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Dive into the research topics where Federico Canavese is active.

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Featured researches published by Federico Canavese.


Journal of Pediatric Orthopaedics B | 2006

Neurovascular complications and severe displacement in supracondylar humerus fractures in children: defensive or offensive strategy?

Djamel Louahem; Alexandre Nebunescu; Federico Canavese; Alain Dimeglio

Out of 210 children suffering from severely displaced supracondylar fractures, 76 (36%) presented with immediate neurovascular complications: 47 (22%) were neurological, 16 (8%) vascular and 13 (6%) both. Injury to two nerves simultaneously was observed in six patients. The median nerve was affected in 28 cases, the ulnar nerve in 25 and the radial nerve in 13. Posterolateral displacement was associated with 86% of damage to the median nerve and 56% of damage to the ulnar nerve. Posteromedial displacement was associated with all incidents of injury to the radial nerve with one exception. Each patient made full neurological recovery, spontaneously and following primary or secondary neurolysis performed on nerve injuries in continuity. Two situations of primary abolition of the radial pulse were encountered, one involving a pink hand in 12.5% of cases and the other involving a white hand in 1.5% of cases. There was posterolateral displacement in three out of four patients. Postoperative vascularization was revealed by immediate return of the radial pulse in 26 patients and delayed return in three others. Urgent anatomical reduction of the fracture and its early fixation are crucial. A conservative therapeutic approach is customary in the majority of neurovascular complications. Prognosis is generally excellent. Ischaemia of the limb and total ruptures of the nerve are very rare.


European Spine Journal | 2012

The growing spine: how spinal deformities influence normal spine and thoracic cage growth

Alain Dimeglio; Federico Canavese

PurposeThis article aims to provide an overview of how spinal deformities can alter normal spine and thoracic cage growth.MethodsSome of the data presented in this article are gathered from studies performed in 1980 and 1990, and their applicability to populations of different ethnicity, geography or developmental stage has not yet been elucidated. In the present article, older concepts have been integrated with newer scientific data available to give the reader the basis for a better understanding of both normal and abnormal spine and thoracic cage growth.ResultsA thorough analysis of different parameters, such as weight, standing and sitting height, body mass index, thoracic perimeter, arm span, T1–S1 spinal segment length, and respiratory function, help the surgeon to choose the best treatment modality. Respiratory problems can develop after a precocious vertebral arthrodesis or as a consequence of pre-existing severe vertebral deformities and can vary in patterns and timing, according to the existing degree of deformity. The varying extent of an experimental arthrodesis also affects differently both growth and thoracopulmonary function.ConclusionsGrowth is a succession of acceleration and deceleration phases and a perfect knowledge of normal growth parameters is mandatory to understand the pathologic modifications induced on a growing spine by an early onset spinal deformity. The challenges associated with the growing spine for the surgeon include preservation of the thoracic spine, thoracic cage, and lung growth without reducing spinal motion.


Journal of Pediatric Orthopaedics | 2011

Growth and adolescent idiopathic scoliosis: when and how much?

Alain Dimeglio; Federico Canavese; Philippe Charles

Growth in childhood and in puberty has a major influence on the evolution of spinal curvature. The yearly rate of increase in standing height and sitting height, bone age, and Tanner signs are essential parameters. Additionally, biometric measurements must be repeated every six months. Puberty is a turning point. The pubertal diagram is characterized by two phases: the first two years are a phase of acceleration, and the last three years is a phase of decelaration. Thoracic growth is the fourth dimension of the spine. Bone age is an essential parameter. Risser 0 covers two third of the pubertal growth. On the acceleration phase, olecranon evaluation is more precise than the hand. On the deceleration phase, the Risser sign must be completed by the hand maturation. A 30 degree curve at the very beginning of puberty has 100% risk of surgery. Any spinal, if progression is greater than 10 degree per year on the first two years of puberty the surgical risk is 100%.


