Brenner; Bruno Reichart; Tanja Mayr; Matthias Längin; Sonja Güthoff; Stefan Buchholz; S. Michel; I. Lutzmann; Fabian Werner; Andreas Bauer; Nikolai Klymiuk; Eckhard Wolf; Keith A. Reimann; W. Hermanns; David Ayares; Christian Hagl; Stig Steen; Jan-Michael Abicht

Xenotransplantation | 2017

Orthotopic cardiac xenotransplantation of GalKO/hCD46/hTM-transgenic pig hearts into baboons (40 days survival) using a CD40mAb or CD40L-Ab costimulation blockade

P. Brenner; Tanja Mayr; Sonja Güthoff; Stefan Buchholz; Alexander Dashkevich; S. Michel; I. Lutzmann; Fabian Werner; Andreas Bauer; Nikolai Klymiuk; Eckhard Wolf; Keith A. Reimann; Muhammad M. Mohiuddin; W. Hermanns; David Ayares; Christopher G.A. McGregor; Christian Hagl; Stig Steen; Bruno Reichart; Jan-Michael Abicht

Xenotransplantation | 2017

Immunologic effects of myeloablative pre-treatment and total lymphoid irradiation in heterotopic intrathoracic pig-to-baboon cardiac xenotransplantation

Matthias Längin; Tanja Mayr; Bruno Reichart; Li Mingquian; Heike Pohla; Stefan Buchholz; Fabian Werner; Andreas Bauer; David Ayares; Eckhard Wolf; Nikolai Klymiuk; Andrea Bähr; Barbara Kessler; Alex Kind; Sonja Güthoff; P. Brenner; Jan-Michael Abicht

Thoracic and Cardiovascular Surgeon | 2017

New Standards in Orthotopic Cardiac Xenotransplantation of Multitransgenic Pig Hearts Preserved with “Steens” Cold Blood Cardioplegia Perfusion in a Pig-to-Baboon Model with CD40mAb or CD40L Costimulation Blockade

P. Brenner; Tanja Mayr; Bruno Reichart; Sonja Guethoff; Stefan Buchholz; A. Dashkevich; S. Michel; I. Lutzmann; Fabian Werner; Andreas Bauer; Nikolai Klymiuk; Eckhard Wolf; Keith A. Reimann; Muhammad M. Mohiuddin; W. Hermanns; D. Ayares; C. McGregor; Stig Steen; Jan-Michael Abicht

Thoracic and Cardiovascular Surgeon | 2016

Costimulation Blockade with CD40mAb in (Life-Supporting) Heterotopic and Orthotopic Cardiac Xenotransplantation of GalT-KO/hCD46/hTM Transgenic Pig Hearts in a Pig-to-Baboon Model

P. Brenner; Tanja Mayr; Sonja Guethoff; Stefan Buchholz; T. Pöttinger; I. Lutzmann; Fabian Werner; Andreas Bauer; Nikolai Klymiuk; Eckhard Wolf; Keith A. Reimann; Muhammad M. Mohiuddin; W. Hermanns; D. Ayares; C. McGregor; J. Lambris; Christian Hagl; Bruno Reichart; Jan-Michael Abicht

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Collaboration

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David Ayares

University of Maryland

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Keith A. Reimann

University of Massachusetts Medical School

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Christopher G.A. McGregor

Mayo Clinic

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Muhammad M. Mohiuddin

National Institutes of Health

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S. Michel

Ludwig Maximilian University of Munich

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Stig Steen

Lund University

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Sonja Güthoff

Robert Koch Institute

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Björn Petersen

Friedrich Loeffler Institute

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Heiner Niemann

Hannover Medical School

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K. Reimann

University of Massachusetts Boston

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