Filiz Ergin

Nature of cell kinetics in psoriatic epidermis

Background:  Psoriasis vulgaris is a common chronic inflammatory dermatosis. Disorders in keratinocyte proliferation, differentiation, inflammation and immune dysregulation are the major factors implicated in the pathogenesis of psoriasis vulgaris.

A population-based study on awareness of stroke in Turkey

Stroke is the second most common cause of mortality and a major cause of long‐term disability of adults in most countries. This study was performed to determine the level of knowledge and awareness regarding risk factors and warning signs of stroke in a selected sample. This cross‐sectional study was carried out in Aydin between November and December 2005, utilizing a study sample of 920 people registered at urban health centers. The questionnaire, prepared by the investigators, was administered by 20 trained students utilizing face‐to‐face interviews at participants’ homes. Two‐thirds of the participants knew the organ effected by stroke. The participants reported that stroke was a consequence of occlusion (28.0%) or bleeding (18.0%) in brain arteries. Paralysis/weakness of one side of the body (37.1%), speech impairment (26.8%) and numbness of one side of the body (14.2%) were reported as three major stroke warning signs. Sixty‐four percent of the participants knew at least one of these risk factors. Their primary sources of information were family and friends. Our study showed the great need for increasing awareness of risk factors and warning signs for stroke, perhaps utilizing community based education programs and the mass media.

Multiple Causes for Delay in Arrival at Hospital in Acute Stroke Patients in Aydin, Turkey

This descriptive, hospital-based study, performed in western Turkey, was designed to assess the level of pre-hospital delay and reasons for such delay in acute stroke patients, taking into consideration certain factors such as socioeconomic status, availability of transport options at onset of symptoms. Data were collected from hospital records, and a questionnaire was administered that included questions about socio-demographics, self-reported risk factors and questions related to hospital arrival. The rate of patients arriving at the hospital more than 3 hours after symptom onset was found to be 31.6% for this study. Approximately 1/3 of patients delayed going to the hospital because they were waiting for symptoms to go away while 1/3 of patients were not aware of the importance of seeking immediate medical help. There was a significant relationship between the use of ambulance transportation and length of time before arrival at the hospitals, though there was no statistically significantly relationship between the existence of stroke risk factors and hospital arrival delay. These results will likely be helpful to health care decision makers as they develop a model for stroke health care and community based training.

Domestic Violence During Pregnancy in an Eastern City of Turkey: A Field Study

Violence is an increasing and important community health problem that can be seen in any area of human life. Limited studies were found about domestic violence among pregnant women and its relation with social status of women. The aim of this study was to determine the prevalence and types of domestic violence during pregnancy, factors affecting it, women’s thoughts about violence, and relation between social status of women and domestic violence. This cross-sectional study was conducted on 253 pregnant women, using cluster and simple random sampling methods. Chi-square test and logistic regression analysis methods were used to analyze the data. Women who indicated that they have been exposed to violence at some point of their lives were 24.1% and who indicated that violence continued while they were pregnant were 11.1%. Physical violence was the most common type of violence reported (18.2%). It was found that women who had primary school or lower level of education and who made unwanted marriage suffered from more violence during pregnancy. It can be said that violence against pregnant women is still a social problem. In societies where gender roles are dominant, decision makers have to take necessary steps such as supporting education of girls to improve social status of women, increasing awareness among women in regard to personal rights and legal regulations which will contribute to the solution of the issue.

Views of Male University Students About Social Gender Roles; An Example From East of Turkey

Social gender roles refer to the roles that are traditionally associated with women and men. Social gender role includes the personal attributes and behaviors which are culturally assigned to women and men. This study was conducted to determine the views of male students at Caucasian University Health School on social gender roles at work, social life, marriage, and family life. The study was conducted on male students studying at Kars Health School, Nursing and Health Officers Department during 2007–2008 academic year. The students were given 24 statements relating to work life, social life, marriage, and family life to determine their views on social gender roles. Results indicated that 30.2% of the male students stated that women could work in a paid job, 56.9% believed in equality of women and men, 44.8% approved honor killing, 40.5% said the girls should receive education as far as they can go, 54.3% said the role of the women was to “provide moral support to their husband and children”, 37.1% stated that husbands could beat their wives under certain circumstances, 52.6% said they witnessed violence in their family at some stage of their lives, 51.7% said the women’s environment should be decided by the spouses together, 25% said the women should engage in sexual intercourse with their spouses even if they did not want to. Men who thought the role of the women was to do housework/giving birth to children/looking after the elderly members of the house, and who approved honor killing and disapproved working of their spouses, and who did not believe in equality of women and men, were found to support violence to women by men. Moreover, the students who witnessed violence at some stage of their lives supported this view as well. It was considered that the students should be educated on the definition of violence and situations involving violence, and directed to consultant services.