Journal of Bone and Joint Surgery, American Volume | 2007

Skeletal age assessment from the olecranon for idiopathic scoliosis at Risser grade 0.

Yann Philippe Charles; Alain Dimeglio; Federico Canavese; Jean-Pierre Daures

BACKGROUND The main progression of idiopathic scoliosis occurs during peak height growth velocity, which is between the ages of eleven and thirteen years in girls and thirteen and fifteen years in boys and corresponds to the accelerating phase of pubertal growth. The Risser sign remains at grade 0 during this stage of growth. Triradiate cartilage closure occurs at approximately twelve years of age in girls and fourteen years in boys, which is in the middle of this phase. In addition to regular height measurements, a more detailed evaluation of skeletal maturity would be desirable prior to the identification of Risser grade 1. From the method of Sauvegrain et al., Diméglio derived a simplified method based on the radiographic appearance of the olecranon, which allows skeletal age to be assessed in six-month intervals. The purpose of this study was to determine the accuracy and the value of this simple method for the follow-up of patients with scoliosis. METHODS Five radiographic images demonstrate the typical characteristics of the olecranon during pubertal growth: two ossification nuclei, a half-moon image, a rectangular shape, the beginning of fusion, and complete fusion. This classification method was evaluated by three experienced and independent observers from lateral radiographs of the elbow in 100 boys and 100 girls with idiopathic scoliosis during the time of peak height velocity. Skeletal ages were correlated with the integral Sauvegrain method. The degree of interobserver concordance was determined, and skeletal age was compared with chronological age and the time of triradiate cartilage closure. RESULTS For the three observers, the average concordance between the Sauvegrain and olecranon methods was excellent (r = 0.977 for boys and r = 0.938 for girls). The interobserver agreement was also excellent (r = 0.987 for the olecranon method and r = 0.958 for the Sauvegrain method for boys, and r = 0.992 and r = 0.985, respectively, for girls). Skeletal and chronological age were considered to correspond to each other within a six-month range for 49% of the boys and 51% of the girls, while 25% of the boys and 26% of the girls had an advanced skeletal age and 26% of boys and 23% of girls had a delayed skeletal age. Triradiate cartilage closure occurred at the same time as the appearance of the rectangular shape of the olecranon in 65% of the boys and 61% of the girls, corresponding to skeletal ages of fourteen and twelve years, respectively. In 91% of the boys and 88% of the girls, the triradiate cartilage fused within six months before to six months after the appearance of the rectangular shape of the olecranon, which occurred between the half-moon image and the beginning of fusion of the olecranon. CONCLUSIONS The method of assessing skeletal age from the olecranon allows skeletal maturity to be evaluated in regular six-month intervals during the phase of peak height velocity. This method is simple, precise, and reliable. It complements the Risser grade-0 and the triradiate cartilage evaluation.


World journal of orthopedics | 2013

Normal and abnormal spine and thoracic cage development

Federico Canavese; Alain Dimeglio

Development of the spine and thoracic cage consists of a complex series of events involving multiple metabolic processes, genes and signaling pathways. During growth, complex phenomena occur in rapid succession. This succession of events, this establishment of elements, is programmed according to a hierarchy. These events are well synchronized to maintain harmonious limb, spine and thoracic cage relationships, as growth in the various body segments does not occur simultaneously at the same magnitude or rate. In most severe cases of untreated progressive early-onset spinal deformities, respiratory insufficiency and pulmonary and cardiac hypertension (cor pulmonale), which characterize thoracic insufficiency syndrome (TIS), can develop, sometimes leading to death. TIS is the inability of the thorax to ensure normal breathing. This clinical condition can be linked to costo-vertebral malformations (e.g., fused ribs, hemivertebrae, congenital bars), neuromuscular diseases (e.g., expiratory congenital hypotonia), Jeune or Jarcho-Levin syndromes or to 50% to 75% fusion of the thoracic spine before seven years of age. Complex spinal deformities alter normal growth plate development, and vertebral bodies become progressively distorted, perpetuating the disorder. Therefore, many scoliotic deformities can become growth plate disorders over time. This review aims to provide a comprehensive review of how spinal deformities can affect normal spine and thoracic cage growth. Previous conceptualizations are integrated with more recent scientific data to provide a better understanding of both normal and abnormal spine and thoracic cage growth.


