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Dive into the research topics where Fathy M. Serry is active.

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Featured researches published by Fathy M. Serry.


British Journal of Biomedical Science | 2017

Integron occurrence is linked to reduced biocide susceptibility in multidrug resistant Pseudomonas aeruginosa

Ashraf A. Kadry; Fathy M. Serry; Amira M. El-Ganiny; Ahmed M. El-Baz

Abstract Objective: Integrons are gene acquisition systems commonly found in bacterial genomes that play a major role in the dissemination of resistance to antibiotics. This work aimed to study the relationship between the presence of integrons and the reduced susceptibility of multidrug-resistant (MDR) Pseudomonas aeruginosa isolates towards different groups of biocides. Methods: The antimicrobial susceptibility patterns of 104 clinical isolates were determined against different antibiotics by the disk diffusion method. The isolates were also tested for their susceptibility to six biocides (glutaraldehyde, benzalkonium chloride, cetrimide, chlorhexidine gluconate, chlorocresol and gluconate, and phenyl mercuric nitrate) by agar dilution. The presence of integrons and resistance genes in MDR isolates were detected by polymerase chain reaction. Results: Thirty-six Pseudomonas isolates were MDR, and the majority of these isolates showed reduced susceptibility to biocides. In the MDR isolates, Class I integron was detected in 22 isolates (61.1%), while Class II and III integrons were identified in only four isolates (11.1%), In addition, aacA4 and qacE genes were detected in 22 (61.1%) and 11 (30.5%) isolates, respectively. Integron I-positive isolates showed reduced susceptibility to tested biocides. Conclusions: The current study reveals the presence of different classes of integrons, with class I being predominant. Class I integron may be responsible for generating MDR P. aeruginosa isolates with reduced susceptibility to biocides. This linkage between integrons and biocide resistance in MDR-Pseudomonas isolates is notable and could be clinically important. Strict antibiotic prescription policies and the adequate use of biocides could help in controlling this problem.


Asian Journal of Research in Pharmaceutical Science | 2012

Combating Pseudomonas aeruginosa Biofilms by Potential Biofilm Inhibitors

Hisham A. Abbas; Fathy M. Serry; Eman M. EL-Masry


Journal of Industrial Microbiology & Biotechnology | 2003

Potential biological indicators for glutaraldehyde and formaldehyde sterilization processes

Fathy M. Serry; Ashraf A. Kadry; Abdou A. Abdelrahman


Research Journal of Pharmacy and Technology | 2013

Biofilms: The Microbial Castle of Resistance

Hisham A. Abbas; Fathy M. Serry; Eman M. EL-Masry


Asian Journal of Pharmaceutical Research | 2012

Synergic interaction between antibiotics and the artificial sweeteners xylitol and sorbitol against Pseudomonas aeruginosa biofilms

Hisham A. Abbas; Fathy M. Serry; Eman M. EL-Masry


World Academy of Science, Engineering and Technology, International Journal of Pharmacological and Pharmaceutical Sciences | 2016

Activity of Commonly Used Intravenous Nutrient and Bisolvon in Neonatal Intensive Care Units against Biofilm Cells and Their Synergetic Effect with Antibiotics

Marwa Fady Abozed; Hemat K. Abd El Latif; Fathy M. Serry; Lotfi M. El Sayed


American Journal of Immunology | 2015

Factors Affecting the Response to Interferon Alpha Therapy in Egyptian HCV Patients

Naglaa Fathy Alhusseini; Fathy M. Serry; Ashraf A. Kadry; Heba Khairy


Research Journal of Pharmacy and Technology | 2013

Correlating Neonates’ Bacterial Isolates with Surrounding Environment in NICU and Detection of Biofilm Formation

Marwa Fady Abozed; Hemat K. Abd El Latif; Fathy M. Serry; Lotfi M. El Sayed


Asian Journal of Pharmacy and Technology | 2013

Activity of Commonly Used Intravenous Nutrient and Bisolvon in Neonatal Intensive Care Units against Biofilm Cells and their Synergetic Effect with Antibiotics

Marwa Fady Abozed; Hemat K. Abd El Latif; Fathy M. Serry; Lotfi M. El Sayed


Research Journal of Pharmacy and Technology | 2012

Non-steroidal anti-inflammatory drugs and sodium ascorbate potentiate the antibiotic activity against Pseudomonas aeruginosa biofilms

Hisham A. Abbas; Fathy M. Serry; Eman M. EL-Masry

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