Fernando Yañez
Pontifical Catholic University of Chile
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Publication
Featured researches published by Fernando Yañez.
Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques | 2012
Luigi Gabrielli; Andrés Enríquez; Samuel Córdova; Fernando Yañez; Iván Godoy; Ramón Corbalán
Background: Hypertrophic cardiomyopathy (HCM) is a common cause of sudden death in athletes and differentiating this condition from the nonpathological “athletes heart” remains a challenge. The development of pathological left ventricular hypertrophy (LVH) is associated with left atrial (LA) dilatation and dysfunction. LA strain and strain rate by two‐dimensional (2D) speckle tracking are novel indices of LA function and might contribute to differentiate physiological from pathological LVH among athletes with underdiagnosed HCM. Methods: We evaluated 20 patients with nonobstructive HCM, 20 highly trained athletes and 20 healthy controls matched for age, gender, and body surface area. All patients underwent a transthoracic echocardiogram with evaluation of LA strain: s‐wave (LASs); and strain rate: s‐wave (LASRs) and a‐wave (LASRa). Results: LV mass index, LA volume index, and ejection fraction were comparable between patients with HCM and athletes. Patients with HCM had a significantly lower LASs (19 + 8% vs. 43 + 8%, P < 0.01), LASRs (0.7 + 0.2 s‐1 vs. 1.6 + 0.2 s‐1, P < 0.01), and LASRa (–0.8 + 0.1 s‐1 vs. –1.4 + 0.3 s‐1, P < 0.01) compared to athletes. Among hypertrophic subjects, independent predictors of hypertrophy related to HCM were LASs and E/é ratio. Conclusions: LA myocardial deformation is significantly impaired in patients with HCM compared to athletes and healthy controls. LA strain and strain rate assessed by 2D speckle tracking should be incorporated in the evaluation of trained athletes with LVH and LA dilatation.
Revista Medica De Chile | 2013
Mónica Acevedo; Verónica Kramer; María José Bustamante; Fernando Yañez; Dominique Guidi; Ramón Corbalán; Iván Godoy; Vergara I; Jorge Jalil; Marcelo Fernández
Exercise and cardiac rehabilitation are indications with type I A evidence in most secondary cardiovascular prevention guidelines. Rehabilitation programs not only include exercise but also provide integral care and education about cardiovascular risk factors. However there is a paucity of such programs in Chile. Moreover there is a lack of awareness about the benefits of exercise and there is lack of knowledge about the details of exercise prescription in secondary prevention. Therefore, the divulgation of this knowledge is of utmost importance.
European Journal of Sport Science | 2018
Luigi Gabrielli; Marta Sitges; Mario Chiong; Jorge Jalil; María Paz Ocaranza; Silvana Llevaneras; Sebastián Herrera; Rodrigo Fernández; Rodrigo Saavedra; Fernando Yañez; Luis Vergara; Alexis Diaz; Sergio Lavandero; Pablo Castro
Abstract Moderate endurance exercise has long been considered an essential element to maintain cardiovascular health, and sedentary behaviour in the general population has been related to a significant increase in all-causes of mortality, cardiovascular disease mortality and cardiovascular disease incidence. However, a growing group of people performs an intense exercise that leads to multiple heart adaptive changes that are collectively called “athlete’s heart”. In this review, we discussed the evidence of cardiac remodelling process secondary to repetitive and strenuous exercise in some predisposed athletes that produces intense and probably deleterious changes in cardiac morphology and function with no clear clinical significance in long-term follow-up. Moreover, we also discussed the individual biological response to exercise assessed by myocardial damage, inflammation, oxidative stress, fibrosis and ventricular hypertrophy biomarkers showing different intensities with equivalent exertion.