Journal of Pediatric Orthopaedics | 2011

Unicameral bone cysts: comparison of percutaneous curettage, steroid, and autologous bone marrow injections.

Federico Canavese; James G. Wright; William G. Cole; Sevan Hopyan

Background The purpose of this study was to compare the outcome of percutaneous curettage with intralesional injection of methylprednisolone and bone marrow for unicameral bone cysts (UBCs). Methods This was a retrospective review of 46 children and adolescents with UBC treated with autologous bone marrow injection, methylprednisolone acetate injection or percutaneous curettage alone. Inclusion criteria were a radiological diagnosis of UBC and at least 24 months follow-up from the last procedure. Healing was determined using Neer/Cole 4-grades rating scale. Results The 3 treatment groups were comparable with regard to age, sex, location of the cyst, and the number of procedures undertaken. At 2 years follow-up, the proportion of patients with satisfactory healing (Neer/Cole grades I and II) was greatest among those who underwent percutaneous curettage (70%) compared with bone marrow injection (21%) and methylprednisolone acetate injection (41%) (P=0.03). We found no association between healing and age (P=0.80) nor between healing and sex (P=0.61). Conclusions These results suggest that mechanical disruption of the cyst membrane may be helpful in healing of cysts and that this technique may be preferred to simple intralesional injections. Level of Evidence Level III.


Journal of Pediatric Orthopaedics B | 2012

The French functional physical therapy method for the treatment of congenital clubfoot.

Alain Dimeglio; Federico Canavese

The French method, also called the functional physical therapy method, is a combination of physiotherapy, splinting and surgery à la carte. The French functional physical therapy method consists of daily manipulations of the newborn’s clubfoot by a specialized physical therapist, stimulation of the muscles around the foot and temporary immobilization of the foot with elastic and nonelastic adhesive taping. Physiotherapy is optimized by early triceps surae lengthening. Sequences of plaster can also be used. If conservative treatment is no longer effective, surgery should be considered. Mini-invasive surgery is a complementary procedure to nonoperative treatment (surgery ‘à la carte’). The French method reduces but does not eliminate the need for mini-invasive surgical procedures. Equinus is the most difficult deformity to treat; posterior release is sometimes necessary in a severe foot. Very severe feet (stiff–stiff; score, 16–20) are still a challenge. However, regular manipulations and splinting improve foot morphology and stiffness, and, ultimately, make surgery easier and less extensive. From the French method to the Ponseti method, the Hybrid method or the ‘the third way’, combining the advantages of both methods, is the future. The primary reason for relapses is the inability of families to maintain the correction initially achieved. The aim of this work is to provide an overview of the French functional physical therapy method and to help understand how it has evolved over time.


Spine | 2009

Intralaminar screw insertion of thoracic spine in children with severe spinal deformities: two case reports.

