Fabienne Fache

Enantioselective catalytic reduction of ketones using C2-symmetric diamines as chiral ligands.

Abstract The catalytic enantioselective reduction of various prochiral ketones is reported using C 2 -symmetric diamines as ligands. Up to 99% e.e. at 100% conversion are obtained.

CHIRAL THIOUREA AS LIGAND FOR THE ASYMMETRIC REDUCTION OF PROCHIRAL KETONES

Abstract The catalytic enantioselective reduction of prochiral ketones using a chiral thiourea as ligand is reported. Several metallic precursors were tested. e.e.s up to 94% are obtained with a ruthenium complex.

Thioureas: new ligands for the metal catalyzed asymmetric reduction of carbonyl compounds

Abstract The catalytic enantioselective hydride transfer reduction of prochiral ketones using differently substituted mono and dithioureas with several catalyst precursors is reported. The best results are obtained with a ruthenium complex and a C 2 symmetric ligand.

Optically active nitrogen ligands in asymmetric catalysis. Effect of nitrogen substitution on the enantioselective hydride transfer reduction of acetophenone

Abstract Both theoretical calculations and experimental data have shown that only one diamine ligand was necessary for the Rh catalytic enantioselective hydride transfer reduction of acetophenone. A mechanism is proposed. Different aza ligands were also tested in the same reaction, using rhodium, ruthenium and iridium precursors. The structure-activity-selectivity relationship of the aza ligands is discussed.

Ureas and thioureas as Rh-ligands for the enantioselective hydride transfer reduction of acetophenone

Different chiral amines, ureas and thioureas have been synthesized and tested as ligands in the enantioselective hydride transfer reduction of acetophenone catalyzed by rhodium I. Structural effects have been noticed on both activity and selectivity.

Synthesis and electrochemical characterization of functionalized 3-substituted polypyrroles

Abstract The synthesis of two monomers, pyrrole-3-(2-methoxy-ethyl)acetate 5a and pyrrole-3-(2-(2-methoxyethoxy)ethyl)-acetate 5b , and their conditions of electropolymerization are described. These polymers exhibit good conductivity (2–5 S cm −1 ) with remarkable stability under cycling. Their electroactivity in media of various hydrophilicity is also studied.

Conductive composites based on PVDF-C2F3H and subtituted or pure poly(pyrroles)

Abstract Conducting polymer blend (alloy) films of poly(pyrrole) or derivatives with the insulating matrix PVDF-C2F3H, were synthesized (produced) by electrochemical polymerization of pyrrole or derivates on an electrode covered with the insulating film. The optimizations of the electrochemical polymerization and of the conductivities of the materials were studied. There electrical behaviors were observed at low temperature. The thermal stability of polypyrrole is improved in the high temperature region when it is incorporated in the fluorinated copolymer.