Tetanus seroepidemiology and factors influencing immunity status among farmers of advanced age

OBJECTIVES Tetanus, which is a vaccine preventable disease, remains a significant health concern. The mortality is especially high in elderly and farming is a significant risk factor for the disease. This study evaluates the serological immunity of tetanus and the related factors, in a farmer population. METHODS This cross-sectional study was carried out in a village located in the western part of Turkey. Volunteer farmers over the age of 50 were included in the study. The study group was determined by the systematic sampling method. IgG class tetanus antibody was measured in sera of each participant. A structured questionnaire evaluating the demographic characteristics was completed by the investigators. RESULTS A total of 293 participants (55.3% female, 44.7% male) were recruited from March 2010 to June 2010. A serum protective tetanus antitoxin level (> 0.1 IU/ml) was detected in 99 out of 293 (33.9%) of participants. According to univariate analysis; advancing age, female gender, lower education, low monthly income, presence of chronic disease, absent or incomplete vaccination history or being unvaccinated in the last ten years were risk factors for insufficient tetanus immunity. After multiple logistic regression analysis, up-to-date vaccination, gender and age were the only factors that remained independently associated with immune status (p < 0.001). CONCLUSION Farmers of advancing age are a population at risk for tetanus due to their work environment and their absent or incomplete immunization to the disease. Low rates of immunity detected highlight the importance to explore strategies in order to improve immunization status in this risky population.

Analysis of zinc and magnesium levels in pinealectomized chicks: roles on development of spinal deformity?

Melatonin is the main product of the pineal gland, and trace metals play a critical role in growth and development. The purpose of this study was to assess the serum zinc (Zn) and magnesium (Mg) levels in pinealec-tomized chicks and their possible interactions with the development of spinal deformity. Chicks were divided into two equal groups: unoperated controls (group M) and pinealectomized chicks (group N). Pinealectomies were performed at the age of 3 d. After 8 wk, serum Zn and Mg levels of 10 animals from each group were measured by spectrophotometric assay. The results of analyses were compared using the Mann-Whitney U-test. The correlation between serum Zn and Mg levels were assessed by Spearmans correlation. In this study, it was obvious that the serum Zn levels in group N were significantly lower than those in group M (2.8±0.10 vs 4.2±0.14 ppm; p<0.0005). In contrast, Mg levels in group N was high compared with the values in group M, although there was no significant difference (17.8±0.69 vs 15.7±0.85 ppm; p>0.05). In pinealectomized animals, serum Zn levels declined significantly while serum Mg levels increased, albeit insignificantly. Thus, there was a moderately positive but not statistically significant correlation between Mg and Zn levels in unoperated controls (r=0.273, p>0.05), whereas there was a negative but not statistically significant correlation between Zn and Mg levels in pinealectomized chicks (r=−0.115, p>0.05). In addition, the serum Mg to serum Zn ratio was significantly higher in group N than in the group M control (6.39±0.32 vs 3.75±0.22, respectively; p<0.001). From the results of the current study, it is clear that surgical pinealectomy in newly hatched Hybro Broiler chicks has a significant effect on serum Zn level. However, the serum Mg did not change significantly. Because serum Mg is not a good indicator of Mg status in chicks, it is speculated that other tissues, such as muscle or spine, might productively be explored as a more sensitive Mg biomarker for this model. The present study provides experimental evidence that serum trace metal levels might be affected in pinealectomized animals because of the lack of its main neurohormone melatonin.

The role of tomosynthesis in intraoperative specimen evaluation

To investigate the contribution of breast tomosynthesis to intraoperative specimen evaluation in subjects with breast cancer. Approval was obtained from the hospital ethics committee. Specimen mammography, tomosynthesis, and, if available, ultrasonography images were retrospectively assessed for 208 women who had undergone conservative surgery at our hospital between January 2013 and April 2016 after being diagnosed with breast cancer. The success of mammography, tomosynthesis, and ultrasonography in lesion detection and characterization was evaluated. Of 208 lesions, 142 (68.3%) and 198 (95.2%) were detected by mammography and tomosynthesis, respectively. All lesions were detected in 150 subjects undergoing ultrasonography (124 dense breasts, 26 fatty breasts). In 84 women who had fatty breasts, all lesions were detected both by mammography and by tomosynthesis. In 124 women with dense breasts, lesions were detected by mammography in 59 (48%) and in 114 (92%) by tomosynthesis. The success of tomosynthesis in lesion detection was found to be markedly higher than mammography (P = .00). In conclusion, tomosynthesis contributed to mammography in specimen evaluation in a total of 101 subjects. The success of tomosynthesis in lesion detection and characterization during intraoperative specimen evaluation is higher than mammography. In daily practice, ultrasonography is performed for lesions which cannot be evaluated by specimen mammography due to dense parenchymal pattern. Tomosynthesis may reduce the need for and the time and workforce allocated to specimen ultrasonography in an important group of subjects.

Awreness Research on Household Cleaning Substances-Aydın -

Objective: To determine the knowledge levels of participants at the age of above 20 about the risks of household cleaning substances and investigate of the storage conditions of them in the houses of the participants. Materials and Method: This is a cross-sectional research which involves 603 participants as head of the household from each of houses region of eight health center of Aydin, October 2007-January 2008. The questionnaire was given to the participants by a face-to-face technique. The storage conditions of household cleaning substances were also investigated and filled a control list for each houses. Results: There were at least one household cleaning substance of 97.7% of the houses. The most of them were storaged in the bathroom (88.6%). In the houses, cleaners were founded attainable level for the childrens at the age of under the six as at the varying percents between 86-100 % according to storage part of the houses. Conclusion: Child-specific health and environment control/investigation lists for practical using during periodical visiting of the health staffs should be developed. Specific training programs can be prepared and performed to increase knowledge and awareness level of the community.