Stephen J. Lewis; Federico Canavese; Shayne Keetbaas

Study Design. Case report. Objective. To describe a technique of thoracic fixation in pediatric cases with anatomy not amenable to hooks and pedicle screws. Summary of Background Data. Intralaminar screws have been described in cervical and lumbar spines. There is only 1 report of the use of thoracic intralaminar screws being used for kyphotic deformity in adult patients. Methods. We performed fixation of the thoracic spine using laminar screws in 2 patients with severe spinal deformities in whom pedicle screws and hooks failed to maintain the desired correction. Clinical and radiologic features of both cases are reported. The surgical technique is described. Results. Intralaminar screws of the thoracic spine were successfully placed in 2 children with severe spinal deformities to achieve proximal fixation. Neither dorsal nor ventral cortical bone violations of the laminae were identified. In 1 case, pedicles were too small and sclerotic to accommodate pedicle screws. The second case was characterized by pedicle screw pull-out after corrective procedure, and the following revision with hooks caused fracture of the lamina. The intralaminar screws were subsequently used as proximal fixation to correct the deformity. No screw failure was encountered. Neither patient developed neurologic complications as a result of the screws. Conclusions. This procedure was used as a salvage technique in this series. However, our experience outlines the applicability of this technique at different thoracic levels and appears to be a useful tool in the armamentarium of the spinal surgeon dealing with patients with complex spinal deformities and difficult anatomy.


Spine | 2007

Dorsal arthrodesis of thoracic spine and effects on thorax growth in prepubertal New Zealand white rabbits.

Federico Canavese; Alain Dimeglio; Donatella Volpatti; Marco Stebel; Jean-Pierre Daures; Bartolomeo Canavese; Fabio Cavalli

Study Design. Dorsal arthrodesis of thoracic spine in a prepubertal New Zealand White rabbit model. Objective. Evaluating the consequences of dorsal arthrodesis on the growth of the spine, sternum, and thorax in prepubertal rabbits, through the study of CT scans. Summary of Background Data. Vertebral arthrodesis in the treatment of progressive idiopathic scoliosis in prepubertal patients is not ideal, but is still a choice in treating major deformities of the spine. Postoperative assessment of spinal deformity is essential, feasible, and recordable through CT scans. Methods. Twelve female rabbits, 9 weeks old, were subjected to surgery for dorsal arthrodesis of the upper thoracic spine. Surgery involved the implant of 2 “C”-shaped titanium bars, which were placed beside the spinous processes of the thoracic vertebrae. Three CT scans were performed, 10 (T1), 55 (T2), and 139 (T3) days after surgery. Measures were obtained by Myrian Pro software for 3 different groups: G1 with complete fusion, G2 with incomplete fusion, and G3 sham-operated. Results. The average of the dorsoventral/laterolateral thoracic diameter ratio at fused levels is lower than 1 in G1 as well as in G2; on the contrary, in G3 is higher than 1. The average growth of the sternum length between T1 and T2 and between T2 and T3 is minor in G1 than in G2 and G3. The dorsal and ventral lengths of thoracic vertebral bodies in the spinal segment D1-D6 is smaller in G1 and G2 than in G3, whereas no differences were observed between the 3 groups in the D7-D12 segment without arthrodesis. Conclusion. Dorsal arthrodesis in prepubertal rabbits changes thoracic growth patterns. In operated rabbits, the dorsoventral thoracic diameter grows more slowly than the laterolateral thoracic diameter. The sternum as well as the lengths of thoracic vertebral bodies in the spinal segment D1-D6 grow less. The crankshaft phenomenon is evident at the fused vertebral levels where there is a reduction of thoracic kyphosis.


Orthopedic Clinics of North America | 2011

Imaging in Legg-Calvé-Perthes Disease

Alain Dimeglio; Federico Canavese

Imaging in Legg-Calvé-Perthes disease should help assess the severity and the stage of the disease, detect severe forms earlier, and provide guidance to therapy. However, due to the complexity of the disease, not all examinations can be performed at the same time with the same goals. The scope of this work is to provide an overview of all imaging techniques available today, and to help understand when to use a particular examination. Advantages and limitations of plain radiographs, bone scintigraphy, magnetic resonance imaging, arthrography, computed tomography, and ultrasonography are identified.

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Alain Dimeglio

University of Montpellier

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Lorenza Marengo

Boston Children's Hospital

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André Kaelin

Boston Children's Hospital

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Bruno Pereira

Centre national de la recherche scientifique

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Matteo Paonessa

Boston Children's Hospital

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