Fernando Díaz-Doutón

Curvature sensor for ocular wavefront measurement

We describe a new wavefront sensor for ocular aberration determination, based on the curvature sensing principle, which adapts the classical system used in astronomy for the living eyes measurements. The actual experimental setup is presented and designed following a process guided by computer simulations to adjust the design parameters for optimal performance. We present results for artificial and real young eyes, compared with the Hartmann-Shack estimations. Both methods show a similar performance for these cases. This system will allow for the measurement of higher order aberrations than the currently used wavefront sensors in situations in which they are supposed to be significant, such as postsurgery eyes.

Measuring the accommodative response with a double-pass system: Comparison with the Hartmann-Shack technique

The current study aims at analysing the suitability of the double-pass technique in measuring the accommodative response. A custom-built setup which allowed simultaneous double-pass and Hartmann-Shack measurements was used. Several metrics to assess the accommodative response were tested and compared. In order to validate double-pass based measurements, the accommodative response was measured in 10 young adults under monocular viewing conditions with an open field fixation test. Accommodation was stimulated with the push up method in the 0-5diopters (D) range with a 1-D step. We found no significant differences among accommodative response measurements obtained with the several metrics compared in the double-pass and the Hartmann-Shack technique. In addition, differences between the double-pass and Hartmann-Shack techniques were not statistically significant. However, we obtained slightly higher values in the measured accommodative response with the double-pass system than those usually reported by other authors. The double-pass technique takes into account all factors influencing retinal image quality. Consequently, we consider this technique as a potential powerful candidate for the analysis of accommodation.

Optics of Astigmatism and Retinal Image Quality

In the first part of this chapter, the optical condition of astigmatism is defined. The main causes and available classifications of ocular astigmatism are briefly described. The most relevant optical properties of image formation in an astigmatic eye are analysed and compared to that of an emmetropic eye and an eye with spherical ametropia. The spectacle prescription and axis notation for astigmatism are introduced, and the correction of astigmatism by means of lenses is briefly described. The formation of the retinal image for extended objects and the related blurring are also analysed, and the real limits of tolerance of uncorrected astigmatism are provided. Simulations of retinal images in astigmatic eyes, obtained by means of commercial optical design software, are also presented. Finally, the clinical assessment of retinal image quality by means of wavefront aberrometry and double-pass systems in eyes with astigmatism is presented, and current trends in research related to this topic are highlighted.

Random Changes of Accommodation Stimuli: An Automated Extension of the Flippers Accommodative Facility Test

ABSTRACT Purpose: To study the accommodative dynamics for predictable and unpredictable stimuli using manual and automated accommodative facility tests Materials and Methods: Seventeen young healthy subjects were tested monocularly in two consecutive sessions, using five different conditions. Two conditions replicated the conventional monocular accommodative facility tests for far and near distances, performed with manually held flippers. The other three conditions were automated and conducted using an electro-optical system and open-field autorefractor. Two of the three automated conditions replicated the predictable manual accommodative facility tests. The last automated condition was a hybrid approach using a novel method whereby far and near-accommodative-facility tests were randomly integrated into a single test of four unpredictable accommodative demands. Results: The within-subject standard deviations for far- and near-distance-accommodative reversals were (±1,±1) cycles per minute (cpm) for the manual flipper accommodative facility conditions and (±3, ±4) cpm for the automated conditions. The 95% limits of agreement between the manual and the automated conditions for far and near distances were poor: (−18, 12) and (−15, 3). During the hybrid unpredictable condition, the response time and accommodative response parameters were significantly (p < 0.05) larger for accommodation than disaccommodation responses for high accommodative demands only. The response times during the transitions 0.17/2.17 D and 0.50/4.50 D appeared to be indistinguishable between the hybrid unpredictable and the conventional predictable automated tests. Conclusions: The automated accommodative facility test does not agree with the manual flipper test results. Operator delays in flipping the lens may account for these differences. This novel test, using unpredictable stimuli, provides a more comprehensive examination of accommodative dynamics than conventional manual accommodative facility tests. Unexpectedly, the unpredictability of the stimulus did not to affect accommodation dynamics. Further studies are needed to evaluate the sensitivity of this novel hybrid technique on individuals with accommodative anomalies.

Technical improvements applied to a double-pass setup for performance and cost optimization

Abstract. We have studied the possibility of improving the performance, simplifying, and reducing the cost of a double-pass system by the use of alternative technologies. The system for correcting the spherical correction has been based on a focusable electro-optical lens, and a recording device based on CMOS technology and a superluminescent diode (SLED) light source have been evaluated separately. The suitability of the CMOS camera has been demonstrated, while the SLED could not break the speckle by itself. The final experimental setup, consisting of a CMOS camera and a laser diode, has been compared with a commercial double-pass system, proving its usefulness for ocular optical quality and scattering measurements.