Fathy M. Serry
Zagazig University
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Publication
Featured researches published by Fathy M. Serry.
British Journal of Biomedical Science | 2017
Ashraf A. Kadry; Fathy M. Serry; Amira M. El-Ganiny; Ahmed M. El-Baz
Abstract Objective: Integrons are gene acquisition systems commonly found in bacterial genomes that play a major role in the dissemination of resistance to antibiotics. This work aimed to study the relationship between the presence of integrons and the reduced susceptibility of multidrug-resistant (MDR) Pseudomonas aeruginosa isolates towards different groups of biocides. Methods: The antimicrobial susceptibility patterns of 104 clinical isolates were determined against different antibiotics by the disk diffusion method. The isolates were also tested for their susceptibility to six biocides (glutaraldehyde, benzalkonium chloride, cetrimide, chlorhexidine gluconate, chlorocresol and gluconate, and phenyl mercuric nitrate) by agar dilution. The presence of integrons and resistance genes in MDR isolates were detected by polymerase chain reaction. Results: Thirty-six Pseudomonas isolates were MDR, and the majority of these isolates showed reduced susceptibility to biocides. In the MDR isolates, Class I integron was detected in 22 isolates (61.1%), while Class II and III integrons were identified in only four isolates (11.1%), In addition, aacA4 and qacE genes were detected in 22 (61.1%) and 11 (30.5%) isolates, respectively. Integron I-positive isolates showed reduced susceptibility to tested biocides. Conclusions: The current study reveals the presence of different classes of integrons, with class I being predominant. Class I integron may be responsible for generating MDR P. aeruginosa isolates with reduced susceptibility to biocides. This linkage between integrons and biocide resistance in MDR-Pseudomonas isolates is notable and could be clinically important. Strict antibiotic prescription policies and the adequate use of biocides could help in controlling this problem.
Asian Journal of Research in Pharmaceutical Science | 2012
Hisham A. Abbas; Fathy M. Serry; Eman M. EL-Masry
Journal of Industrial Microbiology & Biotechnology | 2003
Fathy M. Serry; Ashraf A. Kadry; Abdou A. Abdelrahman
Research Journal of Pharmacy and Technology | 2013
Hisham A. Abbas; Fathy M. Serry; Eman M. EL-Masry
Asian Journal of Pharmaceutical Research | 2012
Hisham A. Abbas; Fathy M. Serry; Eman M. EL-Masry
World Academy of Science, Engineering and Technology, International Journal of Pharmacological and Pharmaceutical Sciences | 2016
Marwa Fady Abozed; Hemat K. Abd El Latif; Fathy M. Serry; Lotfi M. El Sayed
American Journal of Immunology | 2015
Naglaa Fathy Alhusseini; Fathy M. Serry; Ashraf A. Kadry; Heba Khairy
Research Journal of Pharmacy and Technology | 2013
Marwa Fady Abozed; Hemat K. Abd El Latif; Fathy M. Serry; Lotfi M. El Sayed
Asian Journal of Pharmacy and Technology | 2013
Marwa Fady Abozed; Hemat K. Abd El Latif; Fathy M. Serry; Lotfi M. El Sayed
Research Journal of Pharmacy and Technology | 2012
Hisham A. Abbas; Fathy M. Serry; Eman M. EL-Masry