Fatma Ezgi Can
Uludağ University
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Publication
Featured researches published by Fatma Ezgi Can.
Clinical Chemistry and Laboratory Medicine | 2017
Saim Sağ; Abdulmecit Yildiz; Aysel Aydin Kaderli; Bulent Gul; Ömer Bedir; Ercan Cegilli; Bülent Özdemir; Fatma Ezgi Can; Ali Aydinlar
Abstract Background: Contrast induced nephropathy (CIN) has been proven to be a clinical condition related to adverse cardiovascular outcomes. In recent studies, the monocyte to high density lipoprotein ratio (MHR) has been postulated as a novel parameter associated with adverse renal and cardiovascular outcomes. In this study we investigated the association of MHR with CIN in ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI). Methods: Consecutive STEMI patients treated with primary PCI were prospectively recruited. Subjects were categorized into two groups; as patients who developed CIN (CIN+) and patients who did not develop CIN (CIN–) during hospitalization. CIN was defined as either a 25% increase in serum creatinine from baseline or 44.20 µmol/L increase in absolute value, within 72 h of intravenous contrast administration. Results: A total number of 209 patients were included in the study. Thirty-two patients developed CIN (15.3%). In the CIN (+) patients, monocytes were higher [1.02 (0.83–1.39) vs. 0.69 (0.53–0.90) 109/L, p<0.01] and HDL cholesterol levels were lower [0.88 (0.78–1.01) vs. 0.98 (0.88–1.14) mmol/L, p<0.01]. In addition, MHR was significantly higher in the CIN (+) group [1.16 (0.89–2.16) vs. 0.72 (0.53–0.95) 109/mmol, p<0.01]. In multivariate logistic regression analysis, MHR, Mehran score, AGEF score and CV/eGFR were independently correlated with CIN. Conclusions: Higher MHR levels may predict CIN development after primary PCI in STEMI patients.
Acta Veterinaria-beograd | 2017
Ilker Ercan; Mehmet Onur Kaya; Ender Uzabaci; Seray Mankir; Fatma Ezgi Can; Musa Bashir Albishir
Abstract The aim of this present work was to examine statistical errors in published veterinary science articles. A total of 204 published articles (SCI or SCI-Exp) were used in this study. The articles were chosen from among those indexed in PubMed database between the years 2010 and 2014, inclusive. A total of 199 articles had at least one statistical error. The most frequently encountered statistical error among the articles published in journals indexed in SCI and in SCI-E was “errors in summarizing data”. No statistical error was found in 2.45% (n=5) of 204 (SCI: 0.98% (1/102), SCI-E: 3.92% (4/102)) articles. To reduce and prevent statistical errors in publications, the researchers must have a basic knowledge of statistics and during the study process they must consult field experts. While reviewing, the reviewers have to redirect the publications to statistical editors when needed and most importantly during the process of editing, the editors have to direct the publications to a statistics reviewer.
Journal of the Neurological Sciences | 2016
Gülfer Atasayar; Isil Ezgi Eryilmaz; Necdet Karli; Unal Egeli; Mehmet Zarifoglu; Gulsah Cecener; Ozlem Taskapilioglu; Berrin Tunca; Oznur Yildirim; Secil Ak; Gulcin Tezcan; Fatma Ezgi Can
Prophylactic therapy response varies in migraine patients. The present study investigated the relationship between the resistance to the drugs commonly used in prophylactic therapy and the possible polymorphic variants of proteins involved in the metabolism of these drugs. Migraine patients with the MDR1 3435TT genotype exhibited a better treatment response to topiramate than migraine patients with the CC and CT genotypes (p=0.020). The MDR1 C3435T polymorphism was also found to be a higher risk factor for topiramate treatment failure in a comparison of the number of days with migraine (β2=1.152, p=0.015). However, there was no significant relationship between the treatment response to topiramate and either the CYP2D6 or CYP2C19 polymorphism, and there were no significant correlations between the treatment responses to amitriptyline, propranolol, and valproic acid and the MDR1, CYP2D6 and CYP2C19 gene polymorphisms. This is the first study to investigate the effect of the polymorphic variants on prophylactic therapy response in migraine patients.
Journal of Craniofacial Surgery | 2017
Turan Ozdemir; Fatma Ezgi Can; Sefa Isiklar; Ilker Ercan; Nedim Simsek Cankur
Abstract The authors aim to determine the periorbital soft tissue anthropometric norms for Turkish young adults for right and left eyes using a noninvasive two-dimensional photogrammetric analysis. Anthropometric measurements of the periorbital soft tissue were taken from 172 female and 56 male Turkish adults aged between 18 and 24 years. The periorbital soft tissue profiles (ocular and palpebral) for males and females were digitally analyzed using linear measurements made with standardized photographic records, taken in a natural head position. Statistically significant differences were found for ocular soft tissue measurements according to gender except inner intercanthal distance (P = 0.125) and right horizontal palpebral aperture (P = 0.240). Statistically significant differences were found for palpebral soft tissue measurements according to gender except right pretarsal skin height (P = 0.112) and left pretarsal skin height (P = 0.056). Results were compared with other ethnic groups. Normal periorbital soft tissue measurements are fundamental anatomical parameters utilized in ophthalmology, optometry, ophthalmic industry, oculoplastic surgery, clinical genetics, dermatocosmetology. Further, normal anthropometric measurements generate reference data for studies in craniofacial dysmorphology, oculoplastic surgery, dermatocosmetology, and comparative physical anthropology.
Computational Statistics | 2016
Hakan Demirtas; Robab Ahmadian; Sema Atış; Fatma Ezgi Can; Ilker Ercan
Turkiye Klinikleri Tip Bilimleri Dergisi | 2018
Musa Bashir Albishir; Ilker Ercan; Ozlem Alpu; Ayşe Tanridiler; Fatma Ezgi Can
The European Research Journal | 2018
Gokhan Ocakoglu; Mehmet Onur Kaya; Fatma Ezgi Can; Sema Atış; Aslı Ceren Macunluoğlu
Nephrology Dialysis Transplantation | 2018
Abdulmecit Yildiz; Saim Sağ; Cuma Bulent Gul; Fatma Ezgi Can; Aysegul Oruc; Mehmet Fethullah Aydin; Ömer Bedir; Suat Akgur; Yavuz Ayar; Sümeyye Güllülü; Mustafa Gullulu; Alparslan Ersoy
JP Journal of Biostatistics | 2017
Ilker Ercan; Deniz Sigirli; Fatma Ezgi Can; Guven Ozkaya; Züleyha Alper
Turkiye Klinikleri Journal of Biostatistics | 2016
Fatma Ezgi Can; Sema Atiş; Gökhan Ocakoğlu; Ilker Ercan