Fernanda Maria Silveira Souto

Trombo biventricular e fibrose endomiocárdica na síndrome antifosfolípide

A SAF e uma doenca sistemica autoimune caracterizada pela deteccao plasmatica de anticorpos antifosfolipides, tais como o anticardiolipina e o anticoagulante lupico, que se manifesta clinicamente mediante: trombose arterial e/ou venosa recorrentes, trombocitopenia, abortamentos de repeticao e anemia hemolitica autoimune, alem de alteracoes cardiacas, neurologicas e cutâneas1. Constitui-se na principal causa adquirida de hipercoagulabilidade, ocorrendo em 2% da populacao geral e apresenta alta morbimortalidade2.

Dextrocardia with situs inversus associated with non-compaction cardiomyopathy

Dextrocardia is a rare condition usually diagnosed incidentally and associated with other congenital anomalies. It is characterized by the position of the heart in the right hemithorax, with its base-apex axis directed to the bottom right. Its incidence associated with situs inversus, in the general population, is 1:10.0001. Non-compaction cardiomyopathy (non-compaction CMP), in turn, has an incidence ranging from 0.014 to 1.3%2, may occur alone or associated with other congenital defects and results from failure in the process of compaction of myocardial fibers, resulting in the persistence of trabeculations and deep recesses that communicate with the ventricular cavity2. A rare association of these two diseases is described. Cases similar to the one reported have not been found3-5.

Micronutrient deficiencies in normal and overweight infants in a low socio-economic population in north-east Brazil.

Background:Micronutrient deficiencies are the most prevalent form of malnutrition worldwide. Although commonly related to underweight, micronutrient deficiencies can occur in both normal and overweight children in medium- and low-income populations undergoing nutritional transition. Objective:To describe haemoglobin and micronutrient levels in infants from a low-income area in Brazil in relation to their weight-for-length Z-score. Methods:A cross-sectional survey was undertaken of 2–11-month-old infants in Laranjeiras, a small urban community in North-east-Brazil between April 2009 and February 2010. Anthropometry and assays for haemoglobin, ferritin, plasma zinc, copper and selenium and erythrocyte zinc and copper concentrations were investigated. Results:The total number of full-term infants born in the study period was 222, of whom 153 were available for the study. Three (2%) children were wasted, 98 (66%) were of normal weight, 37 (25%) were at risk of overweight and 11 (7%) were overweight or obese. Nearly all (97%) children had at least one micronutrient deficiency, 102 (67%) had anaemia, 86 (58%) and 100 (67%) had plasma and erythrocyte zinc deficiency, respectively, and 7 (5%) and 113 (76%) had plasma and erythrocyte copper deficiency, respectively. 138 (91%) children had selenium deficiency. Except for plasma zinc, the proportion of infants with micronutrient deficiencies did not differ by weight-for-length status. Conclusions:The increased risk of overweight and micronutrient deficiencies in this population highlights the need to address the double burden of excess weight with micronutrient deficiencies in medium- and low-income settings.

Drenagem venosa pulmonar anômala em gestante identificada pela ressonância magnética cardíaca

Anomalous pulmonary venous return (APVR) is a rare cardiac anomaly defined as one or more pulmonary veins draining into a structure other than the left atrium, with venous return directly or indirectly to the right atrium. The most common form is partial APVR, in which one to three pulmonary veins drain into systemic veins or into the right atrium. We report the case of a woman diagnosed with partial APVR by magnetic resonance imaging during pregnancy.

Pulmonary Thromboembolism and Thrombus in Patent Foramen Ovale

Patent Oval Foramen (FOP) is the persistence of the opening between the atrial primum and atrial secundum in the location of the oval fossa present in about 25% of the adult population1. In generally, it is a casual finding and without hemodynamic repercussions. However, the paradoxical embolism as a cause of ischemic events due to the patency of this foramen is documented since the nineteenth century. Recent studies have shown the association between FOP and various medical conditions, some potentially serious, such as ischemic stroke (AVCi) and pulmonary embolism (TEP).