Revista chilena de cardiología | 2012
Fernando Yañez
La actividad fisica y deporte han sido motivo de in-teres para la sociedad en general y para la medicina en particular al menos desde la antigua Grecia y en la actualidad su practica sistematica moderada es reco-mendada por diferentes organizaciones medicas, pues hay suficiente evidencia cientifica que asocia la prac-tica de actividad fisica y deporte, con la reduccion de la mortalidad general y cardiovascular, pero por otra parte, tambien es conocido que el ejercicio fisico en especial si es intenso incrementa transitoriamente el riesgo de eventos cardiovasculares y en particular la muerte subita de causa cardiaca en los portadores de estas patologias, y que aunque es muy infrecuente, es ampliamente difundida por los medios de comunica-cion produciendo inquietud en toda la comunidad, en especial cuando se trata de deportistas de alto rendi-miento, quienes -se supone- son un ejemplo de salud para toda la poblacion.Por otra parte desde del siglo XIX se plantea que tan-to que el ejercicio fisico prolongado e intenso como el entrenamiento deportivo sistematico pueden producir cambios agudos y/o adaptaciones cardiovasculares las que han sido motivo de interes para entrenadores, fi-siologos y medicos, ya sea en la busqueda de conocer su impacto en la salud como en el rendimiento de los deportistas. Asi, autores como William y Arnols en 1899 al estudiar participantes en la maraton de Bos-ton1 senalan que estos sufren signos de fatiga cardiaca como efecto de la prueba, demostrados por un incre-mento agudo del tamano cardiaco a la percusion del torax y la presencia de insuficiencia mitral a la auscul-tacion en el 84% de ellos, pero en cambio previamente Henschen en 1898, describio tambien por percusion en el torax el crecimiento del corazon en esquiadores de fondo considerandolo como un hecho fisiologico debido al entrenamiento atletico y favorable para sus resultados deportivos al compararlo con sus rendi-mientos siendo la primera descripcion en la literatura de lo que hoy con el paso del tiempo, la investigacion, el incremento del conocimiento medico y con el apo-yo de diferentes tecnicas de diagnostico llevaron a los especialistas en cardiologia y deporte a definir como “sindrome de corazon de atleta”.
Journal of the American College of Cardiology | 2012
Verónica Kramer; Fernando Yañez; Iván Godoy; Jorge Jalil; Ramón Corbalán; Carlos Navarrete; Mónica Acevedo
Methods: Prospective study in 3,217 subjects in Santiago, Chile (37% women, mean age = 53±13) without known CHD/CVD, followed in a preventive cardiology unit between 2002 and 2010. All subjects were surveyed about traditional risk factors. We measured: BMI, waist, systolic and diastolic blood pressure (BP), fasting lipids, blood sugar, and 2 non-traditional RF: aerobic capacity determined by METS (through a symptom-limited stress test) and hsCRP. FRAM was calculated for every subject. We assessed all-cause mortality in August 2011, with a median follow up of 6 ± 2 years. We constructed 4 models for mortality risk prediction: FRAM, FRAM+METS, FRAM+logCRP, FRAM+METS+logCRP. For these, ROC curves and C-index were estimated using mortality against non mortality as outcome.
Current Cardiovascular Risk Reports | 2011
Mónica Acevedo; Verónica Kramer; María José Bustamante; Fernando Yañez
European Journal of Applied Physiology | 2018
Luigi Gabrielli; Sebastián Herrera; Felipe Contreras-Briceño; Julián Vega; María Paz Ocaranza; Fernando Yañez; Rodrigo Fernández; Rodrigo Saavedra; Marta Sitges; Lorena García; Mario Chiong; Sergio Lavandero; Pablo Castro
European Heart Journal | 2018
Luigi Gabrielli; Rodrigo Saavedra; Sebastián Herrera; Julián Vega; Manuel Salinas; Rodrigo Fernández; F Contreras; Luis Vergara; Fernando Yañez; Jorge Jalil; María Paz Ocaranza; Sergio Lavandero; Mario Chiong; Pablo Castro; Marta Sitges
Revista chilena de cardiología | 2017
Claudio Chamorro; Dominique Guidi; Fernando Yañez; Gastón Chamorro
Revista chilena de cardiología | 2016
Luigi Gabrielli; Pablo Castro; Fernando Yañez